Molecular cloning and characterization of WD40-repeat protein from Clonorchis sinensis.

Abstract:

:WD40-repeat proteins have four to eight repeating units flanked by Gly-His (GH) and Trp-Asp (WD) at both termini and folds into a beta-propeller. A polypeptide deduced from a Clonorchis sinensis cDNA clone analyzed to have seven WD40-repeats and predicted to form a beta-propeller (CsWD1). The CsWD1 protein was expressed stage-specifically in the metacercariae and localized in the tegumental syncytium. The CsWD1 protein is suggested to serve as a platform for interacting partner proteins in the tegumental syncytium of C. sinensis metacercariae.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Cho PY,Kim TI,Yoo WG,Li S,Hong SJ,Kim TY,Park YS,Song KY,Choi MH,Hong ST,Chung YJ,LoVerde PT,Osman A

doi

10.1007/s00436-007-0721-6

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

53-6

issue

1

eissn

0932-0113

issn

1432-1955

journal_volume

102

pub_type

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