Abstract:
:Since publication of the seventh American College of Chest Physicians (ACCP) supplement on antithrombotic and thrombolytic therapy, the results of clinical trials have provided important new information on the management of thromboembolic disorders, and the science of developing recommendations has advanced. In the accompanying supplement, we provide the new and updated recommendations and review several important changes that we have made in our guideline development process. We again made a conscious effort to increase the participation of female authors and contributors from outside North America, the latter reflecting the widespread use and dissemination of these guidelines internationally. The grading system for the recommendations was adopted in 2006 by the ACCP for all its guidelines, is similar to the increasingly widely used Grades of Recommendation, Assessment, Development, and Evaluation approach, and is described in detail in one of the introductory chapters. While most of the evidence on which recommendations are made remains low quality in fields of pediatric thrombosis, thrombosis in pregnancy, and thrombosis in valvular heart disease, rigorous studies in other fields have resulted in new and strong evidence-based recommendations for many indications.
journal_name
Chestjournal_title
Chestauthors
Hirsh J,Guyatt G,Albers GW,Harrington R,Schünemann HJdoi
10.1378/chest.08-0652subject
Has Abstractpub_date
2008-06-01 00:00:00pages
110S-112Sissue
6 Suppleissn
0012-3692issn
1931-3543pii
S0012-3692(08)60112-9journal_volume
133pub_type
杂志文章,实务指引相关文献
CHEST文献大全abstract:STUDY OBJECTIVES:To characterize the prevalence of undiagnosed pulmonary hypertension in patients with limited and diffuse scleroderma. DESIGN:Prospective cross-sectional study. SETTING:University-based outpatient clinic. PATIENTS:Thirty-four consecutive patients with limited (n = 29) or diffuse (n = 5) scleroderma ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.6.1515
更新日期:1996-12-01 00:00:00
abstract::Twenty-one patients presenting with extrapulmonary sarcoidosis, 20 patients with pulmonary sarcoidosis, and 12 healthy volunteers were investigated. They were evaluated for roentgenographic findings, as well as for immunologic marker expression of cells in bronchoalveolar lavage (BAL) fluid. The patients presenting wi...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.94.1.115
更新日期:1988-07-01 00:00:00
abstract::We report a case of pleural dissemination of invasive thymoma, which was successfully treated with intrathoracic chemothermotherapy following panpleuropneumonectomy. Intrathoracic chemothermotherapy in combination with surgery may be a hopeful adjuvant treatment to control pleural disseminated lesions of invasive thym...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.105.6.1884
更新日期:1994-06-01 00:00:00
abstract::A newborn infant with severe respiratory distress from bilateral diaphragmatic paralysis caused by birth injury was successfully treated with nasal continuous positive airway pressure (CPAP). Improvement gradually occurred, and CPAP was discontinued after he was 23 days of age. This therapy has advantages over alterna...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.75.3.392
更新日期:1979-03-01 00:00:00
abstract:BACKGROUND:Empirical therapy has been recommended as an initial clinical approach for treating gastroesophageal reflux-induced chronic cough (GERC). This study compared the predictive accuracy of the Gastroesophageal Reflux Disease Questionnaire (GerdQ) with the accuracy of multichannel intraluminal impedance pH monito...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-1634
更新日期:2014-06-01 00:00:00
abstract::Targeted temperature management (TTM) has been investigated experimentally and used clinically for over 100 years. The initial rationale for the clinical application of TTM, historically referred to as therapeutic hypothermia, was to decrease the metabolic rate, allowing the injured brain time to heal. Subsequent rese...
