Abstract:
:Serum concentrations of C-reactive protein (CRP), interleukin-6 (Il-6) and tumor necrosis factor-alpha (TNF-alpha), as well as body mass index (BMI) were measured in a series of 36 elderly subjects (18 males, 18 females) of mean age 76.8+/-4.5 years, in order to assess whether these parameters are involved in senile osteoporosis (SOP). Bone mineral density was determined, by a dual-emission X-ray absorbimetry (dexa) method on the nondominant radius, as a measure of SOP. These studies revealed the following main results: (i) the female/male ratio of SOP at this age is 4:1; (ii) overweight has a sort of protection against SOP in females; (iii) increased Il-6 and TNF-alpha serum levels when observed in either of the sexes were accompanied by SOP, indicating that these parameters may be involved in provoking and maintaining SOP; (iv) elevated serum CRP levels indicate, in most elderly subjects, the presence of inflammation in SOP which has been considered previously as a merely 'wear and tear'-induced disease.
journal_name
Arch Gerontol Geriatrjournal_title
Archives of gerontology and geriatricsauthors
Maugeri D,Russo MS,Franzé C,Motta V,Motta M,Destro G,Speciale S,Santangelo A,Panebianco P,Malaguarnera Mdoi
10.1016/s0167-4943(98)00110-1subject
Has Abstractpub_date
1998-09-01 00:00:00pages
159-63issue
2eissn
0167-4943issn
1872-6976pii
S0167-4943(98)00110-1journal_volume
27pub_type
杂志文章abstract::The world's population is aging and there is need for more geriatricians. Current training programs, however, are not producing a sufficient number of geriatricians to meet that need, largely because students and residents lack interest in a career in geriatrics. A variety of reasons have been suggested to explain tha...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/S0167-4943(09)70007-X
更新日期:2009-12-01 00:00:00
abstract::This study was to examine an effect of such an exercise program on preventing conditions requiring long-term care in the Japanese frail elderly who participated in a Tai Chi Yuttari-exercise program. The first-intervention group underwent an intervention program by participating in a Tai Chi Yuttari-exercise session o...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2010.11.010
更新日期:2011-05-01 00:00:00
abstract::The study was to compare the ability of BMI, MAC and CC in predicting nutritional status, functional ability and follow-up mortality risk of older adults. The study purposively recruited 160 of 320 residents of a nursing home in Central Taiwan to serve as subjects. Residents who were ≥65 years old, cognitively normal,...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.05.015
更新日期:2012-05-01 00:00:00
abstract:AIMS:Type 2 Diabetes Mellitus(DM) is a well-known risk factor for cognitive impairment. Recent evidences suggest that Dipeptidyl peptidase-4(DPP-4) inhibitors might have neuroprotective effects. Therefore, this study aimed to investigate vildagliptin, a DPP-4 inhibitor, effects on cognitive function in older patients w...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2020.104013
更新日期:2020-01-01 00:00:00
abstract::Casual blood pressure (BP) measurements may sometimes indicate the presence of cardiovascular morbidity and mortality, but the correlations between BP values and the subsequent occurrence of such complications are low. This may depend on the known inability of casual BP measurements to reflect accurately the 24-hour m...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/0167-4943(96)86925-1
更新日期:1996-01-01 00:00:00
abstract::Self-rated health is a strong predictor of mortality, morbidity, future functional capacity and the quality of life. Measures of self-rated health have been collected fairly regularly since the 1980s, but few of them focus on self-rated health among the elderly war veterans. The aim of this study was to examine change...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.09.011
更新日期:2012-09-01 00:00:00
abstract::This study aims to examine differences in cognitive impairment and mobility disability between older men and women in Ouagadougou, Burkina Faso, and to assess the extent to which these differences could be attributable to gender inequalities in life course social and health conditions. Data were collected on 981 men a...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2013.06.007
更新日期:2013-11-01 00:00:00
abstract::We sought to determine if low ANSS, usually associated with high pressure ulcer risk, are also associated with post-operative complications following spine fracture surgery in the elderly. This was a retrospective cross-sectional study conducted at the division of orthopedic surgery in a tertiary medical center betwee...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.08.007
