A rare case of leishmaniasis recidiva cutis evolving for 31 years caused by Leishmania tropica.

Abstract:

:A 64-year-old woman presented with erythematous, infiltrative plaques with a central atrophic area on both zygomatic regions. Several yellow-reddish papules were seen at the periphery of the plaques and showed an "apple-jelly" color on diascopy (Fig. 1). No visceral involvement was detected. The past medical history revealed that, at 3 years of age, she had developed an "Oriental sore" on both cheeks that healed with permanent scars. Thirty years later, she noticed an erythematous patch around the scars. She reported a hospital admission 22 years earlier for cutaneous leishmaniasis (CL); this was treated with pentavalent antimonial therapy for 10 days with partial improvement, when she refused further treatment. The lesions worsened in the summer and gradually became disfiguring, which prompted her to seek medical consultation. Laboratory findings were normal. Leishmania antibody titers were negative. Tissue samples were obtained by biopsy from the border of the lesion for culture, polymerase chain reaction (PCR), and histopathologic examination. Histology revealed a dermal infiltrate with tuberculoid granulomas surrounded by lymphocytes, histiocytes, and some plasma cells, but no caseation necrosis. A few Leishmania organisms were found on careful searching (Fig. 2). Leishmania tropica was identified by culture and PCR. A diagnosis of leishmaniasis recidiva cutis (LRC) was made on the basis of the anamnestic data together with the clinical, histopathologic, biologic, and molecular findings. Complete regression was achieved with meglumine antimoniate (Glucantime) given intramuscularly (15 mg Sb(V)/kg/day for 15 days) and cryosurgery with liquid nitrogen. No recurrence was noted during a 12-month follow-up period.

journal_name

Int J Dermatol

authors

Stefanidou MP,Antoniou M,Koutsopoulos AV,Neofytou YT,Krasagakis K,Krüger-Krasagakis S,Tselentis Y,Tosca AD

doi

10.1111/j.1365-4632.2008.03240.x

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

588-9

issue

6

eissn

0011-9059

issn

1365-4632

pii

IJD3240

journal_volume

47

pub_type

杂志文章
  • Characterization of circulating lymphocytes by monoclonal antibodies in childhood and adult leprosy.

    abstract::Peripheral blood lymphocyte assays using monoclonal antibodies were done in 66 patients with leprosy, consisting of 25 children and 41 adults. The results were statistically analyzed for correlations, if any, among the different age groups and matched controls. The results, however, failed to show any significant corr...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1991.tb04786.x

    authors: Sehgal VN,Chaudhry A,Sharma VK,Gupta CK

    更新日期:1991-11-01 00:00:00

  • Mongolian spots with involvement of the temporal area.

    abstract::A Chinese baby girl was born after an uncomplicated pregnancy and a normal spontaneous vaginal delivery to a gravida 2, para 1, 32-year-old mother at 37 weeks' gestation. Neither parent had a history of alcohol or drug ingestion. There was no history of consanguinity. The Apgar scores were 7 at 1 min and 9 at 5 min. H...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1046/j.1365-4362.2001.01212-4.x

    authors: Leung AK,Kao CP,Lee TK

    更新日期:2001-04-01 00:00:00

  • Pellagra probably due to pyrazinamide: development during combined chemotherapy of tuberculosis.

    abstract::Pellagra secondary to antituberculous chemotherapy can result from isoniazide therapy, as well as from pyrazinamide treatment. Because of the similarity in structural formulas between pyrazinamide, isoniazide, and nicotinamide, the substrate competition is the mechanism most likely involved. The patient was cured by a...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1983.tb02114.x

    authors: Jørgensen J

    更新日期:1983-01-01 00:00:00

  • Epidemiological and clinical patterns of genital lesions.

    abstract::A 5-year study of 668 patients with genital lesions revealed that teenagers and those in the age group of 20 to 40 are most vunerable. The poor, the uneducated and unmarried persons are at high risk. Chancroid and syphilis are the majority of cases. Inguinal bubo, herpes pregenitalis, condylomata acuminata, erosive ba...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:

    authors: Sehgal VN,Rege VL,Sehgal N,Kharangate VN,Mascarenhas MF

    更新日期:1976-10-01 00:00:00

  • Fibrin deposits and fibrinolytic activity in Schonlein-Henoch syndrome.

