Abstract:
:Acne vulgaris, a multifactorial condition often conferring significant psychosocial morbidity, affects an estimated 40 million people in the United States. The majority of these individuals are adolescents and young adults. The pathophysiology of the condition is still not fully known, but it is believed to be related in part to excess sebum production, follicular hyperkeratinization, microbial colonization by P acnes, and inflammation. Prior to initiating treatment in a female patient, a hyperandrogenic state must be considered and ruled out through history, physical exam, and laboratory evaluation if necessary. Treatment options are vast and include hormonal therapy among others. Hormonal therapies have long been noted to reduce acne lesions and offer a valuable adjuvant to standard therapy. Hormonal agents are thought to improve acne by blocking the androgen receptor and/or decreasing circulating androgens which leads to decreased sebum production. Hormonal treatment options include spironolactone, other antiandrogens, and oral contraceptives. The use of these agents to effectively treat acne has been demonstrated in several randomized, placebo-controlled clinical trials. Optimal results are often achieved with combination therapy with the goal of targeting multiple pathogenic pathways in acne development.
journal_name
J Pediatr Adolesc Gynecoljournal_title
Journal of pediatric and adolescent gynecologyauthors
Olutunmbi Y,Paley K,English JC 3rddoi
10.1016/j.jpag.2007.07.004subject
Has Abstractpub_date
2008-08-01 00:00:00pages
171-6issue
4eissn
1083-3188issn
1873-4332pii
S1083-3188(07)00248-3journal_volume
21pub_type
杂志文章,评审abstract::Receiving the diagnosis of Primary Ovarian Insufficiency (POI) can be emotionally difficult and confusing for young girls and their families. Parents need assistance in knowing how to help their daughters understand and live with the diagnosis in a way that allows for healthy growth and development. This paper provide...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,病人教育讲义
doi:10.1016/j.jpag.2010.12.004
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Skene's glands are believed to be homologues of the prostate gland derived from the urogenital sinus.(1) Complications of Skene's glands occur most often in the third and fourth decades and are rarely seen in premenarchal females. CASE:A 3-year-old presented to her pediatrician with a 9-day complaint of vul...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2007.11.004
更新日期:2009-02-01 00:00:00
abstract:STUDY OBJECTIVE:To describe the prevalence and correlates of vaginal douching among urban African American adolescents and to examine the association between douching and sexually transmitted infection (STI) status. DESIGN:Demographic, psychosocial, and behavioral data were collected through cross-sectional, self-admi...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2011.07.017
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Juvenile granulosa cell tumors (JGCT) are rare ovarian tumors that frequently present with precocious puberty. Presentation in infants less than a year of age is also rare. CASE:We describe a 10-month-old infant who presented with both premature thelarche and adrenarche due to JGCT. Laboratory evaluation re...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2008.08.001
更新日期:2009-10-01 00:00:00
abstract:STUDY OBJECTIVE:To determine if pregnant adolescents interested in group-based prenatal care have different demographic and psychosocial characteristics than those interested in individual prenatal care. Factors that influence the preferred model of prenatal care patients were assessed. DESIGN, SETTING, AND PARTICIPAN...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2015.03.006
更新日期:2015-12-01 00:00:00
abstract:PURPOSE OF REVIEW:We adopted a life-cycle approach to further our understanding of the natural history of the cystic forms of uterine adenomyosis first described by Cullen in 1908. SEARCH STRATEGY:Scopus and PubMed were searched for all terms referring to cystic variant of adenomyosis or adenomyoma. References found i...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2014.05.008
更新日期:2015-12-01 00:00:00
abstract:STUDY OBJECTIVE:Congenital uterine anomalies are common, although the majority are asymptomatic. When an obstructed system exists, women may present with abdominal pain, or dysmenorrhea. Removal of the obstructed horn may be required in the symptomatic patient. In the past, surgical treatment necessitated a laparotomy....
