HPLC enantioseparation and absolute configuration of novel anti-inflammatory pyrrole derivatives.

Abstract:

:The assignment of the absolute configuration of novel anti-inflammatory pyrrole derivatives has been accomplished by a combined strategy based on independent physical methods. The key step of our stereochemical characterization approach is the production at mg-scale of enantiomerically pure forms by HPLC on Chiralpak IA stationary phase.

journal_name

Chirality

journal_title

Chirality

authors

Biava M,Cirilli R,Fares V,Ferretti R,Gallinella B,La Torre F,Poce G,Porretta GC,Supino S,Villani C

doi

10.1002/chir.20518

subject

Has Abstract

pub_date

2008-06-01 00:00:00

pages

775-80

issue

6

eissn

0899-0042

issn

1520-636X

journal_volume

20

pub_type

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