    abstract::Previous reports have shown that alterations in cutaneous and plasmatic fibrinolytic activity are found in cutaneous necrotizing vasculitis (CNV). In a combined investigation with direct immunofluorescence and autohistographic evaluation of tissue fibrinolytic activity in the lesional skin of 20 subjects affected by S...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1983.tb03323.x

    authors: Bianchini G,Lotti T,Fabbri P

    更新日期:1983-03-01 00:00:00

  • The outcome of using different surgical modalities and laser therapy in the treatment of small- and medium-sized congenital melanocytic nevi: a systematic review.

    abstract:OBJECTIVES:The purpose of this study is to review the published articles regarding different surgical modalities including laser therapy in the treatment of congenital melanocytic nevi (CMN). METHODS:A systematic review was done using several databases including PubMed, Ovid Medline, Google Scholar, and Medline to sea...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.14727

    authors: ALMutairi HM,Al-Hothali GI

    更新日期:2020-05-01 00:00:00

  • Epidermal changes associated with symptomatic resolution of dandruff: biomarkers of scalp health.

    abstract:BACKGROUND:Dandruff is a common scalp condition characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect underlying histopathologic and biochemical events that must be reversed if treatment is to be effective. OBJECTIVES:This study aimed to better characterize the state of the epidermis in...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1365-4632.2010.04629.x

    authors: Kerr K,Darcy T,Henry J,Mizoguchi H,Schwartz JR,Morrall S,Filloon T,Wimalasena R,Fadayel G,Mills KJ

    更新日期:2011-01-01 00:00:00

  • Longitudinal progress of transepidermal water loss, color, and sensory elements in split-thickness skin graft donor sites in East Asians.

    abstract:BACKGROUND:There is little research available that describes the natural progression of split-thickness skin graft (STSG) donor site wounds after re-epithelialization. The purpose of this study was to evaluate the longitudinal clinical progress of transepidermal water loss (TEWL), color, and sensory elements in STSG do...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.14389

    authors: Kim J,Kim R,Jeong W,Choi J,Park SW

    更新日期:2019-05-01 00:00:00

  • Nine cases of Japan spotted fever diagnosed at our hospital in 2008.

    abstract:BACKGROUND:The diagnosis of Japan spotted fever (JSF) is very difficult in some cases. The initial diagnosis of JSF is very important to treat. METHODS:We report nine cases of Japan spotted fever (JSF) with variable clinical features diagnosed at our hospital in 2008. RESULTS:Concerning clinical symptom, the most fre...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2010.04359.x

    authors: Kondo M,Nishii M,Gabazza EC,Kurokawa I,Akachi S

    更新日期:2010-04-01 00:00:00

  • Erythema nodosum leprosum in Nigeria.

    abstract::The occurrence of erythema nodosum leprosum among leprosy patients treated with diamino diphenyl sulfone in an endemic area is not rare, unlike in the leprosy patients treated at Lagos University Teaching Hospital. Two Nigerian patients with this disease are described, in whom this rarity was seen. Recurrent monthly f...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1975.tb00160.x

    authors: Somorin AO

    更新日期:1975-11-01 00:00:00

  • Clinical characteristics of patients with facial psoriasis in Malaysia.

    abstract:BACKGROUND:Psoriasis involving the face is visible and can cause considerable emotional distress to patients. Its presence may also confer a poorer prognosis for the patient. This study sought to evaluate the characteristics of facial psoriasis in Malaysia. METHODS:A cross-sectional study conducted using data from the...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.13307

    authors: Syed Nong Chek SR,Robinson S,Mohd Affandi A,Baharum N

    更新日期:2016-10-01 00:00:00

  • Etanercept therapy allows the tapering of methotrexate and sustained clinical responses in patients with moderate to severe psoriasis.

    abstract::Methotrexate, the most common systemic small molecule used in the treatment of moderate to severe psoriasis, is associated with significant toxicities and adverse events. Long-term continuous usage is not recommended due to potential liver toxicity, myelosuppression, and other side effects. Abrupt cessation of methotr...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2008.03419.x

    authors: Yamauchi PS,Lowe NJ

    更新日期:2008-02-01 00:00:00

  • Basal cell carcinoma in tropical Australia.

    abstract::A survey of people with skin cancer in tropical Australia detected a change in site of the prevalent cancer. In the post-war generation more basal cell carcinomas are occurring on the back and fewer on the head and neck. A reversal of the sex ratio was also detected, with more women being afflicted. ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1992.tb02667.x

    authors: Czarnecki D,Collins N,Nash C

    更新日期:1992-06-01 00:00:00

  • Ossification of the auricle.

