Abstract:
PURPOSE:Complete yet safe resection close to motor areas in medically intractable epilepsy requires functional information. New deficit may occur despite preservation of motor cortex, e.g., through vascular compromise. Here, we explore for the first time the feasibility, safety, and the clinical value of continuous motor-evoked potential (MEP) monitoring in focal epilepsy surgery. METHODS:High-frequency stimulation for MEP monitoring was performed during 100 consecutive lesionectomies critically related to motor areas and pathways. Extraoperative motor cortex mapping was performed in 27 of these cases via chronically implanted subdural grid electrodes. MEP monitoring results, postoperative motor outcome, and seizure control were correlated in a prospective observational design. RESULTS:Reliable MEP monitoring was achieved in 86 cases. Young age was the only discernible cause of unsuccessful recordings. Seizures from cortex stimulation did not occur. MEP changes (36%) predicted new motor deficit (17%) in all cases except purely cortical lesions. MEP changes predicted occurrence and permanence of new pareses. New deficit was significantly more frequent without (as compared with) successful monitoring (43% vs. 17%); permanently severe pareses from ischemia occurred only without MEPs (21% vs. 0%). Complete seizure control was significantly more frequent in successfully monitored cases (60% vs. 31%). Even with extraoperative motor mapping, severe paresis occurred only among cases with unsuccessful MEPs. CONCLUSIONS:Continuous MEP monitoring in epilepsy surgery is feasible and safe. It reflects motor function complementarily to the localizing motor mapping results. Successful MEP monitoring correlates with unimpaired motor outcome and full seizure control.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Neuloh G,Bien CG,Clusmann H,von Lehe M,Schramm Jdoi
10.1007/s00701-010-0675-9subject
Has Abstractpub_date
2010-08-01 00:00:00pages
1307-14issue
8eissn
0001-6268issn
0942-0940journal_volume
152pub_type
杂志文章abstract::Meningiomas are tumors arising from the meninges and represent the most frequent central nervous system tumors in adults. Recent large-scale genetic studies and preclinical meningioma mouse modelling led to a better comprehension of meningioma development and suggested evidences of close relationships between meningea...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-020-04650-w
更新日期:2021-01-01 00:00:00
abstract::The feline infusion model of brain edema was used to evaluate the pathophysiological effects of 0.6 ml infusions of autologous serum protein (66%), human serum protein (66%), human glioma cyst fluid and a tissue culture medium (TCM) on the structure and function of the forebrain white matter. These infusions increased...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112037
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Pituitary apoplexy is a rare and life-threatening complication occurring in 0.6-10.5% of all cases of pituitary adenomas. Although the association between pituitary apoplexy and visual dysfunction has been recognized for a long time, the optimal management of this problem still remains controversial. The pur...
journal_title:Acta neurochirurgica
pub_type: 历史文章,杂志文章,评审
doi:10.1007/s00701-009-0595-8
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:The supracerebellar infratentorial approach is a commonly used route in neurosurgery. It provides a narrow and deep corridor to the dorsal midbrain and pineal region. The authors describe a surgical technique to expand the operative corridor and the surgeon's working angles during this approach. METHODS:Thi...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1844-4
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND/PURPOSE:Increased slow-wave activity in intracranial pressure (ICP) signifies an exhausted cerebrospinal compensatory reserve across a range of conditions. In this study, we attempted to describe synchronisation between slow waves of ICP and of near-infrared spectroscopy (NIRS) variables during controlled el...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0748-9
更新日期:2010-10-01 00:00:00
abstract::The ventriculographic findings of a severe ascending transtentorial herniation that occurred after shunting in an infant with a posterior fossa tumour are described. ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405337
更新日期:1978-01-01 00:00:00
abstract::Does the absolute value of the stump pressure (post-occlusion back pressure) become a useful index of a good collateral circulation? The authors continuously monitored the mean arterial pressure before, during and after 20-minute balloon test occlusion in 24 patients. The stump pressure was then compared with the resu...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411175
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Increasingly, biomarkers have been identified that correlate with improved overall and progression-free survival (OS and PFS) in glioblastoma, including MGMT methylation status and mutations in the IDH1 gene. In this study, we investigated the clinical and biological factors associated with long-term surviva...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-016-2928-8
更新日期:2016-10-01 00:00:00
abstract::12 patients, 10 women and 2 men, were operated on for removal of a jugular foramen neurinoma. Removal was total in 11 cases and operative mortality was 16.6%. As there are no clinical or instrumental signs that permit sure distinction between these tumours and those of the cerebellopontine angle, only a thorough radio...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01406293
更新日期:1975-01-01 00:00:00
abstract::Ki-67 antigen is used as a marker of proliferative activity that is linked to growth rate, invasiveness and prognosis of pituitary adenomas. So far the distribution of Ki-67 index within an individual adenoma has not been investigated. If Ki-67 antigen expression differs significantly within an individual pituitary ad...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0390-5
更新日期:2004-12-01 00:00:00
abstract::The results of electro-oculographic recordings made after caloric vestibular stimulation (C.O.G.) in severe head injured patients are discussed. It was found that: 1. The C.O.G. correlates with the state of consciousness of the patients. 2. The rate of improvement of the C.O.G. correlates with the rate of the clinical...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405860
更新日期:1976-01-01 00:00:00
abstract:BACKGROUND:Rathke's cleft cyst (RCC) with significant squamous and/or stratified epithelium including smooth transition from single cuboidal to squamous epithelium (tRCC) is rare and possibly represents an intermediate form to craniopharyngioma. METHODS:Twelve patients with histologically confirmed tRCC were retrospec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1593-9
更新日期:2013-06-01 00:00:00
