Adrenal insufficiency due to ritonavir-triamcinolone drug-drug interaction without preceding Cushing's syndrome.

Abstract:

:We present the case of a 58-year-old HIV-infected patient with adrenal insufficiency after local injection of triamcinolone, most likely due to drug-drug interaction with his ritonavir-boosted antiretroviral therapy (ART). This is the first case of adrenal insufficiency occurring without prior symptoms of Cushing's syndrome in a patient on a booster-containing ART. We want to draw attention to this seemingly rare, but potentially life-threatening medical condition that can occur even in short-term use of glucocorticoids in low doses in patients on booster-containing ART and summarize some considerations for management.

journal_name

Int J STD AIDS

authors

Noe S,Jaeger H,Heldwein S

doi

10.1177/0956462418768689

subject

Has Abstract

pub_date

2018-11-01 00:00:00

pages

1136-1139

issue

11

eissn

0956-4624

issn

1758-1052

journal_volume

29

pub_type

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