Abstract:
:The accuracy of in vivo dopamine D2 receptor quantification by positron emission tomography (PET) was determined for several models by means of singular-value decomposition, and some of the model assumptions were reviewed. These include steady-state, transient, double injection, and equilibrium approaches. All four modes are augmented by including a realistic kinetic interaction of the radioligand with the striatal serotonin S2 receptor. When a set of parameters derived specifically with reference to the equilibrium model was applied, it was found that a reversible radioligand used in conjunction with the equilibrium model permits accurate quantification. However, an assumption of the equilibrium model-that equilibrium is achieved during the time of measurement-is shown to be unsupported by the published experimental data. These results indicate that the equilibrium approach can provide an alternative to the kinetic approaches, but that additional experimental evidence is required to demonstrate the validity of the equilibrium assumption.
journal_name
IEEE Trans Med Imagingjournal_title
IEEE transactions on medical imagingauthors
Zeeberg BR,Gibson RE,Reba RCdoi
10.1109/42.7783subject
Has Abstractpub_date
1988-01-01 00:00:00pages
203-12issue
3eissn
0278-0062issn
1558-254Xjournal_volume
7pub_type
杂志文章abstract::The National Library of Medicine (NLM) is developing a digital chest X-ray (CXR) screening system for deployment in resource constrained communities and developing countries worldwide with a focus on early detection of tuberculosis. A critical component in the computer-aided diagnosis of digital CXRs is the automatic ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2013.2290491
更新日期:2014-02-01 00:00:00
abstract::The reconstruction of MR quantitative susceptibility mapping (QSM) from local phase measurements is an ill posed inverse problem and different regularization strategies incorporating a priori information extracted from magnitude and phase images have been proposed. However, the anatomy observed in magnitude and phase ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2544958
更新日期:2016-09-01 00:00:00
abstract::Magnetic resonance imaging (MRI) has been commonly used for guiding and planning image guided interventions since it provides excellent soft tissue visualization of anatomy and allows motion modeling to predict the position of target tissues during the procedure. However, MRI-based motion modeling remains challenging ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2011.2181997
更新日期:2012-03-01 00:00:00
abstract::Free-breathing cardiac diffusion tensor imaging (DTI) is a promising but challenging technique for the study of fiber structures of the human heart in vivo. This work proposes a clinically compatible and robust technique to provide three-dimensional (3-D) fiber architecture properties of the human heart. To this end, ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2014.2356792
更新日期:2015-01-01 00:00:00
abstract::This paper investigates the problem of atlas registration of brain images with gliomas. Multiparametric imaging modalities (T1, T1-CE, T2, and FLAIR) are first utilized for segmentations of different tissues, and to compute the posterior probability map (PBM) of membership to each tissue class, using supervised learni...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2010.2078833
更新日期:2011-02-01 00:00:00
abstract::Ultrafast ultrasound imaging using plane or diverging waves, instead of focused beams, has advanced greatly the development of novel ultrasound imaging methods for evaluating tissue functions beyond anatomical information. However, the sonographic signal-to-noise ratio (SNR) of ultrafast imaging remains limited due to...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2781261
更新日期:2018-04-01 00:00:00
abstract::The purpose of this study is to develop and test a new computerized model for predicting near-term breast cancer risk based on quantitative assessment of bilateral mammographic image feature variations in a series of negative full-field digital mammography (FFDM) images. The retrospective dataset included series of fo...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2016.2527619
更新日期:2016-07-01 00:00:00
abstract::Microwave radar imaging is promising as a complementary medical imaging modality. However, the unique nature of the images means interpretation can be difficult. As a result, it is important to understand the sources of image differences, and how much variability is inherent in the imaging system itself. To address th...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2018.2806878
更新日期:2018-08-01 00:00:00
abstract::A method is described which enables unambiguous retrieval of sign information in a set of magnetic resonance magnitude images of the inversion recovery type. The proposed method starts from the observation that the inversion recovery curve S is a monotonically increasing function of the inversion time TI, and comes do...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.1984.4307681
更新日期:1984-01-01 00:00:00
abstract::Colorectal cancer can easily be prevented provided that the precursors to tumors, small colonic polyps, are detected and removed. Currently, the only definitive examination of the colon is fiber-optic colonoscopy, which is invasive and expensive. Computed tomographic colonography (CTC) is potentially a less costly and...
