Abstract:
:Strong selection within a given population locally reduces genetic variability not only in the selected gene itself but also in neighbouring loci. This so-called hitch-hiking effect is related to the initial linkage disequilibrium between markers and the selected gene, and depends mainly on the number of copies of the beneficial allele at the start of the selection phase. Contrary to the classical case, in which selection acts on a single, newly arisen beneficial mutation, we considered selection from standing variation (soft selective sweeps) on a gene (Rht-B1) with a major effect on plant height, a selected trait in an experimental wheat population grown for 17 generations, and we documented the evolution of gene diversity and linkage disequilibrium near this gene. As expected, Rht-B1 was found to be under strong selection (s = 0.15) and its variation in frequency accounted for 15% of the total trait evolution. This led to a smaller genetic effective population size at Rht-B1 (N(eg) = 18) compared to the whole genome estimation (N(eg) = 167). When compared with expectations under genetic drift only, no significant decrease in gene diversity was found at the closest loci. We computed expected di-locus frequencies for any linked marker-Rht-B1 pair due to hitch-hiking effects. We found that hitch-hiking was expected to affect the two most closely linked loci, but expected reduction in gene diversity was not greater than that due to genetic drift, which was consistent with the observations. Such limited effect was attributed to the low level of linkage disequilibrium (0.16) estimated after parental intercrosses, together with a relatively high initial frequency of the gene. This situation is favourable to candidate gene approaches where small linkage disequilibrium around selected genes is expected.
journal_name
Mol Ecoljournal_title
Molecular ecologyauthors
Raquin AL,Brabant P,Rhoné B,Balfourier F,Leroy P,Goldringer Idoi
10.1111/j.1365-294X.2007.03620.xsubject
Has Abstractpub_date
2008-02-01 00:00:00pages
741-56issue
3eissn
0962-1083issn
1365-294Xpii
MEC3620journal_volume
17pub_type
杂志文章abstract::Few studies have investigated the genetic structure of both host and parasite populations at a level of populations and at a level of individuals. We investigated the genetic structure of the urban cockroach Blattella germanica and its oxyuroid parasite Blatticola blattae. Random amplified polymorphic DNA (RAPD) marke...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2000.00880.x
更新日期:2000-04-01 00:00:00
abstract::Studying hybridization has the potential to elucidate challenging questions in evolutionary biology such as the nature of adaptive genetic variation and reproductive isolation. A growing body of work highlights that the merging of divergent genomes goes beyond the reshuffling of standing variation from related species...
journal_title:Molecular ecology
pub_type: 评论,新闻
doi:10.1111/mec.14247
更新日期:2017-09-01 00:00:00
abstract::Throughout the eukaryotes, sexual reproduction is an almost universal phenomenon. However, within the Kingdom Fungi, this relationship is not so clear-cut. Fungi exhibit a spectrum of reproductive modes and life-cycles; amongst the better known species, sexual reproduction is often facultative, can be rare, and in ove...
journal_title:Molecular ecology
pub_type: 评论,杂志文章
doi:10.1111/j.1365-294X.2012.05506.x
更新日期:2012-03-01 00:00:00
abstract::Discovering cryptic species in well-studied areas and taxonomic groups can have profound implications in understanding eco-evolutionary processes and in nature conservation because such groups often involve research models and act as flagship taxa for nature management. In this study, we use an array of techniques to ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13756
更新日期:2016-09-01 00:00:00
abstract::We studied population polymorphism at a major histocompatibility complex (MHC) class II beta gene in the deer mouse (Peromyscus maniculatus). We found that: (i) a single population of P. maniculatus has significantly higher levels of DNA and protein sequence diversity than worldwide samples from homologous genes in ot...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.0962-1083.2001.01402.x
更新日期:2001-12-01 00:00:00
abstract::Experimental evolution (EE) combined with whole-genome sequencing (WGS) has become a compelling approach to study the fundamental mechanisms and processes that drive evolution. Most EE-WGS studies published to date have used microbes, owing to their ease of propagation and manipulation in the laboratory and relatively...
