Abstract：
:Tetracycline resistant Neisseria gonorrhoeae (TRNG) contain a 25.2 MDa TetM plasmid encoding a 68 KDa cytoplasmic protein which confers high-level tetracycline resistance. The aim of this study was to subtype all TRNG isolated in Scotland between 1992 and 1998. Subtyping was performed by a polymerase chain reaction (PCR) assay which characterizes the TetM plasmid as either the Dutch variant (443 base pair product) or the American variant (777 base pair product). Of the 78 TRNG isolates, 35 were the American variant and 43 were the Dutch variant. TRNG were distributed amongst 30 serovar/auxotype classes, the most common being 1A6/NR (11.5%), 1A6/P (14.1%) and 1B4/NR (14.1%). The country where infection was acquired was known for 36 of the 46 TRNG strains isolated between 1996 and 1998. All infections acquired in Asia and South America were the Dutch variant whereas all infections acquired in Africa were the American variant. A penicillinase plasmid was present in 66% (23/35) of the American variant TRNG compared with 51% (22/43) of the Dutch variant: the 3.2 MDa penicillinase plasmid was found in 87% of the American variant TRNG whereas the 4.4 MDa penicillinase plasmid was found in 68% of the Dutch variant TRNG. We conclude that subtyping of TRNG by PCR is a useful tool in studying the epidemiology of gonococcal infection due to plasmid-mediated resistant isolates.
journal_name
Int J STD AIDSjournal_title
International journal of STD & AIDSauthors
Beattie T,Moyes A,Patrizio C,Young Hdoi
10.1258/0956462991913204subject
Has Abstractpub_date
1999-10-01 00:00:00pages
646-51issue
10eissn
0956-4624issn
1758-1052journal_volume
10pub_type
杂志文章abstract：:Cutaneous Candida infections may occur in patients with HIV/AIDS, cancer, receiving chemotherapy and solid organ transplantation. A 32-year-old woman was admitted to the department suffering from pruritic and erythematous plaque on left side of her face for the past two months. The patient was HIV positive, diagnosed ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462413479897
更新日期：2013-09-01 00:00:00
abstract：:Forty asymptomatic HIV-infected individuals with CD4+ lymphocyte levels above 400x10(6)/l were immunized over 5 years with recombinant envelope glycoprotein gp160 (rgp160). After 5 years there was a trend towards more non-progressors in the immunized group as compared to the matched controls. Since immunizations could...
journal_title：International journal of STD & AIDS
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1999-08-01 00:00:00
abstract：:We evaluated Cobas Amplicor, a highly automated polymerase chain reaction (PCR) system, to test first-void urine (FVU) and urethral swab specimens for Chlamydia trachomatis and Neisseria gonorrhoeae in men attending a sexually transmitted infection (STI) clinic. Results were compared against an in-house radioimmune do...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462981921594
更新日期：1998-01-01 00:00:00
abstract：:The aims of this study were to understand the prevalence and correlates of syphilis infection among HIV-positive men who have sex with men (MSM) in Shanghai, China. A total of 200 HIV-positive MSM participants were recruited using "snowball" sampling. Participants were tested for syphilis and completed a one-time ques...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462413512804
更新日期：2014-05-01 00:00:00
abstract：:We describe the first reported case of Candida pelliculosa meningitis in HIV infection. This case highlights the risk of uncommon opportunistic infections in association with the immunocompromised and the importance of autopsy as a diagnostic tool in HIV infection. We discuss the epidemiology, diagnosis and management...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2010.010113
更新日期：2011-01-01 00:00:00
abstract：:As few studies have compared the clinical features of rectal gonorrhoea in men who have sex with men with or without concurrent chlamydial infection, this longitudinal study was undertaken to address this issue. The cohort consisted of 129 men with rectal gonorrhoea, 34 of whom had concurrent chlamydiae. Symptoms of p...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646206777323373
更新日期：2006-06-01 00:00:00
abstract：:The objectives were, first, to determine the sensitivity and specificity of the Osmetech Microbial Analyser (OMA) for the diagnosis of bacterial vaginosis (BV) and, secondly, to determine the factors that interfere with the performance of the test. Women presenting to a genitourinary medicine clinic underwent routine ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646203321156881
更新日期：2003-02-01 00:00:00