journal_title:IEEE transactions on medical imaging
pub_type: 临床试验,杂志文章
doi:10.1109/TMI.2002.806405
更新日期:2002-12-01 00:00:00
abstract::Anisotropic multi-slice Cardiac Magnetic Resonance (CMR) Images are conventionally acquired in patient-specific short-axis (SAX) orientation. In specific cardiovascular diseases that affect right ventricular (RV) morphology, acquisitions in standard axial (AX) orientation are preferred by some investigators, due to po...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2021.3052972
更新日期:2021-01-20 00:00:00
abstract::The interest of compressive sampling in ultrasound imaging has been recently extensively evaluated by several research teams. Following the different application setups, it has been shown that the RF data may be reconstructed from a small number of measurements and/or using a reduced number of ultrasound pulse emissio...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2015.2493241
更新日期:2016-03-01 00:00:00
abstract::Kidney stone disease is a major health problem worldwide. Shockwave lithotripsy (SWL), which uses high-energy shockwave pulses to break up kidney stones, is extensively used in clinic. However, despite its noninvasiveness, SWL can produce cavitation in vivo. The rapid expansion and violent collapse of cavitation bubbl...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2928740
更新日期:2020-02-01 00:00:00
abstract::In radiology, as a result of the increased utilization of digital imaging modalities, such as computed tomography (CT) and magnetic resonance imaging (MRI), over a third of the images produced in a typical radiology department are currently in digital form, and this percentage is steadily increasing. Image compression...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.1986.4307750
更新日期:1986-01-01 00:00:00
abstract::This paper describes a multimodality framework for computer-aided myocardial viability assessment based on neuro-fuzzy techniques. The proposed approach distinguishes two main levels: the modality-independent inference level and the modality-dependent application level. This two-level distinction releases the hard con...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.974925
更新日期:2001-12-01 00:00:00
abstract::A two-stage adaptive vector quantization scheme for radiographic image sequence coding is introduced. Each frame in the sequence is first decomposed into a set of vectors, corresponding to nonoverlapping spatially contiguous block of pixels. A codebook is generated using a training set of vectors drawn from the sequen...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.3938
更新日期:1988-01-01 00:00:00
abstract::We describe a fast forward and back projector pair based on inverse Fourier rebinning for use in iterative image reconstruction for fully three-dimensional (3-D) positron emission tomography (PET). The projector pair is used as part of a factored system matrix that takes into account detector-pair response by using sh...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:
更新日期:2007-03-01 00:00:00
abstract::Lung cancer is the leading cause of cancer deaths worldwide and early diagnosis of lung nodule is of great importance for therapeutic treatment and saving lives. Automated lung nodule analysis requires both accurate lung nodule benign-malignant classification and attribute score regression. However, this is quite chal...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2019.2934577
更新日期:2020-03-01 00:00:00
abstract::Myocardial tissue characterization using ultrasound is a growing area of investigation which attempts to evaluate the structure of the myocardium by analysis of ultrasound signals. Our laboratory has been exploring the use of texture analysis for the determination of myocardial tissue properties from two-dimensional e...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.1985.4307721
更新日期:1985-01-01 00:00:00
abstract::Multisource cone-beam computed tomography (CT) is an attractive approach of choice for superior temporal resolution, which is critically important for cardiac imaging and contrast enhanced studies. In this paper, we present a filtered-backprojection (FBP) algorithm for triple-source helical cone-beam CT. The algorithm...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2008.2004817
更新日期:2009-03-01 00:00:00
abstract::We have developed a method to study the statistical properties of the noise found in various medical images. The method is specifically designed for types of noise with uncorrelated fluctuations. Such signal fluctuations generally originate in the physical processes of imaging rather than in the tissue textures. Vario...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2004.832656
更新日期:2004-10-01 00:00:00
abstract::A computationally efficient mixed feature based neural network (MFNN) is proposed for the detection of microcalcification clusters (MCCs) in digitized mammograms. The MFNN employs features computed in both the spatial and spectral domain and uses spectral entropy as a decision parameter. Backpropagation with Kalman fi...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.538936
更新日期:1996-01-01 00:00:00
abstract::Component averaging (CAV) was recently introduced by Censor, Gordon, and Gordon as a new iterative parallel technique suitable for large and sparse unstructured systems of linear equations. Based on earlier work of Byrne and Censor, it uses diagonal weighting matrices, with pixel-related weights determined by the spar...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.959302
更新日期:2001-10-01 00:00:00
abstract::Radio-frequency (RF) transceiver array design using primary and higher order harmonics for in vivo parallel magnetic resonance imaging imaging (MRI) and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities ...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2011.2166273
更新日期:2012-02-01 00:00:00
abstract::Thin, dense interslice septa have long been used to reduce the scattered radiation collected in positron emission tomography (PET). These septa prevent the acquisition of coincident gamma rays that are oblique to the scanning planes. Several volume imaging systems that acquire oblique rays have been built. The reasons...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.222675
更新日期:1993-01-01 00:00:00
abstract::If a flow field exists within an object that is being imaged, there could be a velocity spectrum in each voxel due to the finite voxel size. Consequently, the mean value and the variance of velocity in each voxel can be defined and used to describe the velocity spectrum. An NMR (nuclear magnetic resonance) imaging tec...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.14520
更新日期:1988-01-01 00:00:00
abstract::The theory and techniques of compressed sensing (CS) have shown their potential as a breakthrough in accelerating k-space data acquisition for parallel magnetic resonance imaging (pMRI). However, the performance of CS reconstruction models in pMRI has not been fully maximized, and CS recovery guarantees for pMRI are l...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2015.2474383
更新日期:2016-01-01 00:00:00
abstract::Ultrasound molecular imaging (USMI) is accomplished by detecting microbubble (MB) contrast agents that have bound to specific biomarkers, and can be used for a variety of imaging applications, such as the early detection of cancer. USMI has been widely utilized in preclinical imaging in mice; however, USMI in humans c...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2774814
更新日期:2018-01-01 00:00:00
abstract::We present a novel method to segment instances of glandular structures from colon histopathology images. We use a structure learning approach which represents local spatial configurations of class labels, capturing structural information normally ignored by sliding-window methods. This allows us to reveal different sp...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/TMI.2017.2750210
更新日期:2018-01-01 00:00:00
abstract::The Newton-Raphson (N-R) with two different regularization methods: the Levenberg-Marquardt (N-R-LM) and the Hachtel's Augmented Matrix (N-R-HAM), were used to reconstruct images of conductivity changes in a cylindrical medium by Induced Current Electrical Impedance Tomography (ic-EIT). Experimental data were obtained...
journal_title:IEEE transactions on medical imaging
pub_type: 杂志文章
doi:10.1109/42.491419
更新日期:1996-01-01 00:00:00