更新日期:2012-07-01 00:00:00
abstract::The management of advanced cancer in the older person is variable. In some patients with common malignancies chemotherapy may palliate symptoms and prolong survival, while in other patients chemotherapy is a cause of overwhelming toxicity and supportive care is the preferred form of treatment. We explored the principl...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/0167-4943(90)90015-x
更新日期:1990-03-01 00:00:00
abstract::Age-related changes of the hippocampal mossy fibre system were studied in rats of different ages (4, 12, and 24 months) using the Timm's histochemical technique for the detection of tissue stores of zinc and heavy transitional metals. Quantitative image analysis and microdensitometry techniques were applied for the ev...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/0167-4943(89)90071-x
更新日期:1989-01-01 00:00:00
abstract::Chronic musculoskeletal pain is a common, disabling condition that affects at least one in four elderly people. Figures are much higher in nursing homes, in which as many as 45-80% of residents has pain that contributes to functional impairment and decreased quality of life. Multiple comorbidity, under-reporting of sy...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2007.01.024
更新日期:2007-01-01 00:00:00
abstract::Obesity has gained a great importance during the last decades, and this fact stimulated numerous studies regarding the genetic causes of this disease. A recently discovered new molecule, called leptin, raised a wide interest. It is a product of the adipocytes, it exerts inhibitory effects on the center of appetite and...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/s0167-4943(01)00195-9
更新日期:2002-02-01 00:00:00
abstract::Although otherwise extensively researched, one aspect of social functioning in older people that has received less attention is its association with staying at home for as long as possible. This 10-year follow-up examines factors of social functioning that support older people's independent living in their own homes a...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2007.12.001
更新日期:2009-03-01 00:00:00
abstract::Aging and malnutrition are connected by social and pathological factors; many studies show that 60-80% of hospitalized elderly patients are malnourished. The aim of this study was to establish a correlation between age and nutritional parameters in malnourished, hospitalized, elderly patients before and after restitut...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/0167-4943(96)87005-1
更新日期:1996-01-01 00:00:00
abstract::Though frailty status has recently been linked to poorer quality of life, the impact of income on this relationship has not previously been investigated. Data from a population-based panel study, the English Longitudinal Study of Aging, on 3225 participants aged 65-79 years were analyzed cross-sectionally. A Frailty I...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2013.12.008
更新日期:2014-05-01 00:00:00
abstract::We studied whether increased blood homocysteine is a predictor for incident depression in a population-based cohort aged >or=65. A total of 240 men and 217 women were identified at baseline and were assessed 4 years later for depression (Geriatric Depression Scale, GDS >or=10 or use of antidepressants). Risk of incide...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2009.06.009
更新日期:2010-07-01 00:00:00
abstract::The aim of the study was to evaluate the subjective functional outcome of total hip arthroplasty (THA) in patients who underwent hydrotherapy (HT) 6 months after discharge. A prospective randomized study was performed on 70 elderly inpatients with recent THA, who completed a rehabilitation program. After randomization...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.archger.2009.02.005
更新日期:2010-01-01 00:00:00
abstract::In this work, it was examined the possibility of lipopolysaccharide (LPS) causing cellular senescence in lung alveolar epithelial cells. Then, it was clarified how this cellular senescence phenomenon is associated with oxidative stress effect induced by LPS and whether antioxidants could inhibit reduced cellular viabi...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.07.016
更新日期:2012-03-01 00:00:00
abstract::Increasing evidence indicates that inflammation has a substantial role in the pathogenesis and progression of AD. RDW, a measure of heterogeneity in the size of circulating erythrocytes, is associated with inflammatory markers in many numerous diseases. Present study was undertaken to assess the interrelationships bet...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2012.10.002
