当前位置： SCI文献检索 > ARCHIVES OF GERONTOLOGY AND GERIATRICS期刊下所有文献 > The leptin, a new hormone of adipose tissue: clinical findings and perspectives in geriatrics.

The leptin, a new hormone of adipose tissue: clinical findings and perspectives in geriatrics.

Abstract：

:Obesity has gained a great importance during the last decades, and this fact stimulated numerous studies regarding the genetic causes of this disease. A recently discovered new molecule, called leptin, raised a wide interest. It is a product of the adipocytes, it exerts inhibitory effects on the center of appetite and increases the energy expenditure of the organism. The present study evaluated blood leptin levels in 57 elderly subjects and searched for eventual correlations between this parameter and the age, the body mass index (BMI), the fat body mass (fat%), the waist (W) and hip (H) circumference, as well as the ratio (R) of these latter two values (WHR). Blood leptin levels do not correlate with age, body height and the WHR, but display significant positive correlations with the body weight, the BMI, the fat%, the W, H and WHR. A deeper knowledge on leptin and the correlations of this hormone with other body parameters might be helpful in a better understanding of several pathogenetic mechanisms related to aging and involved in a deterioration of the quality of life in elderly, like multiple atherosclerotic and metabolic diseases (diabetes, dyslipidemias).

journal_name

Arch Gerontol Geriatr

journal_title

Archives of gerontology and geriatrics

authors

Maugeri D,Bonanno MR,Speciale S,Santangelo A,Lentini A,Russo MS,Calanna A,Malaguarnera M,Motta M,Testai' M,Panebianco P

doi

10.1016/s0167-4943(01)00195-9

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

47-54

issue

1

eissn

0167-4943

issn

1872-6976

pii

S0167494301001959

journal_volume

34

pub_type

杂志文章

相关文献

ARCHIVES OF GERONTOLOGY AND GERIATRICS文献大全
  • Oxidation of membrane proteins and functional activity of band 3 in human red cell senescence.

    abstract：:The state of oxidation of membrane proteins was analyzed in red cell subpopulations of different age by quantifying the oxidation of methionine to its sulfoxide and by determining the amount of thiol groups in ghost membrane preparations and the reactivity of thiols of individual membrane proteins in intact cells. The...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/s0167-4943(05)80010-x

    authors： Castellana MA,Piccinini G,Minetti G,Seppi C,Balduini C,Brovelli A

    更新日期：1992-01-01 00:00:00

  • A multidimensional approach to the assessment of clinical validity in a study on CCVD treatment: dihydroergocristine versus placebo.

    abstract：:An example of multidimensional assessment procedure applied to the study of treatment effects in a type of pathological aging is presented in this paper. Data discussed here come from a clinical trial performed to evaluate the effects of an ergot derivate, dihydroergocristine, in CCVD memory deficits. The multidimensi...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 临床试验,杂志文章

    doi：10.1016/0167-4943(87)90041-0

    authors： Fioravanti M,Buckley AE,Agnoli A

    更新日期：1987-04-01 00:00:00

  • Implication of the G145C polymorphism (rs713598) of the TAS2r38 gene on food consumption by Brazilian older women.

    abstract：:To evaluate the capacity to perceive bitter taste in a sample of the elderly population of the Brazilian Federal District, and to investigate its association with the consumption profile of distinct food groups. A total of 255 female outpatients aged 60 years or older took part in this cross-sectional study. The follo...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2011.05.019

    authors： Colares-Bento FC,Souza VC,Toledo JO,Moraes CF,Alho CS,Lima RM,Cordova C,Nobrega OT

    更新日期：2012-03-01 00:00:00

  • Carotid sinus syncope: the most frequent neurally mediated syncope in the elderly.

    abstract：:The present work reviews current literature and the authors' experience of carotid sinus syndrome (CSS), which is considered to be the most common cause of neurally mediated acute disorders of consciousness in the elderly. Although no definitive consensus about its nosology has yet been reached, most groups agree that...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(94)00599-3

    authors： Menozzi C,Brignole M,Tomasi C,Lolli G,Bottoni N,Oddone D,Gianfranchi L

    更新日期：1995-01-01 00:00:00

  • Effectiveness of exercise with or without thermal therapy for community-dwelling elderly Japanese women with non-specific knee pain: a randomized controlled trial.

    abstract：UNLABELLED:Knee pain is a common health problem in the elderly population, for which non-invasive treatments are recommended as a first line treatment in the management of knee pain. A randomized controlled trial was conducted to determine the effects of exercise with or without thermal therapy in community-dwelling el...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.archger.2013.06.008

    authors： Kim H,Suzuki T,Saito K,Kim M,Kojima N,Ishizaki T,Yamashiro Y,Hosoi E,Yoshida H