abstract：:A national Scottish audit of 282 patients with HIV infection attending 11 clinics showed the following levels of performance against quality improvement Scotland Sexual Health Services Standards: syphilis serology was offered in the previous six months to 55% of patients (range: 12-97% of patients in individual clinic...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2011.011379
更新日期：2012-06-01 00:00:00
abstract：:Self sampling of the secretions of the female genital tract for microbiological investigations for Neisseria gonorrhoeae, Chlamydia trachomatis and Trichomonas vaginalis was assessed in female attenders of the genitourinary medicine clinic in Coventry and Warwickshire Hospital. The purpose of the study was to evaluate...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/095646249400500411
更新日期：1994-07-01 00:00:00
abstract：:Patients who acquire repeated infections of gonorrhoea are well described. A study was undertaken of male patients attending a central London clinic in an attempt to identify features of those acquiring repeated infections to facilitate risk reduction strategies. During the 3 years 1990 to 1992, 18.8% of patients cont...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462961917807
更新日期：1996-07-01 00:00:00
abstract：:Increasing numbers of HIV-infected children are now reaching adulthood and young people account for 10% of new HIV diagnosis in the UK each year. This audit of young people attending specialist and generic HIV services in Inner London in 2006 (n=39) highlights the complex medical and psychosocial needs of this patient...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646207781568565
更新日期：2007-09-01 00:00:00
abstract：:We assessed the validity of a syndromic case management approach for reproductive tract infections (RTIs) among 371 pregnant women attending antenatal care facilities in Kingston, Jamaica, using an algorithm previously validated in high-risk Jamaican women. For our antenatal attenders, the algorithm had low sensitivit...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646204774195209
更新日期：2004-06-01 00:00:00
abstract：:The classical lesion of primary syphilis is a solitary, indurated, painless chancre. Atypical presentations, such as herpetiform ulceration, are well recognized. However, there are few references in the medical literature to primary syphilis presenting as balanitis or balanoposthitis. We report two cases of primary sy...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646207781147346
更新日期：2007-07-01 00:00:00
abstract：:Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is a multisystem disease that can involve the human eyes. Using ophthalmic examination records from January 2006 to November 2015, we retrospectively reviewed all patients who were diagnosed with HIV/AIDS in our hospital. The study was perfor...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462417694569
更新日期：2017-10-01 00:00:00
abstract：:Despite the success of combination antiretroviral therapies, people living with HIV (PLWH) are at an increased risk of developing diverse malignancies, including oral cancer. We here present two cases of PLWH where the early diagnosis of potentially malignant disorders in the oral cavity impacted their treatment and s...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462419838102
更新日期：2019-06-01 00:00:00
abstract：:The brain gumma is a rare manifestation of the tertiary stage of syphilis. A case of neurosyphilitic gumma was confirmed by the Treponema pallidum polymerase chain reaction in a 46-year-old HIV-positive homosexual man. The patient presented with a severe headache and was hospitalized. A computed tomography scan was pe...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2007.007287
更新日期：2008-08-01 00:00:00
abstract：:We present the case of a 58-year-old HIV-infected patient with adrenal insufficiency after local injection of triamcinolone, most likely due to drug-drug interaction with his ritonavir-boosted antiretroviral therapy (ART). This is the first case of adrenal insufficiency occurring without prior symptoms of Cushing's sy...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462418768689
更新日期：2018-11-01 00:00:00
abstract：:The primary aim of the current study was to test the effect of the presentation design of a test alert system on healthcare workers' (HCWs') decision-making regarding blood-borne virus (BBV) testing. The secondary aim was to determine HCWs' acceptance of the system. An online survey used a within-subjects research des...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462420906998
更新日期：2020-07-01 00:00:00
abstract：:In Ireland the incidence of sexually transmitted infections (STIs) is steadily increasing while the number of new HIV-diagnoses in men who have sex with men has more than doubled in the past decade. This study investigated the prevalence of STIs in asymptomatic HIV-infected men who have sex with men (MSM) attending a ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1177/0956462414521165
