[Cold chain maintenance in vaccines: a systematic review].

Abstract:

OBJECTIVE:Systematic immunization programmes mostly depend on the correct maintenance and manipulation of the vaccines to be used, i.e. perfect maintenance of the cold chain. Therefore, we decided to carry out a systematic review of the literature on the cold chain and vaccines, to identify daily practices in vaccine sites. METHODS:A literature search was performed in the main medical databases for documents published between 1990 and 2005, including those performed by means of a survey and/or inspection of vaccine sites that provided the following data: a designated health officer, availability of a thermometer with maximums and minimums, refrigerator temperature at the time of the visit, and temperature control and registration. For all the variables, the mean prevalence was calculated with a 95% confidence interval. RESULTS:Three hundred seventy-seven articles were found; 31 were initially selected and 13 were finally included. In 72.21% of the vaccine points, there was an officer responsible for the vaccines, but only 61.43% knew the optimal temperature range. Fifty-five percent of these points had a thermometer with maximums and minimums and only 26.88% carried out temperature controls and registrations at least once per day. CONCLUSION:Important shortfalls were detected in cold chain maintenance in all selected articles, jeopardizing the effectiveness and efficiency of immunization programs.

journal_name

Gac Sanit

journal_title

Gaceta sanitaria

authors

Ortega Molina P,Astasio Arbiza P,Albaladejo Vicente R,Arrazola Martínez P,Villanueva Orbáiz R,Ramón de Juanes Pardo J

doi

10.1157/13108510

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

343-8

issue

4

eissn

0213-9111

issn

1578-1283

pii

13108510

journal_volume

21

pub_type

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