    更新日期：2013-11-01 00:00:00

  • A neural network study of the correlation between metabolic-cardiovascular diseases and disability in elderly people.

    abstract：:Numerous studies have affirmed the existence of a correlation between various cardiovascular diseases and functional decline in elderly people. Not much information, however, is available concerning the overall effect of various, possibly coexisting, cardiovascular pathologies, or metabolic conditions notoriously rela...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/s0167-4943(00)00085-6

    authors： Cacciafesta M,Campana F,Trani I I,Annichiarico R,Leonetti-Luparini R,Gianni W,Cicconetti P,Piccirillo G

    更新日期：2000-12-01 00:00:00

  • Walking ability, anxiety and depression, significantly decrease EuroQol 5-Dimension 5-Level scores in older hemodialysis patients in Japan.

    abstract：BACKGROUND:Hemodialysis patients in Japan are aging, but the influence of lifestyle factors on EuroQoL 5-Dimension 5-Level (EQ-5D-5 L) scores in older hemodialysis patients is unclear. This study aimed to measure health-related quality of life using the EQ-5D-5 L for older hemodialysis patients and to identify the life...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章,评审

    doi：10.1016/j.archger.2018.06.006

    authors： Shimizu U,Aoki H,Sakagami M,Akazawa K

    更新日期：2018-01-01 00:00:00

  • Executive function as a mediating factor between visual acuity and postural stability in cognitively healthy adults and adults with Alzheimer's dementia.

    abstract：BACKGROUND:Falls in older adults, notably those with Alzheimer's dementia (AD), are prevalent. Vision and balance impairments are prominent falls risk factors in older adults. However, recent literature in the cognitively impaired suggests that executive function (EF) is important for falls risk assessments. The study ...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2020.104078

    authors： Hunter SW,Divine A,Madou E,Omana H,Hill KD,Johnson AM,Holmes JD,Wittich W

    更新日期：2020-01-01 00:00:00

  • Multidimensional evaluation in a group of centenarians.

    abstract：:A group of 40 Calabrian centenarians (12 males, 28 females) was studied from June 1 to December 31, 1993. Their age was ranging from 100 to 107 years (mean age: 102.3 +/- 1.8 years). Clinical evaluation was performed by recording anamnestic data, an objective examination, and by assessing cognitive performance, emotio...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(96)86965-2

    authors： Infusino P,Mercurio M,Galasso MA,Gareri P,Filardi A,Lacava R,Pansini L,Mattace R

    更新日期：1996-01-01 00:00:00

  • Preferences and frequencies of visits to public facilities in old age--a pilot study in a Swedish town center.

    abstract：:In societies with an increasing proportion of elderly active people it is valuable to gain knowledge about what elderly people actually do and want to do in relation to activity arenas in the public environment. The main aim of this study was to investigate elderly people's preferences and frequencies of visits to pub...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2004.05.010

    authors： Valdemarsson M,Jernryd E,Iwarsson S

    更新日期：2005-01-01 00:00:00

  • Ultrasound measurement of rectus femoris muscle thickness as a quick screening test for sarcopenia assessment.

    abstract：INTRODUCTION:Sarcopenia is a geriatric syndrome related to loss of muscle mass and function, leading to disability, frailty and higher mortality. According to European Working Group on Sarcopenia in Older People (EWGSOP) the diagnosis of sarcopenia requires the assessment of muscle mass, muscle force and function, that...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2019.03.021

    authors： Rustani K,Kundisova L,Capecchi PL,Nante N,Bicchi M

    更新日期：2019-01-01 00:00:00

  • Loss of water from heart muscle cells during aging of rats as measured by X-ray microanalysis.

    abstract：:Age-dependent changes of the intracellular water content (IWC) of the rat myocardium have been measured by X-ray microanalysis of deep-frozen bulk specimens (Zs.-Nagy et al., 1982), using a slow warming up and drying of a very superficial layer of the sample, in order to minimize space charging effects. These results ...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(86)90030-0

    authors： Von Zglinicki T,Lustyik G

    更新日期：1986-12-01 00:00:00

  • Use of COOP charts in the day hospital.

    abstract：:The day hospital is an essential component of health service provision for the elderly. Demonstrating out-come improvement has not been uniformly successful. COOP charts have been validated in general practice as a tool to demonstrate improvement in functional activity. Therefore the aim of this study was to examine t...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/s0167-4943(97)00036-8

    authors： Kinirons MT,Weston B,Rai GS

    更新日期：1998-03-01 00:00:00

  • Changes in glucose turnover parameters during muscular exercise: role of age.