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2006.08.003
更新日期:2007-06-01 00:00:00
abstract:STUDY OBJECTIVE:To document physical and symptomatic changes in adolescent females using depot medroxyprogesterone acetate (DMPA) for contraception. DESIGN:A 30-month prospective experimental study using a convenience sample of subjects. SETTING:A pediatric primary care clinic in Milwaukee, Wisconsin that serves an u...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/s1083-3188(97)70039-1
更新日期:1997-02-01 00:00:00
abstract:STUDY OBJECTIVE:Survival into adulthood is now a reality for many adolescents facing cancer. Fertility preservation (FP) is rapidly advancing, but oncology providers and health systems struggle to incorporate the newest FP technologies into the clinical care of adolescents. Our objective was to systematically review an...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2016.04.005
更新日期:2016-12-01 00:00:00
abstract:STUDY OBJECTIVE:On the basis of longitudinal data collected over 6 years, the changes in delinquent behavior and the related sociodemographic, personal, and family determinants were examined in this study. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: A 6-year longitudinal research design was...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2015.10.009
更新日期:2016-02-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate the attitudes and practices of cystic fibrosis (CF) providers toward sexual and reproductive health (SRH) care in young women with CF. DESIGN, SETTING, PARTICIPANTS, AND INTERVENTIONS:Adult and pediatric US CF providers were sent an online survey exploring their attitudes toward SRH impo...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2017.01.009
更新日期:2017-10-01 00:00:00
abstract:STUDY OBJECTIVE:To learn the relationship between X;autosome chromosome translocation and hypoplastic external genitalia. BACKGROUND:An X;autosome translocation usually presents with phenotypic features similar to Turner syndrome. PARTICIPANTS:We present three female siblings and their mother with X;autosome transloc...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/s1038-3188(99)00011-x
更新日期:1999-08-01 00:00:00
abstract:STUDY OBJECTIVES:To determine the impact of antiandrogen treatment on bone density and geometry. DESIGN:Prospective cohort investigation. SETTING:Academic research institute. PARTICIPANTS:38 (age 14.96 ± 1.42 yr) subjects with PCOS. INTERVENTIONS:Treated with metformin (n = 17) or metformin and antiandrogen (n = 21...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2011.11.010
更新日期:2012-06-01 00:00:00
abstract:OBJECTIVE:To estimates rates and correlates of disclosure of date/acquaintance rape or attempted rape and verbally coercive sex among a diverse sample of adolescent and young adult females. DESIGN:Secondary data analysis of cross sectional data. SETTING:Urban adolescent healthcare facility. PARTICIPANTS:Adolescents ...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2004.11.006
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Giant paratubal cysts are rare lesions that can present management challenges due to their enormous size. We present a modified minimally invasive approach for effective surgical management of giant paratubal cysts. CASE:A 19-year-old adolescent with worsening abdominal distention and metrorrhagia was diagn...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2014.11.002
更新日期:2015-10-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the incidence of hemostatic disorders in a population of adolescents with various patterns of abnormal uterine bleeding (AUB). DESIGN:Retrospective observational study. SETTING:University hospital. PARTICIPANTS:One hundred thirteen adolescents with AUB; mean age at menarche and mean age a...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2013.06.003
更新日期:2013-10-01 00:00:00
abstract:STUDY OBJECTIVE:To assess the effect of providing standardized counseling to improve the rates of contraception initiation and utilization among detained young women. This was a quality improvement (QI) project conducted at a large urban juvenile short-term detention center. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2018.01.002
更新日期:2018-08-01 00:00:00
abstract:STUDY OBJECTIVE:Polycystic ovarian syndrome (PCOS) is a major endocrine disorder afflicting women of reproductive age group. Women with PCOS suffer from depressive and anxiety disorders and they are more likely to be depressed compared to healthy women. However, no studies have assayed the perception of the clinical ma...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2013.04.005
更新日期:2013-10-01 00:00:00
abstract:STUDY OBJECTIVE:To describe contraceptive use among female adolescents initiating outpatient treatment for opioid use disorder. DESIGN:Retrospective chart review. SETTING:Outpatient clinic providing medication-assisted treatment for substance use disorders to adolescents and young adults. PARTICIPANTS:Nonpregnant fe...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2017.11.002
