Cyclosporine A prevents neurological deterioration of patients with SAH--a preliminary report.

Abstract:

:In the present study we found that the neurological outcome in patients anaesthetized for early clipping (up to 72 h after SAH) of a ruptured aneurysm and treated with cyclosporine A was significantly better than the neurological state of control patients without immuno-suppressive treatment. The results justify the presumption that auto-immune reactions are involved in the deterioration of the postoperative neurological state of patients with SAH after rupture of an intracranial aneurysm. Supplementing a standard surgical and pharmacological treatment with cyclosporine A seems to reduce the undesirable neurological consequences of the immunologically, induced vascular disturbance after SAH.

journal_name

Acta Neurochir (Wien)

journal_title

Acta neurochirurgica

authors

Ryba M,Pastuszko M,Iwanska K,Bidzinski J,Dziewiecki C

doi

10.1007/BF01402450

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

25-7

issue

1-2

eissn

0001-6268

issn

0942-0940

journal_volume

112

pub_type

临床试验,杂志文章,随机对照试验
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    更新日期:2009-12-01 00:00:00

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    authors: Kirchner M

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    doi:10.1007/978-3-7091-8444-8_30

    authors: Bouchard G

    更新日期:1976-01-01 00:00:00

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    更新日期:2019-04-01 00:00:00

  • Timing of surgery for ruptured supratentorial arteriovenous malformations.

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    pub_type: 杂志文章

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    更新日期:2017-11-01 00:00:00

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    pub_type: 杂志文章

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    authors: Viale GL,Cossu M,Cella F,Balestrero M,Rossi A,Masoni D

    更新日期:1994-01-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2019-07-01 00:00:00

  • Treatment of cavernous malformations in supratentorial eloquent areas: experience after 10 years of patient-tailored surgical protocol.

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    authors: Sanmillan JL,Lopez-Ojeda P,Fernández-Conejero I,Fernández-Coello A,Plans G,Ali-Ciurana Y,Gabarrós A

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  • Pain and brachial plexus lesions: evaluation of initial outcomes after reconstructive microsurgery and validation of a new pain severity scale.

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    pub_type: 杂志文章

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    journal_title:Acta neurochirurgica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1007/BF01420508

    authors: Baum H,Lüdecke DK,Herrmann HD

    更新日期:1986-01-01 00:00:00

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    pub_type: 杂志文章

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    authors: Cecchi PC,Musumeci A,Faccioli F,Bricolo A

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    pub_type: 杂志文章

    doi:10.1007/s007010050148

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    更新日期:1998-01-01 00:00:00

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    pub_type: 杂志文章

    doi:10.1007/BF01400530

    authors: Unsgaard G,Helseth E,Vik R,Dalen A

    更新日期:1988-01-01 00:00:00

  • Cerebral aneurysm neck diameter is an independent predictor of progressive occlusion after stent-assisted coiling.

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    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

    doi:10.1007/s00701-017-3199-8

    authors: Nakazaki M,Nonaka T,Nomura T,Onda T,Yonemasu Y,Takahashi A,Hashimoto Y,Honda O,Oka S,Sasaki M,Daibo M,Honmou O

    更新日期:2017-07-01 00:00:00

  • The endoscope-assisted supraorbital "keyhole" approach for anterior skull base meningiomas: an updated meta-analysis.

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    journal_title:Acta neurochirurgica

    pub_type: 杂志文章

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    authors: Khan DZ,Muskens IS,Mekary RA,Zamanipoor Najafabadi AH,Helmy AE,Reisch R,Broekman MLD,Marcus HJ

    更新日期:2020-09-05 00:00:00

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    journal_title:Acta neurochirurgica

    pub_type: 临床试验,杂志文章

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    pub_type: 杂志文章,多中心研究

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    更新日期:2017-05-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2012-06-01 00:00:00

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    pub_type: 杂志文章

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    更新日期:2012-11-01 00:00:00

  • Effect of weekend admission on in-hospital mortality and functional outcomes for patients with acute subarachnoid haemorrhage (SAH).

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    doi:10.1007/s00701-016-2746-z

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  • Neurosurgical intensive care improves outcome after severe head injury.

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    doi:10.1007/BF01809553

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    doi:10.1007/BF01400583

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