Is routine infectious and toxicologic screening in preterm labor effective in predicting preterm birth?

Abstract:

OBJECTIVE:Our objective was to evaluate whether a significant association exists between cocaine use, cervical, urine, and/or Group B streptococcus (GBS) infections and preterm birth (PTB) in patients admitted with active preterm labor (PTL). STUDY DESIGN:A retrospective cohort study of PTL patients < 34 weeks (n = 400) admitted to a large, urban tertiary care hospital (2002-2005) was performed. Pertinent history and screening test results were collected. The prevalence of a positive result for each test was determined. Pearson chi-square and Poisson regression were used to evaluate the significance of associations between screening tests and PTB and to control for confounders. RESULTS:The percentage of patients that delivered at < 37 and < 34 weeks was 63.5% (n = 254) and 44.5% (n = 178), respectively. Only cocaine use was significantly associated with PTB at < 34 weeks (RR 1.86, 95%CI 1.03, 2.08). CONCLUSION:This laboratory test panel is not an effective adjunctive means to predict PTB in PTL patients.

journal_name

Am J Obstet Gynecol

authors

Bastek JA,Sammel MD,Srinivas SK,Elovitz MA

doi

10.1016/j.ajog.2007.10.777

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

e38-42

issue

5

eissn

0002-9378

issn

1097-6868

pii

S0002-9378(07)01695-X

journal_volume

198

pub_type

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