journal_title:Chest
pub_type: 历史文章,杂志文章,评审
doi:10.1378/chest.12-3025
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Dynamic hyperinflation (DH) develops in patients with COPD during incremental exercise with a cycle ergometer. The aims of this study were to determine whether DH can be evidenced after walking with a handheld spirometer and to determine its functional consequences. METHODS:Fifty patients with COPD (39 men;...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.09-0410
更新日期:2009-12-01 00:00:00
abstract::Postoperative bronchial stump failure is a life-threatening complication, and several surgical approaches and procedures have been developed to close the stump. In this report, we describe a case of left mainstem bronchial stump diastasis after pneumonectomy for lung cancer, in which the bronchial stump was re-closed ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.117.3.884
更新日期:2000-03-01 00:00:00
abstract::A 77-year-old man with a history of renal cell carcinoma presented with orthostatic syncope. Investigation revealed metastatic carcinoma in the left lung extending through the pulmonary veins into the left atrium obstructing the mitral orifice. On review of the literature, this case appears to be the first to describe...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.98.2.481
更新日期:1990-08-01 00:00:00
abstract::We assessed the importance of Streptococcus pneumoniae and immunologic response to 14-valent pneumococcal vaccine in a randomized (saline placebo or vaccine) double-blind pilot study involving 103 patients with chronic obstructive pulmonary disease (COPD). Antibody titers, the flora of the sputum, respiratory infectio...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.92.2.204
更新日期:1987-08-01 00:00:00
abstract::To determine whether sectional development in pulmonary and critical care medicine influences medical house officers' (HO) interests and knowledge about respiratory medicine, we reviewed HO performance on the American Board of Internal Medicine (ABIM) certifying examination during 4 years before and 5 years after reor...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.110.2.533
更新日期:1996-08-01 00:00:00
abstract:BACKGROUND:Interstitial lung disease (ILD) results in high morbidity and health-care utilization. Diagnostic delays remain common and often occur in nonpulmonology settings. Screening for ILD in these settings has the potential to reduce diagnostic delays and improve patient outcomes. RESEARCH QUESTION:This study soug...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2020.02.044
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Epidemiologic investigations of acute lung injury (ALI) and ARDS have focused on mechanically ventilated patients in ICUs, and have reported high mortality rates. We sought to determine the incidence and lethality of these syndromes in the respiratory isolation areas of general wards, a non-ICU setting that ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.08-0280
更新日期:2009-02-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the safety and efficacy of additional minocycline pleurodesis after thoracoscopic treatment of primary spontaneous pneumothorax. DESIGN:Retrospective comparative study with a historical control. SETTING:Thoracic surgical division of a university-affiliated tertiary medical center. PATIENT...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.1.50
更新日期:2004-01-01 00:00:00
abstract::Following an outline that details the pathogens causing community-acquired pneumonia (CAP) identified in studies from Europe, this article reviews the guidelines for the management of CAP in four European countries--France, Italy, Spain, and the United Kingdom. The method behind the development of each document is des...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.113.3_supplement.183s
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Central sleep apnea (CSA) is common among patients with heart failure (HF) and is promoted by elevated CO2 chemosensitivity. Left atrial size is a marker of the hemodynamic severity of HF. The aim of this study was to determine if left atrial size predicts chemosensitivity to CO2 and CSA in patients with HF....
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.13-0309
更新日期:2014-07-01 00:00:00
abstract::There are many complementary techniques for mediastinal staging of lung cancer. It is increasingly apparent that the accuracy of mediastinal staging depends not only on which test is used but also on technical factors of how the procedure is performed. This article reviews data regarding such technical factors and pro...
journal_title:Chest
pub_type: 杂志文章,评审
doi:10.1378/chest.09-1378
更新日期:2010-02-01 00:00:00
abstract:STUDY OBJECTIVE:Laboratory testing plays a minor role in the assessment of aortic dissection. Its main value is in the exclusion of other diseases. Following an incidental observation, we systematically investigated the relationship between elevated d-dimer levels and acute aortic dissection. DESIGN:We prospectively t...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.123.5.1375
更新日期:2003-05-01 00:00:00
abstract::Twenty-two consecutive patients underwent esophageal stimulation and recording for the diagnosis and management of supraventricular tachycardia. In 13 of these patients, the resting electrocardiogram was normal and in nine it showed pre-excitation. Of the 13 patients with a normal resting electrocardiogram, supraventr...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.93.2.339
更新日期:1988-02-01 00:00:00
abstract:STUDY OBJECTIVES:The purpose of this study was to determine the impact of a multisite implementation of an evidence-based clinical practice guideline for bronchiolitis. DESIGN:Before and after study. SETTING:Eleven Child Health Accountability Initiative (CHAI) study hospitals. PATIENTS:Children < 12 months of age wi...
