Abstract:
BACKGROUND:The independent effects of numerous circulating inflammatory cytokines and inflammatory associated blood cells on reendothelialization and restenosis after PCI has been elucidated, whereas the blood circulation's general effect on restenosis is still pending. Thereby, author investigated the impact of blood circulation on reendothelialization, restenosis and atrovastatin's restenosis prevention effects. METHODS AND RESULTS:70 SD rats were divided equally in 7 groups: sham operation group, deendothelialization group, atrovastatin treatment group, occlusion group, occlusion and deendothelialization group, atrovastatin treatment after occlusion and deendothelialization group, and immediate sacrifice (after deendothelialization) group. The carotid model of deendothelialization by balloon and (or) thromboembolism occlusion was established, and 4 weeks after balloon injury, the reendothelialization ratio and restenosis ratio of each subjects were observed. The outcomes revealed that there is a natural self-repair phenomenon, featured as low level reendothelialization and restenosis inhibition, which can be significantly augmented under atrovastatin treatment. Yet when the blood circulation discontinued, not only the self-repair process, but also atrovastatin's beneficial effects on reendothelialization and restenosis disappeared. SPSS analysis revealed that there was inverse correlation between reendothelialization and restenosis. CONCLUSIONS:Blood circulation not only per se generally promote reendothelialization and inhibits restenosis, but also serves as a necessary pathway for atrovastatin exerting therapeutic effects on reendothelialization and restenosis; Accelerating reendothelialization is a promising approach of restenosis prevention.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Sun ZS,Zhou SH,Guan Xdoi
10.1016/j.ijcard.2007.05.116subject
Has Abstractpub_date
2008-08-18 00:00:00pages
261-8issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(07)01202-8journal_volume
128pub_type
信件abstract::Lipomatous metaplasia of myocardium after myocardial infarction (MI) is less reported, and the exact prevalence and clinical implications of this phenomenon are unclear. A case of lipomatous metaplasia after MI evaluated with cardiovascular magnetic resonance (CMR) and computed tomography (CT) is presented. The presen...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.07.094
更新日期:2007-01-31 00:00:00
abstract:BACKGROUND:The trends in the IHD mortality rates vary widely across countries, reflecting the heterogeneity in the variation of the exposure to the main risk factors and in the access to different management strategies among settings. We aimed to identify model-based patterns in the time trends in IHD mortality in 50 c...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.11.004
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:To describe the derivation and validation of a novel echocardiographic metric for prediction of left ventricle thrombus (LVT). METHODS:Computational fluid dynamic modeling using cardiac CT images was used to derive a novel echocardiography-based metric to predict the presence of LVT. We retrospectively revi...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.10.079
更新日期:2017-01-15 00:00:00
abstract:BACKGROUND:The role of programmed ventricular stimulation (PVS) in patients with idiopathic dilated cardiomyopathy (DCM) and syncope receiving implantable cardioverter-defibrillators (ICD) remains controversial. METHODS AND RESULTS:Between 1994 and July 2002, 20 patients with DCM and syncope underwent PVS and ICD impl...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,评审
doi:10.1016/j.ijcard.2003.12.012
更新日期:2005-02-28 00:00:00
abstract::Unraveling the mechanisms underlying Takotsubo (TTS) leads to question the current inclusion of the condition within the spectrum of cardiomyopathies. Indeed, the clinical presentation and pathophysiology of TTS clearly differ from cardiomyopathies, i.e. diseases of heart muscle unexplained by abnormal loading conditi...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2017.12.009
更新日期:2018-03-01 00:00:00
abstract::A boy underwent total transcatheter occlusion of a patent arterial duct six years after successful balloon angioplasty of a native coarctation of the aorta. After successful implantation of a 12 mm device in the patent arterial duct there was no gradient across the descending aorta and five hours later there was no re...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90066-c
更新日期:1992-04-01 00:00:00
abstract::A rare combination of primary cardiac amyloidosis and bone amyloidosis is described in a 39-year-old female. The presenting features were restrictive heart disease and a destructive bone lesion. The diagnosis was confirmed with the help of endomyocardial and bone biopsy. ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(89)90080-6
更新日期:1989-02-01 00:00:00
abstract::Clear guidelines are lacking for the management of the clinical pattern of first-episode type atrial fibrillation (AF). We retrospectively analysed the clinical evolution of patients with self-limited first episode AF identified from among from 200 patients who had been hospitalised in our cardiology ward with AF. Of ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.08.090
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Patent foramen ovale (PFO) closure after a cryptogenic cerebral ischemic event is a routinely procedure. The most used device is Amplatzer™ PFO Occluder 25 mm, but PFOs with complex anatomy require larger device for closure. We compared Amplatzer™ Septal Occluder (ASO) device versus Amplatzer™ PFO Occluder 3...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.10.053