    abstract：:In a study of ten young and seven elderly healthy men we have performed an oral glucose tolerance test (75 g) and employed a euglycemic hyperinsulinemic (0.25 mUx kg/min) glucose clamp technique in order to determine insulin sensitivity. This latter experimental protocol consisted of 120 min of euglycemic clamp follow...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(90)90026-3

    authors： Paolisso G,Cennamo G,Gentile S,Verza M,Varricchio M

    更新日期：1990-05-01 00:00:00

  • Training older adults on Theory of Mind (ToM): transfer on metamemory.

    abstract：BACKGROUND:Research on aging has shown a significant decline in ToM after 65 years of age. Despite these age-related difficulties, no study has yet investigated the possibility to improve ToM in older adults. To address this gap we tested the efficacy of a conversation-based ToM training with age-appropriate ToM tasks ...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2014.10.001

    authors： Lecce S,Bottiroli S,Bianco F,Rosi A,Cavallini E

    更新日期：2015-01-01 00:00:00

  • The influence of winter and summer seasons on physical fitness in aged population.

    abstract：:Epidemiological studies have described the association between physical fitness and health. Few have reported the impact of seasonal variation on fitness determinants, in elderly. We investigated the effects of summer and winter environmental conditions on physical fitness, in both exercise and non-exercise elders. 37...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2018.02.008

    authors： Bezerra P,Rodrigues LP,Ayan C,Cancela JM

    更新日期：2018-01-01 00:00:00

  • Comparison of epicardial adipose tissue (EAT) thickness and anthropometric measurements in metabolic syndrome (MS) cases above and under the age of 65.

    abstract：:EAT is a new index of cardiac and visceral obesity. Waist circumference (WC) measurement is not fully reliable in the determination of visceral adipose tissue (VAT), especially in elderly individuals. Studies on the reflection of the intra-abdominal fat mass by the EAT mass surrounding the heart were performed. Our pu...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.archger.2010.06.016

    authors： Karadag B,Ozulu B,Ozturk FY,Oztekin E,Sener N,Altuntas Y

    更新日期：2011-03-01 00:00:00

  • Association between bisphosphonate therapy and outcomes from rehabilitation in older people.

    abstract：BACKGROUND:Bisphosphonate therapy may have actions beyond bone, including effects on cardiovascular, immune and muscle function. We tested whether bisphosphonate treatment is associated with improved outcomes in older people undergoing inpatient rehabilitation. METHODS:Analysis of prospectively collected, linked routi...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2017.01.017

    authors： Goodbrand JA,Hughes LD,Cochrane L,Donnan PT,McGilchrist M,Frost H,McMurdo ME,Witham MD

    更新日期：2017-01-01 00:00:00

  • Verification of the membrane hypothesis of aging on the identified giant neurons of the snail Lymnaea stagnalis L. (Gastropoda, Pulmonata) by a combined application of intracellular electrophysiology and X-ray microanalysis.

    abstract：:The validity of the membrane hypothesis of aging (Zs.-Nagy, 1978) was tested on identified giant neurons of the snail Lymnaea stagnalis L. by using a combination of intracellular microelectrophysiology and X-ray microanalysis of the intracellular water and electrolyte concentrations on the very same cells. The snails ...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(85)90018-4

    authors： Nagy I,Tóth S,Lustyik G

    更新日期：1985-04-01 00:00:00

  • Amantadine infusions in mild dementia: acute double-blind placebo-controlled EEG mapping and psychometric studies.

    abstract：:In a double-blind, placebo-controlled study, the acute central effects of amantadine infusions (200 mg for 1 h) were studied in 20 mildly demented patients (DSM-III-R) utilizing EEG mapping as well as psychometry and psychophysiology at the hours 0, 2, 4, 6 and 8. Multivariate analysis of the EEG demonstrated a signif...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 临床试验,杂志文章

    doi：10.1016/0167-4943(92)90039-7

    authors： Saletu B,Anderer P,Semlitsch HV,Grünberger J,Linzmayer L,Chaudhry HR

    更新日期：1992-07-01 00:00:00

  • Gender differences in cognitive impairment and mobility disability in old age: a cross-sectional study in Ouagadougou, Burkina Faso.

    abstract：:This study aims to examine differences in cognitive impairment and mobility disability between older men and women in Ouagadougou, Burkina Faso, and to assess the extent to which these differences could be attributable to gender inequalities in life course social and health conditions. Data were collected on 981 men a...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2013.06.007

    authors： Onadja Y,Atchessi N,Soura BA,Rossier C,Zunzunegui MV

    更新日期：2013-11-01 00:00:00

  • Cumulative effects of cognitive impairment and frailty on functional decline, falls and hospitalization: A four-year follow-up study with older adults.

    abstract：OBJECTIVE:Evaluate the cumulative effects of cognitive impairment and frailty on functional decline, falls and hospitalization in older adults over a four-year period. METHOD:Four hundred five older adults (60-95 years; mean age: 70.62 ± 7.12 years), 57 % female. The frailty evaluation was performed using the clinical...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2019.104005

    authors： Brigola AG,Ottaviani AC,Alexandre TDS,Luchesi BM,Pavarini SCI

    更新日期：2020-01-01 00:00:00

  • Interaction of central obesity and sarcopenia on nutritional status in the community-dwelling older people.