    abstract::The auricle is a flexible structure because it is formed by elastic cartilage. In the rare occurrence of ectopic auricular ossification, however, the cartilage is replaced by lamellar bone and becomes petrified. Such unphysiological replacement has been reported in association with local trauma, inflammation, systemic...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2007.03512.x

    authors: Sterneberg-Vos H,Winnepenninckx V,Frank J,Kelleners-Smeets NW

    更新日期:2007-11-01 00:00:00

  • Serum mucosa-associated epithelial chemokine (MEC/CCL28) in atopic dermatitis: a specific marker for severity.

    abstract:BACKGROUND:Mucosa-associated epithelial chemokine (MEC; CCL28) is considered to be pivotal in mediating the migration of CC chemokine receptor 3- and 10- (CCR3- and CCR10)-expressing, skin-homing, memory, cutaneous lymphocyte-associated antigen-positive (CLA(+)) T cells. CCL28 is selectively and continuously expressed ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2009.04069.x

    authors: Ezzat MH,Sallam MA,Shaheen KY

    更新日期:2009-08-01 00:00:00

  • Acupuncture in dermatology: an historical perspective.

    abstract::Classical acupuncture focuses primarily on treating the person, and secondarily treating the illness. The "symptoms" are regarded as "branch" expressions of a "root" (constitutional) imbalance. Different root imbalances can produce the same symptoms. Five patients with eczema, for example, may reveal five distinct roo...

    journal_title:International journal of dermatology

    pub_type: 历史文章,杂志文章

    doi:10.1111/j.1365-4632.2009.03899.x

    authors: Tan EK,Millington GW,Levell NJ

    更新日期:2009-06-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus in community-acquired pyoderma.

    abstract:BACKGROUND:Methicillin-resistant Staphylococcus aureus (MRSA) is an important nosocomial pathogen. It can also cause community-acquired infections. Indian reports about MRSA in community-acquired infections are rare. AIM:To evaluate the rate of MRSA in community-acquired pyoderma and the nasal colonisation with S. aur...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2004.02138.x

    authors: Nagaraju U,Bhat G,Kuruvila M,Pai GS,Jayalakshmi,Babu RP

    更新日期:2004-06-01 00:00:00

  • Keratosis lichenoides chronica in an Indian child following erythroderma.

    abstract::A 4-year-old boy presented with mildly itchy, linear, skin lesions over the trunk, arms, and face of 3 months' duration. He had previously been admitted to a private hospital for generalized exfoliation of the skin following drug intake for fever and throat pain. The nature of the drugs was not known. The exfoliative ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2008.03618.x

    authors: Ghorpade A

    更新日期:2008-09-01 00:00:00

  • Erosive pustular dermatosis of the scalp: causes and treatments.

    abstract::Erosive pustular dermatosis of the scalp is a rare condition which primarily affects older women after local trauma and has historically been treated with topical steroids. As it is a rare entity and resembles other dermatologic conditions, it may easily be misdiagnosed. Identifying the causes and evaluating the effic...

    journal_title:International journal of dermatology

    pub_type: 杂志文章,评审

    doi:10.1111/ijd.14955

    authors: Karanfilian KM,Wassef C

    更新日期:2021-01-01 00:00:00

  • Surgical pearl: a simple means of disarming the "locked and loaded" needle.

    abstract:BACKGROUND:Surgery, in any setting, has several inherent risks not only to the patient, but the physician and his assistants as well. Safe handling and management of the sharps to prevent inoculation injuries is one of these risks, in particular: 1) instrument hand-off of the needle and needle driver between the physic...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2008.03651.x

    authors: Kunishige J,Wanitphakdeedecha R,Nguyen TH,Chen TM

    更新日期:2008-08-01 00:00:00

  • Cardiovascular risk factors in subjects with psoriasis: a cross-sectional general population study.

    abstract:BACKGROUND:Epidemiological data have established an association between cardiovascular disease and psoriasis. Only one general population study has so far compared prevalences of cardiovascular risk factors among subjects with psoriasis and control subjects. We aimed to determine the prevalence of cardiovascular risk f...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4632.2011.05408.x

    authors: Jensen P,Thyssen JP,Zachariae C,Hansen PR,Linneberg A,Skov L

    更新日期:2013-06-01 00:00:00

  • Successful treatment of a patient with recurrent furunculosis by vitamin C: improvement of clinical course and of impaired neutrophil functions.

    abstract:BACKGROUND:Neutrophils play a critical role in host defense against a variety of microbial pathogens. There is much information to suggest a role for vitamin C in the physiology of neutrophils. Thus, the effects of vitamin C treatment were studied in a patient with a history of recurrent furunculosis who showed altered...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1993.tb02780.x

    authors: Levy R,Schlaeffer F

    更新日期:1993-11-01 00:00:00

  • Long-term follow-up and management of small and medium-sized CD4+ T cell lymphoma and CD8+ lymphoid proliferations of acral sites: a multicenter experience.