更新日期:2018-04-01 00:00:00
abstract:STUDY OBJECTIVE:To explore the potential occurrence of long-term side effects and tolerability of gonadotropin-releasing hormone agonist (GnRHa) plus 2 different add-back regimens in adolescent patients with endometriosis. DESIGN:Follow-up questionnaire sent in 2016 to patients who participated in a drug trial between...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jpag.2018.03.004
更新日期:2018-08-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to further evaluate the pathologic features of epithelial ovarian neoplasms and their relative frequency among all ovarian tumors in the adolescent population. DESIGN:We conducted a retrospective pathologic study of all cases of epithelial ovarian neoplasms in adolescents (aged 11-...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2011.07.011
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:To describe attitudes and perceptions toward acceptability of human papilloma virus (HPV) vaccination among inner city Caribbean (CA) and African American (AA) adolescents and their parents, and discuss correlates that may be associated with these factors. DESIGN:Questionnaire survey. SETTING:An adolescent ...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2010.02.002
更新日期:2010-08-01 00:00:00
abstract::Today's generation of adolescents and young adults have been labeled "digital natives" given that they have had access to digital technology since birth. In this review, we address 2 critical areas affecting adolescents' reproductive health and social media. First, we address the current state of the science across se...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2020.06.016
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To examine menstrual patterns and effects of menstrual disorders on social and academic lives of undergraduate students in Kano, Nigeria. PARTICIPANTS:Students attending Bayero University Kano, Nigeria (n = 383). INTERVENTION:Self-administered questionnaires. MAIN OUTCOME MEASURES:Sociodemographic characte...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2012.08.006
更新日期:2012-12-01 00:00:00
abstract:STUDY OBJECTIVE:The purpose of this study was to: 1) describe parental sources of information about human papillomavirus (HPV) vaccination for adolescents, 2) understand how parental sources of information about HPV vaccine are associated with adolescent HPV vaccine uptake, and 3) understand if the relationship between...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jpag.2016.05.003
更新日期:2016-12-01 00:00:00
abstract::The low rates of actual contraceptive failure and high rates of contraceptive use among young women highlights that choice of contraceptive method and patterns of contraceptive use greatly influence unintended pregnancy risk. Promoting contraceptive use among adolescent and young adult women requires supportive health...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jpag.2020.12.008
更新日期:2020-12-14 00:00:00
abstract:STUDY OBJECTIVE:The aim of our study was to determine the etiologic distribution of 46,XX disorder of sexual development (DSD) according to the new DSD classification system and to evaluate the clinical features of this DSD subgroup in our patient cohort. PARTICIPANTS:The evaluation criteria and clinical findings of 9...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2014.01.106
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Prenatal ovarian torsion is a rare but significant gynecologic abnormality. Current literature has yet to establish standard management in the case of auto-amputated adnexa secondary to ovarian torsion in the neonate. CASES:We report 2 cases of abdominal masses that were diagnosed in the antenatal period an...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章
doi:10.1016/j.jpag.2013.06.019
更新日期:2014-04-01 00:00:00
abstract::This review examines the prevalence, associated morbidity, and treatment of primary dysmenorrhea in adolescent girls. Relevant literature was examined by systematic, evidence-based review using MEDLINE and Cochrane Collaboration databases. Dysmenorrhea is highly prevalent during adolescence. Despite differences in mea...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/s1083-3188(00)00076-0
更新日期:2001-02-01 00:00:00
abstract:OBJECTIVES:To review the etiologies, diagnosis, and treatment options of adolescent endometriosis. METHODS:Review of publications relating to adolescent endometriosis. RESULTS:Endometriosis occurs in adolescents as young as 8 years of age; furthermore, there have been documented cases of endometriosis occurring prior...
journal_title:Journal of pediatric and adolescent gynecology
pub_type: 杂志文章,评审
doi:10.1016/s1083-3188(03)00066-4
更新日期:2003-06-01 00:00:00