Acculturation is associated with the prevalence of tardive dyskinesia and akathisia in community-treated patients with schizophrenia.

Abstract:

OBJECTIVE:Ethnicity is a risk factor for tardive dyskinesia (TD) and other antipsychotic drug-induced movement disorders (ADIMD). It is unclear whether this association is mediated through genetic, environmental or cultural factors individually or in combination. This pilot study aimed to explore this interaction by determining if acculturation in migrant groups contributed to the prevalence of ADIMD. METHOD:Culturally diverse but relatively genetically homogeneous (white Caucasian) patients with schizophrenia (n = 40) treated at a single site were assessed for the presence of ADIMD and level of acculturation. RESULTS:Higher levels of acculturation correlated with an increased prevalence of TD and akathisia but not Parkinsonism. The level of acculturation significantly predicted TD. CONCLUSION:This study identifies for the first time that acculturation significantly contributes to the prevalence of TD and akathisia but not Parkinsonism in culturally diverse migrant populations and must be accounted for when explaining ethnic variation in rates of ADIMD.

journal_name

Acta Psychiatr Scand

authors

Sundram S,Lambert T,Piskulic D

doi

10.1111/j.1600-0447.2008.01183.x

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

474-8

issue

6

eissn

0001-690X

issn

1600-0447

pii

ACP1183

journal_volume

117

pub_type

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