Abstract:
PURPOSE/OBJECTIVES:To determine the effect of aerobic and strength resistance training and epoetin alfa (EPO) therapy on transfusions, stem cell collections, transplantation recovery, and multiple myeloma treatment response. DESIGN:Randomized clinical trial. SETTING:A myeloma research and therapy center in the south central United States. SAMPLE:135 patients with multiple myeloma, 120 evaluable. METHODS:Random assignment to exercise or usual care groups. All patients received EPO based on an algorithm. Aerobic capacity, using the six-minute walk test, was assessed prior to induction chemotherapy, prior to stem cell mobilization, and following stem cell collection for all patients and before and after transplantation for patients continuing in the study. Data analysis included analysis of variance to compare other outcome variables by groups. MAIN RESEARCH VARIABLES:Number of red blood cell and platelet transfusions during transplantation, number of attempts at and total number of days of stem cell collection, time to recovery after transplantation, and response to intensive therapy for multiple myeloma. FINDINGS:Recovery and treatment response were not significantly different between groups after transplantation. The exercise group had significantly fewer red blood cell transfusions and fewer attempts at stem cell collection. Serious adverse events were similar in each group. CONCLUSIONS:Exercise with prophylactic EPO therapy reduces the number of RBC transfusions and attempts at stem cell collection for patients receiving intensive treatment for multiple myeloma. IMPLICATIONS FOR NURSING:Exercise is safe and has many physiologic benefits for patients receiving multiple myeloma treatment.
journal_name
Oncol Nurs Forumjournal_title
Oncology nursing forumauthors
Coleman EA,Coon SK,Kennedy RL,Lockhart KD,Stewart CB,Anaissie EJ,Barlogie Bdoi
10.1188/08.ONF.E53-E61subject
Has Abstractpub_date
2008-05-01 00:00:00pages
E53-61issue
3eissn
0190-535Xissn
1538-0688pii
9708G6K47W6452R4journal_volume
35pub_type
杂志文章,随机对照试验abstract:PURPOSE/OBJECTIVES:To assess feasibility of using electronic health records for profiling multiple cardiovascular disease (CVD) risk factors in women with breast cancer at diagnosis and five years post-treatment, and to explore relationships among CVD risk factors and breast cancer outcomes . DESIGN:Retrospective, des...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/15.ONF.E330-E338
更新日期:2015-09-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To identify symptom clusters in older adult breast cancer survivors (ages 65-97 years) and examine whether symptom clusters are related to demographic, health, and quality-of-life variables. DESIGN:Factor analysis to identify possible symptom clusters. The resulting clusters then were correlated wit...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/11.ONF.672-680
更新日期:2011-11-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To review normal calcium homeostasis, recent advances in understanding the pathologic mechanisms responsible for precipitating hypercalcemia of malignancy, the role of the kidneys in potentiating hypercalcemia, and the principles of antihypercalcemic treatment. DATA SOURCES:Journal articles, edited ...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:
更新日期:1994-07-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To synthesize the literature regarding research on hope in adults with cancer. DATA SOURCES:CINAHL Plus® and PsycINFO databases. DATA SYNTHESIS:Sixteen articles published from 2005-2009 met the criteria for review. The literature was organized according to Oncology Nursing Society levels of evidenc...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:10.1188/11.ONF.E341-E350
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abstract:PURPOSE/OBJECTIVES:To advance the goals of evidence-based care and prioritize the knowledge generation that addresses contemporary challenges in oncology nursing. Results are used to inform the development of the Oncology Nursing Society (ONS) Research Agenda and by the ONS Foundation to develop strategic research init...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/14.ONF.67-76
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abstract:PURPOSE/OBJECTIVES:To describe the side-effects burden experienced over time by 53 women who were receiving treatment for breast cancer and to describe the association of side-effects burden with psychological adjustment and life quality. DESIGN:Data were drawn from the Self-Help Intervention Project (SHIP), an interv...
journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-06-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To review the drug profiles and nursing implications of Camptosar (irinotecan) (pharmacia & Upjohn, Inc., Kalamazoo, MI), Hycamtin (topotecan) (SmithKline Beecham Oncology,Philadelphia, PA), 9-aminocamptothecin TM (9-AC) (Pharmacia & Upjohn, Inc.), Taxotere (docetaxel) (Rhône-Poulenc Rorer Pharmaceut...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:
更新日期:1997-01-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To examine the currently available antiemetic medications and review their uses in the treatment of chemotherapy-induced nausea and vomiting (NV). DATA SOURCES:Published articles and book chapters. DATA SYNTHESIS:NV is a common yet potentially serious side effect of chemotherapy. Nurses must unders...
journal_title:Oncology nursing forum
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1995-07-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To determine information about Filipino American women's perceptions of breast cancer, the most frequently diagnosed cancer and number-one killer of Asian American women, and their experiences with screening. DESIGN:A qualitative, exploratory approach with focus groups. SETTING:Suburban Filipino Am...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/06.ONF.E71-E78
更新日期:2006-07-01 00:00:00
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journal_title:Oncology nursing forum
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/13.ONF.464-471
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/10.ONF.61-68
更新日期:2010-01-01 00:00:00
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journal_title:Oncology nursing forum
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journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract::Recently, clinicians and researchers alike have challenged the long-standing impression that survivors of bone marrow transplantation (BMT) experience a less than optimal quality of life (QOL). Despite the accumulating evidence suggesting that most adult survivors adjust relatively well within two to five years after ...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:1993-11-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章,随机对照试验
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abstract:PURPOSE/OBJECTIVES:To describe the usefulness of daily pain management diaries to outpatients with cancer who participated in a randomized clinical trial of the PRO-SELF Pain Control Program. DESIGN:Randomized clinical trial in which a daily pain management diary was used for data collection in the control group and f...
journal_title:Oncology nursing forum
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2002-10-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To describe social support from the perspective of Japanese women with breast cancer. DESIGN:Qualitative, descriptive, and interpretive. SETTING:Outpatient breast clinic at a cancer center in a metropolitan area in Japan. SAMPLE:Sixteen Japanese women diagnosed with stage I and II breast cancer wh...
journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:2000-10-01 00:00:00
abstract::The primary goal of the thousands of registered trials in cancer research is to extend survival. With evaluation of efficacy, safety, and tolerability, healthcare providers must ensure that the principles described in the Belmont Report are upheld and that patients are truly informed when signing a consent form. In th...
journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/07.ONF.713-720
更新日期:2007-05-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2019-07-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:PURPOSE/OBJECTIVES:To explore patients' quality of life (QOL) as defined by RNs in adult and pediatric oncology settings and to examine, from the perspectives of clinical nurses, the knowledge that is needed to apply QOL research outcomes in clinical practice. DESIGN:Qualitative research design using a focus group tec...
journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2002-11-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2016-03-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
doi:10.1188/08/ONF.661-669
更新日期:2008-07-01 00:00:00
abstract::High-dose cytosine arabinoside (HDAC) is used to treat adults with acute and chronic leukemia and non-Hodgkin's lymphoma. Although HDAC is associated with various toxicities, cutaneous toxicity in particular leads to alterations in comfort, interference with daily living activities, and increased risk of infection. Th...
journal_title:Oncology nursing forum
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
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journal_title:Oncology nursing forum
pub_type: 杂志文章
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更新日期:2016-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00