Abstract:
:Fever of unknown origin (FUO) is a common presentation for patients with advanced human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). We prospectively followed 72 patients, consecutively admitted to a Thai regional hospital with FUO and HIV infection to identify aetiologies and mortality in the era of available antiretroviral therapy (ART). Aetiologies of FUO were identified in 67 patients (93%), of whom 61(85%) had an infectious aetiology. The most common infectious aetiologies were Mycobacterium tuberculosis (n=30; 42%), Cryptococcus neoformans (n=17; 24%), Pneumocystis jiroveci (n=9; 13%), Toxoplasma gondii (n=5; 7%), and salmonella bacteraemia (n=5; 7%). Nineteen patients (26%) had co-infection with two or more pathogens. The median CD4 count was 120 cells/mm(3) (range, 1-581 cells/mm(3)), and the all-cause mortality was 22% (n=16). By multivariate analysis, inadequate antimicrobial treatment was the sole predictor of mortality (aOR=4.9; 95% CI=1.2-21.9; P=0.02). Overall, 58 of 72 patients (81%) had an opportunistic infection suggesting that guideline use of ART and prophylactic strategies remain unmet needs that will benefit individuals and populations with HIV/AIDS in Thailand.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Kitkungvan D,Apisarnthanarak A,Plengpart P,Mundy LMdoi
10.1258/ijsa.2007.007191subject
Has Abstractpub_date
2008-04-01 00:00:00pages
232-5issue
4eissn
0956-4624issn
1758-1052pii
19/4/232journal_volume
19pub_type
杂志文章abstract::We report a case of cutaneous penile tuberculosis (TB) in an HIV-positive man masquerading as a sexually transmitted infection. This case details a patient who was diagnosed with HIV and achieved virological suppression on antiretroviral therapy. He subsequently stopped his therapy and travelled to a TB-endemic area. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012103
更新日期:2013-01-01 00:00:00
abstract::We describe the case of a young girl with vertically-transmitted HIV infection who presented with chronic ocular inflammation characterized by several relapses and remissions. Good viral and immunological status made infective or neoplastic causes unlikely; the diagnosis was challenging and finally spontaneous remissi...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416629263
更新日期:2016-10-01 00:00:00
abstract::Individuals with substance use disorders (SUDs) are at higher risk of HIV infection, yet recent studies show rates of HIV testing are low among this population. We implemented and evaluated a nurse-initiated HIV oral rapid testing (NRT) strategy at three Veterans Health Administration SUD clinics. Implementation of NR...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2012.012050
更新日期:2012-11-01 00:00:00
abstract::The objectives of this study were to determine the prevalence of and factors associated with prenatal HIV screening and the availability of HIV test results in medical records in Pittsburgh, PA, USA. Three hundred postpartum women were surveyed about demographics and prenatal care provider(s) and practice setting and ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.010200
更新日期:2011-04-01 00:00:00
abstract::Syphilis rates have been increasing in men who have sex with men (MSM) in London. To describe risk behaviour and refine public health interventions, we conducted prospective enhanced surveillance of new syphilis cases in MSM attending selected London sexual health clinics (SHCs) between October 2016 and January 2017. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462418814998
更新日期:2019-04-01 00:00:00
abstract::The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462420906998
更新日期:2020-07-01 00:00:00
abstract::The completeness of a 'first consultation' human immunodeficiency virus (HIV) clinical history before and after the introduction of an HIV proforma was audited by a retrospective case notes review. Twenty key variables considered essential to every history were assessed. There was a significant improvement in the docu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2007.007174
