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Magnetic resonance imaging of carotid plaque inflammation in acute coronary syndromes: a sign of multisite plaque activation.

Abstract：

:Widespread plaque inflammation has been demonstrated in acute coronary syndromes (ACS). We evaluated signs of plaque inflammation in carotid arteries of patients with ACS by contrast-enhanced magnetic resonance imaging (MRI). Carotid MRI was performed in 13 patients with ACS and in 9 controls having at least 1 carotid plaque with a stenosis > or =40%. MRI criteria of plaque inflammation were: increased T2 signal >50% of the plaque areas (tissue oedema) and/or enhancement after gadolinium injection (neo-vascularization). MRI signs of inflammation were found in 95% and in 33% of patients with ACS and controls, respectively (p<0.001). Carotid artery MRI may serve as a window to the entire cardiovascular system, to identify "vulnerable" patients.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Lombardo A,Rizzello V,Natale L,Lombardi M,Coli S,Snider F,Bonomo L,Crea F

doi

10.1016/j.ijcard.2008.03.077

subject

Has Abstract

pub_date

2009-07-24 00:00:00

pages

103-5

issue

1

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(08)00551-2

journal_volume

136

pub_type

信件

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