journal_title:Molecular ecology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-294X.2012.05484.x
更新日期:2012-05-01 00:00:00
abstract::Investigating how environmental features shape the genetic structure of populations is crucial for understanding how they are potentially adapted to their habitats, as well as for sound management. In this study, we assessed the relative importance of spatial distribution, ocean currents and sea surface temperature (S...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13811
更新日期:2016-10-01 00:00:00
abstract::Hybridization among conspecifics in native and introduced habitats has important implications for biological invasions in new ecosystems. Bighead (Hypophthalmichthys nobilis) and silver carp (H. molitrix) are genetically isolated and occur in sympatry within their native range. Following their introduction to North Am...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13285
更新日期:2015-08-01 00:00:00
abstract::Wolbachia is a common heritable bacterial symbiont in insects. Its evolutionary success lies in the diverse phenotypic effects it has on its hosts coupled to its propensity to move between host species over evolutionary timescales. In a survey of natural host-symbiont associations in a range of Drosophila species, we ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.14164
更新日期:2017-08-01 00:00:00
abstract::Species may often exhibit geographic variation in population genetic structure due to contemporary and historical variation in population size and gene flow. Here, we test the predictions that populations on the margins of a species' distribution contain less genetic variation and are more differentiated than populati...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2007.03241.x
更新日期:2007-04-01 00:00:00
abstract::The process of discovering species is a fundamental responsibility of systematics. Recently, there has been a growing interest in coalescent-based methods of species delimitation aimed at objectively identifying species early in the divergence process. However, few empirical studies have compared these new methods wit...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.12446
更新日期:2013-10-01 00:00:00
abstract::We examined male reproductive success in a common brushtail possum population in New Zealand farmland. Paternity was assigned to 66 of 91 pouch young (maternity known), using a likelihood approach applied to genotypes at six microsatellite loci having an overall average exclusion probability of around 99%. The distrib...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2000.00941.x
更新日期:2000-07-01 00:00:00
abstract::We investigated the genetic outcome of successful invasion by an alien species, the marsh frog Rana ridibunda, in Britain. Twelve adults translocated from Hungary into Kent (Romney) in 1935 resulted rapidly in a large localized population. A further successful translocation in 1973 from Romney to Sussex (Lewes), toget...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2003.01775.x
更新日期:2003-03-01 00:00:00
abstract::We present a new approach for defining groups of populations that are geographically homogeneous and maximally differentiated from each other. As a by-product, it also leads to the identification of genetic barriers between these groups. The method is based on a simulated annealing procedure that aims to maximize the ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.2002.01650.x
更新日期:2002-12-01 00:00:00
abstract::Understanding the origin of new species is a central goal in evolutionary biology. Diverging lineages often evolve highly heterogeneous patterns of genetic differentiation; however, the underlying mechanisms are not well understood. We investigated evolutionary processes governing genetic differentiation between the h...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.15571
更新日期:2020-09-01 00:00:00
abstract::Although resolving phylogenetic relationships and establishing species limits are primary goals of systematics, these tasks remain challenging at both conceptual and analytical levels. Here, we integrated genomic and phenotypic data and employed a comprehensive suite of coalescent-based analyses to develop and evaluat...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.14504
更新日期:2018-03-01 00:00:00
abstract::Cysteine plays essential biological roles, but excessive amounts produce cellular oxidative stress. Cysteine metabolism is mainly mediated by the enzymes cysteine dioxygenase and γ-glutamylcysteine synthetase, respectively coded by the genes CDO1 and GCLC. Here we test a new hypothesis posing that the synthesis of the...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.15024
更新日期:2019-03-01 00:00:00
abstract::A long-standing issue in marine biology is identifying spatial scales at which populations of sessile adults are connected by planktonic offspring. We examined the genetic continuity of the acorn barnacle Balanus glandula, an abundant member of rocky intertidal communities of the northeastern Pacific Ocean, and compar...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2004.02225.x