更新日期:2019-03-15 00:00:00
abstract:BACKGROUND:Takotsubo syndrome is an acute cardiovascular condition that predominantly affects women. In this study, we compared patients with takotsubo syndrome and those with acute myocardial infarction with respect to patient characteristics, angiographic findings, and short- and long-term mortality. METHODS:From th...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2015.03.162
更新日期:2015-04-15 00:00:00
abstract:BACKGROUND:Coronary artery spasm (CAS) is known to be a risk factor of acute coronary syndrome and angina pectoris. However, there is no currently available data with larger study population regarding long-term clinical outcomes of CAS in real world clinical practice. OBJECTIVES:We evaluated the prevalence of CAS and ...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.02.021
更新日期:2015-04-01 00:00:00
abstract::A 41-year-old woman with no modifiable coronary risk factors presented with a progressive exertional dyspnea. Chest radiography showed an enlarged cardiac silhouette with reinforced pulmonary vasculature in bilateral lower lung fields and both pleural effusion. Echocardiography revealed a dilated, globally hypokinetic...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2006.07.194
更新日期:2007-02-07 00:00:00
abstract:BACKGROUND:Geranylgeranylacetone (GGA) has been reported up-regulating heat shock protein (HSP) expression, and protecting against atrial remodeling. This study aimed to investigate the effects of GGA on atrial electrophysiology and inducibility of atrial fibrillation (AF) in heart failure (HF) model. METHODS AND RESU...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.06.072
更新日期:2013-10-09 00:00:00
abstract:BACKGROUND:Exercise electrocardiography in asymptomatic adults has been criticized because of relatively poor accuracy predicting future heart disease risk, but studies may have been too short. We investigated if integrated analysis of graded exercise tolerance tests (GXT) predicted long-term coronary heart disease (CH...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2014.12.026
更新日期:2015-02-15 00:00:00
abstract:BACKGROUND:Hypertension (HTN) is the most prevalent co-morbidity among atrial fibrillation (AF) patients; the relationship between the two is bidirectional, with an incremental effect on adverse outcomes. PURPOSE:To study clinical features, treatment patterns and 1year outcomes amongst AF patients with HTN in the EURO...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.10.092
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:It is known that coronary heart surgery leads to varying degrees of cardiac autonomic derangement, clinically detectable as depression of heart rate variability (HRV) parameters. Few studies report that also surgical replacement of the aortic valve (SAVR) may lead to HRV abnormalities, while very little is k...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2015.06.004
更新日期:2015-10-15 00:00:00
abstract:UNLABELLED:Direct intramyocardial injection of mesenchymal stem cells (MSCs) improves left ventricular ejection fraction (LVEF) and may increase ventricular arrhythmia in hearts with myocardial infarction (MI). We hypothesized that intravenous MSCs given early after acute MI would engraft in injured myocardium, improve...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.07.036
更新日期:2006-08-10 00:00:00
abstract:BACKGROUND:The risk of cardiovascular disease is notably increased in patients with chronic kidney disease (CKD) and cannabinoid receptor type 1 (CB1R) plays an important role in the development of uremic cardiomyopathy. However, the molecular mechanism underlying the uremic toxin-induced upregulation of CB1R remains e...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2017.11.086
更新日期:2018-02-01 00:00:00
abstract::With the advent of transesophageal echocardiography (TEE), thrombi of the aorta are becoming increasingly recognized as possible sources of systemic emboli. This report describes a 58-year-old woman with multiple unexplained peripheral emboli. A giant thrombus of the descending aorta has been identified as the source ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/s0167-5273(02)00509-0
更新日期:2003-06-01 00:00:00
abstract:BACKGROUND:Dyspnea on exertion is common to both heart failure (HF) and chronic obstructive pulmonary disease (COPD), and it is important to discriminate whether symptoms are caused by HF or COPD in clinical practice. The ventilatory equivalent for carbon dioxide (V̇E/V̇CO2) slope and V̇E intercept (a reflection of pul...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.09.007
更新日期:2019-01-01 00:00:00
abstract::Myocardial ischaemia and reperfusion cause dysfunction of the coronary vasculature leading to a sustained reduction in coronary blood flow and an impairment of responses to both endothelium-dependent and endothelium-independent vasodilators. In contrast, when previously ischaemic arteries are removed from the myocardi...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(97)00246-5
更新日期:1997-12-31 00:00:00
abstract:AIM:A meta-analysis and review of the evidence was conducted to determine the efficacy of aquatic exercise training for individuals with heart failure compared to traditional land-based programmes. METHODS:A systematic search was conducted for studies published prior to March 2014, using MEDLINE, PUBMED, Cochrane Libr...
journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijcard.2015.03.095
更新日期:2015-01-01 00:00:00
abstract::Andersen–Tawil syndrome (ATS) is a rare hereditary multisystem disorder. Ventricular arrhythmias, periodic paralysis and dysmorphic features constitute the classic triad of ATS symptoms. The expressivity of these symptoms is, however, extremely variable, even within single ATS affected families, and not all ATS patien...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2013.10.010
更新日期:2013-12-05 00:00:00
abstract::To evaluate the effect of ST-segment measurement point on diagnostic performance of the ST-segment/heart rate (ST/HR) hysteresis, the ST/HR index, and the end-exercise ST-segment depression in the detection of coronary artery disease, we analysed the exercise electrocardiograms of 347 patients using ST-segment depress...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/s0167-5273(97)00157-5
更新日期:1997-10-10 00:00:00
abstract::There is a high prevalence of coronary artery disease (CAD) in patients with left bundle branch block (LBBB); however there are many other causes for this electrocardiographic abnormality. Non-invasive assessment of these patients remains difficult, and all commonly used modalities exhibit several drawbacks. This ofte...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2015.01.084
更新日期:2015-04-01 00:00:00
abstract::A distal location of the atherosclerotic plaque is one of the most powerful predictors of adverse events after left main angioplasty. However, bifurcations are not alike and may differ with regards to a number of variables, including the angle of the bifurcation, the presence of a ramus, the burden of downstream coron...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2011.08.059
更新日期:2012-09-20 00:00:00
abstract:BACKGROUND:Patients with primary hyperparathyroidism (pHPT) show an increased bioelectrical risk not related to cardiovascular complications, this risk seems to persist after surgery and this last finding is still controversial and probably related to follow-up length. METHODS:The aim of the study is to evaluate QT pa...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2008.11.067
更新日期:2010-05-28 00:00:00
abstract::Pulse wave analysis (PWA) by radial arterial tonometry is receiving increasing attention for the assessment of central vascular compliance in younger patients. We present five PWA studies performed prospectively on a patient with severe coronary artery disease, and find that the measures of central augmented pressure ...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2009.03.015
更新日期:2011-05-19 00:00:00
abstract:BACKGROUND:The performance of the GRACE, HEART and TIMI scores were compared in predicting the probability of major adverse cardiac events (MACE) in chest pain patients presenting at the emergency department (ED), in particular their ability to identify patients at low risk. METHODS:Chest pain patients presenting at t...
journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ijcard.2016.10.080
更新日期:2017-01-15 00:00:00
abstract:BACKGROUND:Our study aimed to compare three different percutaneous coronary intervention (PCI) approaches: culprit-only (COR) and complete (CR) revascularization - categorizing into immediate (ICR) or staged (SCR). METHODS:We searched 13 databases for randomized controlled trials. Articles were included if they compar...
journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ijcard.2017.06.027
更新日期:2017-10-01 00:00:00