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Elderly in Egypt is approximately 7.2% of the population. The main physical health problems affecting old age is Non-communicable diseases (NCDs). Depression is the commonest geriatric psychiatric disorder related to various life events. Malnutrition is associated with poor health, and cognitive impairment. ...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2016.06.001
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To investigate the sex-difference in relation to the association between moderate-vigorous physical activity (MVPA) and sedentary time (ST) patterns with frailty. METHOD:Accelerometry from ≥50 year olds from the National Health and Nutrition Examination Survey (2003-04/2005-06 cycles) were included. Bouted a...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2019.103972
更新日期:2020-01-01 00:00:00
abstract::In this study, we aimed to determine the factors associated with recurrent falls in aged-care inpatients at a tertiary hospital, with a focus on the cognitive domains of recurrent fallers. We retrospectively examined the characteristics of 70 aged-care inpatients who sustained ≥ 2 falls; 269 patients who sustained 1 f...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2010.08.012
更新日期:2011-09-01 00:00:00
abstract::The purpose of the study was to examine dyadic factors of home modification in frail older adults and their informal caregivers for improving health care at home in the United States. A secondary data analysis used the National Alliance for Caregiving and the American Association of Retired Persons caregiver survey da...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2014.07.012
更新日期:2014-11-01 00:00:00
abstract::Aging is a well-known risk factor associated with oral diseases. The aim of this cross-sectional study was to compare tooth loss and periodontal health between the relatively young elderly (65-74 years) and the old elderly (≥ 75 years) and to investigate the strength of the age effect on oral health status in the Kore...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.04.021
更新日期:2011-09-01 00:00:00
abstract::The objective of this study was to evaluate the effects of growth and aging on the antioxidant capacities of rat serum and brain, by using two different reactive oxygen species (ROS) generators and two different methods of expressing the results. The antioxidant capacity was determined by using the oxygen radical abso...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/0167-4943(95)00674-5
更新日期:1996-01-01 00:00:00
abstract::Falls among the elderly is a major public health concern. There has been recent extensive research on the effects of Tai Chi in fall prevention among the elderly. As such, we undertook a systematic review to look for evidence on the effect of this intervention. There were seven randomized controlled trials, which met ...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,评审
doi:10.1016/j.archger.2008.02.018
更新日期:2009-05-01 00:00:00
abstract::The purpose of this study was to evaluate the effect of structured group reminiscence therapy on behavior competence and physical functioning and to compare effectiveness of the intervention by stage of dementia in Taiwanese elders residing in institutional settings. A longitudinal experimental design was used. Sevent...
journal_title:Archives of gerontology and geriatrics
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.archger.2008.08.007
更新日期:2009-09-01 00:00:00
abstract::We aimed at investigating the relationship between socioeconomic (SES) and health status in the context of an observational multicenter study of elderly hospitalized patients. Our series consisted of 473 patients aged 70 years or more. K-means cluster analysis was used to generate 3 clusters on the basis of age, gende...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章,多中心研究
doi:10.1016/j.archger.2009.09.026
更新日期:2009-01-01 00:00:00
abstract::We have described twelve dementia patients with noise making. We categorized noise making into (i) persistent screaming, (ii) perseverative vocalization, (iii) continuous chattering, muttering, singing or humming, and (iv) swearing, grunting and bizarre noise-making. The patients' ages ranged from 70 to 92 years with ...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/s0167-4943(02)00169-3
更新日期:2003-05-01 00:00:00
abstract::We previously reported the regional differences in the IELs present in the proximal (P), middle (M), and distal (D) parts of the small intestine, cecum (Ce), and colon (Co) of mice. In this study, we investigated the age-dependent changes in the regional differences of IELs from young adult to aged mice. In this exper...
journal_title:Archives of gerontology and geriatrics
pub_type: 杂志文章
doi:10.1016/j.archger.2011.07.009
更新日期:2012-09-01 00:00:00