    abstract:BACKGROUND:Primary cutaneous CD4+ small-medium pleomorphic T cell lymphoma (SMPTCL) is a low-grade cutaneous T cell lymphoma. Its clinical and histopathologic features are comparable with those of CD8+ lymphoid proliferations (LPs) of the ear and acral sites. OBJECTIVES:We performed a retrospective analysis of patient...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.13340

    authors: Virmani P,Jawed S,Myskowski PL,Horwitz S,Skripnik Lucas A,Moskowitz A,Pulitzer M,Zain J,Rosen ST,Querfeld C

    更新日期:2016-11-01 00:00:00

  • The combination of overweight and smoking increases the severity of androgenetic alopecia.

    abstract:INTRODUCTION:Even though androgenetic alopecia (AGA) is the most common type of alopecia, factors associated with AGA severity have been poorly investigated. OBJECTIVES:The objective of our study was to investigate risk factors for AGA severity among a Caucasian population. METHODS:A cross-sectional study was conduct...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.13652

    authors: Fortes C,Mastroeni S,Mannooranparampil TJ,Ribuffo M

    更新日期:2017-08-01 00:00:00

  • Allergic reactions to insulin.

    abstract::Allergic reactions to insulin, although very common, are usually mild and self-limited. Many persistent effects can be corrected by simple means available to the discerning physician. In a few patients, however, they are severe and cause extreme morbidity or even mortality. These patients need to be recognized promptl...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1980.tb00277.x

    authors: Jegasothy BV

    更新日期:1980-04-01 00:00:00

  • IgA dermatosis in an adult Chinese population. A 10-year study of linear IgA and dermatitis herpetiformis in Singapore.

    abstract::During a 10-year period (1976-1985), eight Chinese patients from a population of 2.5 million fulfilled the criteria for dermatitis herpetiformis and linear IgA bullous dermatosis (LABD). These rare diseases among Asians presented during the third decade of life with homogenous linear IgA deposits along the dermoepider...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1988.tb02328.x

    authors: Ratnam KV

    更新日期:1988-01-01 00:00:00

  • Hypocomplementemic urticarial vasculitis arising in a patient with immunoglobulin G4-related disease.

    abstract:BACKGROUND:Hypocomplementemic urticarial vasculitis (HUV) has been defined as a syndrome associated with urticarial lesions caused by leukocytoclastic vasculitis. It has been observed in patients with systemic lupus erythematosus and related conditions. Immunoglobulin G4 (IgG4)-related disease is a lymphoproliferative ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.12868

    authors: Takao M,Hamada T,Kaji T,Ikeda-Mizuno K,Takehara-Yasuhara C,Ichimura K,Yanai H,Yshino T,Iwatsuki K

    更新日期:2016-04-01 00:00:00

  • Premycotic poikiloderma, mycosis fungoides and cutaneous squamous cell carcinoma. Two cases and a discussion of their relevance.

    abstract::Two patients with premycotic poikiloderma developed one squamous cell carcinoma each. A review of the literature reveals 28 reported cases of this association, but in 26 of these the patient had been exposed to carcinogens. Our patients had no history of exposure to carcinogenic agents. In both our cases, the squamous...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1986.tb03424.x

    authors: Colver G,Mortimer P,Dawber R

    更新日期:1986-07-01 00:00:00

  • The course and prognosis of pemphigus. A review of 115 patients.

    abstract::A survey of 115 pemphigus patients who have been followed for 4-24 years was carried out in an attempt to analyze the possible factors influencing the course and prognosis of the disease. At the time of the study, 45 patients were in complete remission, 45 still had lesions, and 25 had died. In 12 cases, the death occ...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/j.1365-4362.1988.tb02409.x

    authors: Seidenbaum M,David M,Sandbank M

    更新日期:1988-10-01 00:00:00

  • Topical mechlorethamine for psoriasis. An attempt to avoid the development of sensitization by the use of a topical tolerogenic schedule.

    abstract::The topical application of mechlorethamine is associated with a high incidence of irritant contact dermatitis. An attempt was made to avoid this complication by the use of a topical tolerogenic schedule. Seven of ten patients developed contact dermatitis to the medication after they had completed the schedule, The use...

    journal_title:International journal of dermatology

    pub_type: 杂志文章

    doi:10.1111/ijd.1979.18.5.390

    authors: Price NM

    更新日期:1979-06-01 00:00:00