journal_title:Chest
pub_type: 杂志文章,多中心研究
doi:10.1378/chest.121.6.1789
更新日期:2002-06-01 00:00:00
abstract:STUDY OBJECTIVES:To evaluate, through clinical and transthoracic echocardiography (TTE) follow-up, the natural history of persistent pericardial effusion (PE) after postoperative day 15 in patients who were given and were not given anticoagulant therapy. DESIGN AND PATIENTS:We retrospectively studied a cohort of 1,277...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.125.6.2182
更新日期:2004-06-01 00:00:00
abstract:STUDY OBJECTIVE:Several studies have demonstrated the superiority of salmeterol and formoterol to either regular treatment with albuterol or placebo. However, to date there have been no trials comparing the efficacy of salmeterol and formoterol in patients with severe asthma. DESIGN:We undertook a randomized, placebo-...
journal_title:Chest
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1378/chest.121.5.1401
更新日期:2002-05-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether patients with congestive heart failure who develop Cheyne-Stokes respiration (CSR) during sleep experience excessive daytime sleepiness. This was addressed by comparing sleep quality and daytime sleepiness in three groups: patients with CHF and CSR during sleep (CSR group), patients...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.107.4.952
更新日期:1995-04-01 00:00:00
abstract::OSA has emerged as a highly prevalent public health problem that imposes important mid- and long-term consequences, namely cardiovascular, metabolic, cognitive, and cancer-related alterations. OSA is characterized by increased upper airway resistance, alveolar hypoventilation, and recurrent upper airway obstruction du...
journal_title:Chest
pub_type: 杂志文章
doi:10.1016/j.chest.2018.03.001
更新日期:2018-10-01 00:00:00
abstract:STUDY OBJECTIVES:To determine if persistent airway tissue mast cells are associated with treatment failure when patients discontinue inhaled corticosteroids (ICS). DESIGN:Double-blind, randomized, placebo-controlled trial. SETTING:Multicenter, tertiary referral centers. PATIENTS OR PARTICIPANTS:Forty-five subjects w...
journal_title:Chest
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1378/chest.124.1.42
更新日期:2003-07-01 00:00:00
abstract::Echocardiographic examination in a patient with primary pulmonary hypertension demonstrated midsystolic closure of the aortic valve, which has often been described in hypertrophic cardiomyopathy with or without obstruction, in discrete subaortic stenosis, and in ruptured aneurysm of the right coronary sinus of Valsalv...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.79.6.710
更新日期:1981-06-01 00:00:00
abstract::Fifty-nine patients were studied who had severe tricuspid regurgitation which was confirmed by right ventriculography and during surgery in order to determine the incidence of clinical, radiologic, and hemodynamic clues of severe tricuspid regurgitation. Eighty-eight percent of patients had Carvallo sign alone or in c...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.82.6.726
更新日期:1982-12-01 00:00:00
abstract::Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) can reliably sample enlarged mediastinal lymph nodes in patients with non-small cell lung cancer (NSCLC), and in practice is mostly used to sample nodes visible on CT or positron emission tomography (PET). Few data are available on the use of...
journal_title:Chest
pub_type: 临床试验,杂志文章
doi:10.1378/chest.07-2535
更新日期:2008-04-01 00:00:00
abstract:STUDY OBJECTIVES:Clinical prediction models for the diagnosis of obstructive sleep apnea (OSA) have lacked the accuracy necessary to confidently replace polysomnography (PSG). Artificial neural networks are computer programs that can be trained to predict outcomes based on experience. This study was conducted to test t...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.116.2.409
更新日期:1999-08-01 00:00:00
abstract::Results of studies that use laboratory tests are often easy to interpret, because we are familiar with the units and how to interpret them. However, this is not the case when the results are presented as ORs, relative risks, correlation, or scores on an unfamiliar scale. This article explains these various indices of ...
journal_title:Chest
pub_type: 杂志文章
doi:10.1378/chest.11-2473
更新日期:2012-03-01 00:00:00