更新日期:2008-02-01 00:00:00
abstract::We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provide...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416641813
更新日期:2016-08-01 00:00:00
abstract::The aim of the study was to determine in a rural population the age- and sex-specific prevalence and incidence rates of serological reactivity of 5 common sexually transmitted diseases (STDs) and their association with HIV-1 antibody status. Of the adult population of two villages (529 adults aged 15 years or more) 29...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/095646249400500509
更新日期:1994-09-01 00:00:00
abstract::Seventy-two blood donors who were tested positive by the Singapore Blood Transfusion Service (SBTS) for Treponema pallidum haemagglutination (TPHA) test, were evaluated at the Department of Sexually Transmitted Diseases Clinic (DSC) between November 1994 to December 1996. All underwent syphilis serological testing, in...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462971919237
更新日期:1997-12-01 00:00:00
abstract::A 41-year-old HIV-positive man who has sex with men (MSM) with a family history of deep vein thrombosis (DVT) presented to the emergency department with an acutely swollen lower limb. The initial clinical diagnosis was of a possible DVT and the patient was anticoagulated. However, investigations subsequently excluded ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011217
更新日期:2012-03-01 00:00:00
abstract::Tetracycline resistant Neisseria gonorrhoeae (TRNG) contain a 25.2 MDa TetM plasmid encoding a 68 KDa cytoplasmic protein which confers high-level tetracycline resistance. The aim of this study was to subtype all TRNG isolated in Scotland between 1992 and 1998. Subtyping was performed by a polymerase chain reaction (P...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462991913204
更新日期:1999-10-01 00:00:00
abstract::Psoriasis is a prevalent systemic immune-mediated disease with cutaneous manifestations. In HIV-infected patients, psoriasis may have a higher incidence, present atypical and more exuberant clinical features, and is frequently recalcitrant to treatment. Despite this aggravated severity, treatment options for psoriasis...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,评审
doi:10.1177/0956462419827673
更新日期:2019-05-01 00:00:00
abstract::The goal of this study was to develop an evaluation method of antiretroviral treatment adherence from a hospital pharmacy and to identify one or more factors that influenced this adherence, such as patient or treatment characteristics. The HIV patients included in this study were based, for the major part, in Saint-An...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462053888826
更新日期:2005-05-01 00:00:00
abstract::The aim of the work is to describe the occurrence of ocular complications and loss of vision due to herpes zoster ophthalmicus (HZO) in HIV-positive patients who received early antiviral therapy for HZO.This is a post hoc analysis of prospectively collected data.Twenty-four HIV-positive patients with HZO were included...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462412472303
更新日期:2013-02-01 00:00:00
abstract::Antioxidants significantly inhibit oxidative processes. The study seeks to determine the activity of endogenous antioxidants and CD4+ T-cell expression in HIV-serodiscordant-heterosexual partners. The case-control study had the following groups; A- (13 serodiscordant-seronegative subjects), B- (13 serodiscordant-serop...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2008.008031
更新日期:2008-08-01 00:00:00
abstract::Sexually transmitted diseases (STDs) continue to be the most common notifiable infectious conditions worldwide. Their unacceptably high incidence is underlined by the recent emergence of a (presently) incurable and lethal STD--human immunodeficiency virus (HIV) infection--which merits its description as a pandemic, an...