更新日期:2004-08-01 00:00:00
abstract::Biological invasions generally start from low initial population sizes, leading to reduced genetic variation in nuclear and especially mitochondrial DNA. Consequently, genetic approaches for the study of invasion history and population structure are difficult. An extreme example is the Mediterranean fruit fly, Ceratit...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.1998.00351.x
更新日期:1998-05-01 00:00:00
abstract::Molecular techniques have enabled behavioural ecologists to reassess mating systems from a genetic perspective. Studies of paternity frequently reveal that mating behaviour does not always reflect parentage, and may bring to light alternative mating tactics. Here we present a comparison of behavioural and genetic meas...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.1999.00683.x
更新日期:1999-07-01 00:00:00
abstract::Several species of swallowtail butterflies (genus Papilio) are Batesian mimics that express multiple mimetic female forms, while the males are monomorphic and nonmimetic. The evolution of such sex-limited mimicry may involve sexual dimorphism arising first and mimicry subsequently. Such a stepwise scenario through a n...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.14012
更新日期:2017-03-01 00:00:00
abstract::The random amplified polymorphic DNA (RAPD) technique was employed in the haplo-diploid dioecious species Gracilaria gracilis to identify sex-linked PCR markers. Sixty-nine decamer oligonucleotide primers were tested on two bulks of DNA, one from five haploid males and the other from five haploid females. One of these...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1046/j.1365-294x.1999.00721.x
更新日期:1999-09-01 00:00:00
abstract::Achieving long-term persistence of species in urbanized landscapes requires characterizing population genetic structure to understand and manage the effects of anthropogenic disturbance on connectivity. Urbanization over the past century in coastal southern California has caused both precipitous loss of coastal sage s...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.13176
更新日期:2015-05-01 00:00:00
abstract::The zebra mussel, Dreissena polymorpha (Pallas), a bivalve species originally native to the Black and Caspian seas, has invaded Ireland in the last decade. Five microsatellite loci were used to investigate genetic diversity and population structure in 10 populations across Europe (Ireland, UK, the Netherlands and Roma...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2005.02530.x
更新日期:2005-05-01 00:00:00
abstract::Distinguishing between primary and secondary intergradation among differentiated populations, and the relative importance of drift and selection, are persistent problems in evolutionary biology. An historical perspective on population interactions can provide insight into the nature of contacts, and thus help resolve ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::Crop-wild hybridization has been documented in many cultivated species, but the ecological and genetic factors that influence the likelihood or rate that cultivar alleles will introgress into wild populations are poorly understood. Seed predation is one factor that could mitigate the spread of otherwise advantageous c...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2010.04740.x
更新日期:2010-08-01 00:00:00
abstract::The evolution of incompatibilities between eggs and sperm is thought to play important roles in establishing and maintaining reproductive isolation among species of broadcast-spawning marine invertebrates. However, the effectiveness of gametic isolation in initiating the speciation process and/or in limiting the intro...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2009.04094.x
更新日期:2009-03-01 00:00:00
abstract::Black rats are major invasive vertebrate pests with severe ecological, economic and health impacts. Remarkably, their evolutionary history has received little attention, and there is no firm agreement on how many species should be recognized within the black rat complex. This species complex is native to India and Sou...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/mec.12149
更新日期:2013-02-01 00:00:00
abstract::Dispersal plays a prominent role in most conceptual models of community assembly. However, direct measurement of dispersal across a whole community is difficult at ecologically relevant spatial scales. For cryptic organisms, such as fungi and bacteria, the scale and importance of dispersal limitation has become a majo...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2012.05666.x
更新日期:2012-08-01 00:00:00
abstract::Mutation rates at microsatellites tend to increase with the number of repeats of the motif, leading to higher levels of polymorphism at long microsatellites. To standardize levels of diversity when microsatellites differ in size, we investigate the relationship between tract length and variation and provide a formula ...
journal_title:Molecular ecology
pub_type: 杂志文章
doi:10.1111/j.1365-294X.2005.02446.x
更新日期:2005-03-01 00:00:00