更新日期：2014-09-01 00:00:00
abstract：:Genitourinary (GU) medicine notifications for homosexually acquired Chlamydia trachomatis (CT) infections show a 414% increase from 1996 to 2002. However, little is known about the prevalence of CT in men who have sex with men (MSM) outside GU medicine settings. Behavioural studies show that MSM with diagnosed HIV inf...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462054944507
更新日期：2005-09-01 00:00:00
abstract：:The completeness of a 'first consultation' human immunodeficiency virus (HIV) clinical history before and after the introduction of an HIV proforma was audited by a retrospective case notes review. Twenty key variables considered essential to every history were assessed. There was a significant improvement in the docu...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2007.007174
更新日期：2008-02-01 00:00:00
abstract：:The transmission efficiency of HIV-1 through unsafe medical injections can be estimated from seroconversions among health care workers (HCWs) after percutaneous exposures and documented iatrogenic outbreaks. Data from a case-control study of seroconversion after percutaneous exposures among US and European HCWs shows ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/0956462021924820
更新日期：2002-03-01 00:00:00
abstract：:The prompt and effective treatment of pelvic inflammatory disease (PID) may reduce the risk of complications such as infertility, ectopic pregnancy and pelvic pain. We conducted a national audit to investigate the treatment of women diagnosed with PID and associated rates of partner notification in genitourinary (GU) ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/ijsa.2011.011183
更新日期：2012-01-01 00:00:00
abstract：:The distribution of prevalent HIV-1 strains are still complex in China. Men who have sex with men (MSM) play an important bridging role in spreading HIV. The aim of our study was to quantitatively evaluate the prevalence of HIV-1 subtypes among the MSM population in China from published studies. Relevant studies were ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,meta分析,评审
doi：10.1177/0956462414543841
更新日期：2015-04-01 00:00:00
abstract：:Public health authorities have long believed that the preponderance of AIDS cases in Africa are attributable to 'heterosexual transmission'; most people silently assume this rubric to indicate penile-vaginal intercourse only. Recent epidemiologic analyses suggest that the majority of HIV cases in sub-Saharan Africa ma...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章,评审
doi：10.1258/095646203322025704
更新日期：2003-07-01 00:00:00
abstract：AIMS:To identify any differences in follow-up rates or sexual contact attendance rates in men presenting with non-gonococcal urethritis (NGU) after treatment by single dose azithromycin rather than longer standard duration therapies and to identify patients' treatment preferences. METHODS:A prospective study was perfo...
journal_title：International journal of STD & AIDS
pub_type： 临床试验,杂志文章
doi：10.1258/0956462961917591
更新日期：1996-05-01 00:00:00
abstract：:Using data from TREAT Asia HIV Observational Database (TAHOD), this paper aims to assess the rate of, and factors associated with the diagnosis of new AIDS-defining illness (ADI) within 90 days after antiretroviral treatment. Patients starting three or more antiretroviral combinations and having subsequent follow-up w...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646207781147283
更新日期：2007-07-01 00:00:00
abstract：:The 'dynias' are a group of chronic focal pain syndromes with a predilection for orocervical or urogenital regions. Only exceptionally do they involve both sites in the same patient. Here, we report a case of simultaneous occurrence of dysaesthetic peno/scroto dynia and stomatodynia. ...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646205774988154
更新日期：2005-12-01 00:00:00
abstract：:Sexually transmitted diseases (STDs) continue to be the most common notifiable infectious conditions worldwide. Their unacceptably high incidence is underlined by the recent emergence of a (presently) incurable and lethal STD--human immunodeficiency virus (HIV) infection--which merits its description as a pandemic, an...
journal_title：International journal of STD & AIDS
pub_type： 社论,评审
doi：10.1258/0956462961918419
更新日期：1996-11-01 00:00:00
abstract：:Five hundred and twenty consecutive women newly attending a genitourinary medicine clinic who participated in a study of sexual behaviour were also tested for type-specific antibody to herpes simplex virus type 2; 135 (26%) were seropositive, of whom only 29 (21.5%) had had clinical evidence of genital herpes. Seropos...
journal_title：International journal of STD & AIDS
pub_type： 杂志文章
doi：10.1258/095646203321043237
更新日期：2003-01-01 00:00:00