    abstract：OBJECTIVES:To investigate the interrelationships between central obesity, sarcopenia and nutritional status in the elderly. METHODS:We enrolled 501 elderly (women: 47.5 %) with complete datasets. Biochemical and anthropometric data were measured after an overnight fast. Basic characteristics, psychosocial and behavior...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2019.104003

    authors： Chang CS,Chang YF,Liu PY,Wu SJ,Chiu CJ,Chen CY,Wu CH

    更新日期：2020-01-01 00:00:00

  • Frailty and heart response to physical activity.

    abstract：BACKGROUND:Although previous studies showed that frail older adults are more susceptible to develop cardiovascular diseases, the underlying effect of frailty on heart rate dynamics is still unclear. The goal of the current study was to measure heart rate changes due to normal speed and rapid walking among non-frail and...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2020.104323

    authors： Toosizadeh N,Ehsani H,Parthasarathy S,Carpenter B,Ruberto K,Mohler J,Parvaneh S

    更新日期：2020-12-11 00:00:00

  • Trends and determinants of informal and formal caregiving in the community for disabled elderly people in Taiwan.

    abstract：:Although family caregiving for elderly people has been the backbone of long-term care in Taiwan, it is not clear whether informal help from family members has diminished in recent years due to changes in social structure and traditions. The objective of this study is to examine the trend and the factors influencing th...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2012.11.005

    authors： Ku LJ,Liu LF,Wen MJ

    更新日期：2013-03-01 00:00:00

  • Depression and subjective economy among elderly people in Asian communities: Japan, Taiwan, and Korea.

    abstract：:The objective of this study is to investigate the cross-cultural relationship between depressive state and subjective economic status, as well as subjective quality of life (QOL) and activities of daily living (ADL) among elderly people in communities in Japan, Taiwan, and Korea. We studied 595 subjects aged 65 years ...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/j.archger.2014.11.003

    authors： Imai H,Chen WL,Fukutomi E,Okumiya K,Wada T,Sakamoto R,Fujisawa M,Ishimoto Y,Kimura Y,Chang CM,Matsubayashi K

    更新日期：2015-03-01 00:00:00

  • Effects of chronic codergocrine mesylate administration on the brain somatostatinergic system in aged rats.

    abstract：:Codergocrine mesylate (dihydroergotoxine; DHET), which is an ergot derivative, has been reported to counteract some age-induced impairments in brain function, but the mechanism of these effects is not known. We examined the effect of chronic DHET administration on the somatostatinergic system in the brains of aged rat...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(92)90013-t

    authors： Tanaka K,Ogawa N,Asanuma M,Hirata H,Kondo Y,Chou HH,Mori A

    更新日期：1992-09-01 00:00:00

  • Associations of various perceived-stress situations with depressive symptoms in ≥50-year old Taiwanese men and women: Results from the Taiwan Longitudinal Study on Aging.

    abstract：:This study was aimed to evaluate the cross-sectional and longitudinal associations between various perceived-stress and depressive symptoms in old Taiwanese men and women aged 50 years and over. Data were derived from the Taiwan Longitudinal Study on Aging. Stress for health, finance, and family members' related issue...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.archger.2016.07.003

    authors： Tsai HJ,Chang FK

    更新日期：2016-11-01 00:00:00

  • Gene expressions of cholecystokinin (CCK) and CCK receptors, and its satiety effect in young and old male rats.

    abstract：:Cholecystokinin (CCK), one of the first discovered gastrointestinal hormones, which stimulates pancreatic enzyme secretion and induces gallbladder contraction, is one of the most abundant neurotransmitter peptides in the brain and is implicated in satiety via CCK-A receptors. We compared the suppressive effect of cent...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/0167-4943(95)00634-w

    authors： Miyasaka K,Kanai S,Masuda M,Ohta M,Kawanami T,Matsumoto M,Funakoshi A

    更新日期：1995-09-01 00:00:00

  • Neurochemical parameters of the main neurotransmission systems in aging mice.

    abstract：:The present work was designed to study the effect of aging on some parameters of the glutamatergic, aminergic and cholinergic neurotransmission, in the main brain areas of mice of the long-surviving BALB/c-nu strain. We have assayed: (1) the density of three ionotropic receptors for excitatory aminoacids (EAA) which s...

    journal_title：Archives of gerontology and geriatrics

    pub_type： 杂志文章

    doi：10.1016/s0167-4943(00)00057-1

    authors： Magnone MC,Rossolini G,Piantanelli L,Migani P

    更新日期：2000-06-01 00:00:00