journal_title:International journal of STD & AIDS
pub_type: 社论,评审
doi:10.1258/0956462961918419
更新日期:1996-11-01 00:00:00
abstract::In order to determine inpatient hospital mortality rates, causes of mortality and characteristics of inpatients at Kamuzu Central Hospital (KCH) in Lilongwe, Malawi, we conducted a prospective observational study of all patients admitted to KCH medical ward from 20 September 2008 to April 2, 2009. All admission diagno...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/ijsa.2011.011021
更新日期:2011-08-01 00:00:00
abstract::Our objective was to determine the prevalence of HIV and the distribution of HIV-related diseases among adult, medical inpatients. Consecutive admissions were recruited and a single ELISA assay was used to determine HIV infection. Demographic and clinical details were extracted from clinical records. Of 507 patients, ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923336
更新日期:2001-06-01 00:00:00
abstract::Implementation of the National Chlamydia Screening Programme in Cornwall commenced in April 2003. Initially, women in community venues were screened using urine samples. However, many of these urine samples were inhibitory to polymerase chain reaction (PCR), resulting in a high recall rate for women in the programme. ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207779949619
更新日期:2007-02-01 00:00:00
abstract::A heterosexual man with acquired syphilis had an uncommon presentation in the form of acute visual loss. The unusual clinical presentation and a high cerebrospinal fluid lymphocyte count led to delayed diagnosis and treatment. Recognition of uncommon presentation of syphilis in the current epidemic is essential for th...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/095646207781024847
更新日期:2007-06-01 00:00:00
abstract::We report a case of human herpes virus-8-associated multicentric Castleman's disease in an HIV-positive patient with hyponatraemia. A 65-year-old man was admitted with relapsing and remitting fever, scattered skin eruptions and hepatosplenomegaly following combination antiretroviral therapy for his HIV infection. Base...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462414562050
更新日期:2015-10-01 00:00:00
abstract::This study aimed to describe the quality and costs of sexually transmitted disease (STD) case management in urban pharmacies in The Gambia, and explore pharmacy workers' (PWs) willingness to improve the STD care they provide. PWs from 24 registered pharmacies were interviewed in order to collect information on their k...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923471
更新日期:2001-07-01 00:00:00
abstract::In recognition of the increasing number of HIV-infected young people attending the HIV department at a district general hospital, a case note review was conducted. There was a high prevalence of psychosocial problems and medical complexity among this cohort. As a result, tailored young persons' services were developed...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462413486453
更新日期:2013-11-01 00:00:00
abstract::This study examines the use of various direct observation therapy-HAART treatment support modalities in Jos, Nigeria. A 12-month observational study enrolling 175 antiretroviral naïve patients into four arms of direct observation therapy-HAART (highly active antiretroviral therapy); daily observed therapy (DOT), twice...
journal_title:International journal of STD & AIDS
pub_type: 临床试验,杂志文章
doi:10.1258/095646207782212252
更新日期:2007-11-01 00:00:00
abstract::In the ARTEMIS trial, 689 treatment-naïve, HIV-1-infected adults received darunavir/ritonavir (DRV/r) 800/100 mg every day or lopinavir/ritonavir (LPV/r) 800/200 mg total daily dose plus fixed-dose tenofovir/emtricitabine. Week 96 metabolic parameters are reported. Adverse events (AEs) classed as metabolism/nutrition ...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章,随机对照试验
doi:10.1258/ijsa.2012.012120
更新日期:2013-01-01 00:00:00
abstract::A questionnaire survey and case notes audit reviewing management of epididymo-orchitis (E-O) by 34 Genitourinary Medicine (GUM) clinics located in the North Thames was undertaken. Twenty-two clinics (65%) returned completed questionnaires and audited a total of 83 newly diagnosed cases. All participating clinics offer...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462011923066
更新日期:2001-05-01 00:00:00
abstract::Scolecobasidium sp. are commensal soil and water thermophilic dematiaceous fungi. They are commonly isolated as contaminants from respiratory secretions due to their abundant presence in water supplies, but they are also rare yet emerging culprits producing severe opportunistic infections in immunocompromised individu...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416646688
更新日期:2017-01-01 00:00:00
abstract::The purpose of this study was to examine, among 2 groups of individuals with different risk profiles, the similarity of their attitudes towards vaccines for sexually transmitted diseases (STDs) and non-STDs. Subjects were recruited from an undergraduate psychology class at an urban university (n=518) or were participa...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1258/0956462001915624
更新日期:2000-03-01 00:00:00
abstract::HIV status awareness is key to prevention, linkage-to-care and treatment. Our study evaluated the accessibility and potential willingness of HIV self-testing among men who have sex with men (MSM) and transgender women in Peru. We surveyed four pharmacy chains in Peru to ascertain the commercial availability of the ora...
journal_title:International journal of STD & AIDS
pub_type: 杂志文章
doi:10.1177/0956462416630674
更新日期:2017-02-01 00:00:00