abstract::The feasibility of diagnosing the malignancy and viability of intraparenchymal brain tumours using Gd-DTPA, enhanced and unenhanced T1-weighted MRIs was investigated. The relationship between the Gd-DTPA enhancement pattern, the growth fraction (GF) determined by using the anti-bromide-oxyuridine (BrdU) monoclonal ant...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01400619
更新日期:1992-01-01 00:00:00
abstract::We investigated the role of plasminogen activators (PAs) and their inhibitor (plasminogen activator inhibitor-1, PAI-1) in human brain tumours. The amounts of urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA), and plasminogen activator inhibitor-1 (PAI-1), and the activity of u-PA a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050112
更新日期:1998-01-01 00:00:00
abstract::The purpose of the present study is to evaluate retrospectively the effects of several intra-operative manipulations on the results of foramen magnum decompression (FMD) in patients having syringomyelia associated with type I Chiari malformation. Seventy-five patients having syringomyelia associated with Chiari I malf...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050175
更新日期:1998-01-01 00:00:00
abstract::Therapy for vasogenic brain oedema (VBE) is still an unsolved problem. Experimental work with the aim of establishing an oncotherapeutic option is presented. VBE is performed by focal freeze injury in rats. Using a stereotactic head holder hypo- or hyperosmolar human serum albumin is administered via the intraventricu...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01412002
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Microvascular decompression (MVD) for hemifacial spasm (HFS) has been popular, but it may take enough time to master this special operative technique and procedure. This may induce uneven distribution of the number of MVD operations in each institute, possibly resulting in an overall unsatisfactory quality o...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1724-y
更新日期:2013-09-01 00:00:00
abstract::Fifty-one cases of posterior fossa haemangioblastoma have been seen in our department over a period of 23 years. Seven cases were associated with spinal cord lesions and one with a supratentorial lesion. There were 22 cases of Lindau's disease (43%). The onset was earlier and recurrences commoner than in isolated case...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02112026
更新日期:1993-01-01 00:00:00
abstract:UNLABELLED:OBJECTIVE, BACKGROUND: Cerebral angiography, performed within 24 hr of aneurysmal rupture, carries an increased risk of rebleeding. We have investigated the rerupture rate during angiography procedures under deep general anesthesia and the factors that contribute to rebleeding. METHODS:We divided 69 patient...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0541-3
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Vestibular schwannoma (VS) is a benign tumor originating from the vestibulocochlear nerve. The optimal treatment strategy is debated, since surgery may result in iatrogenic facial nerve injury. We report the results of VS surgery in a population-based unselected cohort in a center with access to Cyber Knife ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-04055-4
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:This study was aimed at the evaluation of the relationship between genetic polymorphisms of catechol-O-methyltransferase (COMT) (rs4680:A > G-Val158Met, rs6269:A > G, rs4633:C > T, rs4818:C > G) and pain sensitivity after lumbar discectomy. METHODS:All patients had one-level symptomatic disc herniation from...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1895-6
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The generally accepted indications for carotid endarterectomy are the clinical picture and degree of per cent stenosis of the carotid artery. Despite the fact that stenosis measurement is defined, the methods vary considerably. The correlation of particular methods, especially angiography and duplex sonograp...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0279-3
更新日期:2004-07-01 00:00:00
abstract::In order to further elucidate the pathogenesis of the direct carotid cavernous fistulas (dCCF) clinical, patho-anatomical, and physico-mechanical studies were performed. In 27 of 42 patients the dCCF were found to be localized in the segment C4 (according to Teufel, 12), in 13 patients in segment C2 and in only 2 pati...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01808537
更新日期:1994-01-01 00:00:00
abstract::The effect of acetazolamide on the cerebral blood flow was studied in gerbils with unilateral carotid ligation. According to the effect of ligation the animals were divided into three groups: first group-the reduction more than 70%, second-CBF reduction 30-70% and the third group-CBF reduction less than 30%. The effec...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411729
更新日期:1996-01-01 00:00:00
abstract::We report a 2.5-year-old boy with Saudi variant of multiple sulfatase deficiency (MSD or Austin's disease). He presented with the features of cervical cord compression and a severe form of hydrocephalus. The former was due to a thickened posterior arch of the atlas and the latter from a narrow foramen magnum and menin...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01401468
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Oculomotor cistern extension (OMCE) of pituitary adenoma through the oculomotor triangle may be one of the major characteristics of multi-lobulated adenoma. The OMCE may be hard to remove only through the endonasal approach. METHOD:We applied the simultaneous combined supra-infrasellar approach to remove pi...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-019-03869-6
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:It is essential to have easy to use, reliable tools to assess and compare facial function for clinical records, audit and research purposes. In this study, two different techniques were examined, Hand held calipers (HHC, as described by Burres), and computerised analysis of digital photographs (CAOP) using A...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0904-4
更新日期:2006-12-01 00:00:00
abstract::The diagnostic and prognostic values of quantitative isotope ventriculography (QIV), lumbar isotope cisternography (LIC), pneumoencephalography (PEG), and continuous intraventricular pressure recording (CIP) were assessed on the basis of the clinical course in 160 patients suspected of having acquired hydrocephalus. T...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01430586
更新日期:1979-01-01 00:00:00
abstract::The authors report two unusual cases in which a malignant astrocytoma developed at the site of the excision of an earlier medulloblastoma. While the precise etiology of these astrocytic tumours was unproven, theories of the origins of the second tumours, particularly in relation to the basic nature of medulloblastomas...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010170048
更新日期:2001-01-01 00:00:00
abstract::One case of a pontine haematoma with clinical symptoms of cerebellopontine angle tumour is described. The haematoma was successfully evacuated, and preoperative neurological deficits disappeared except for minimal right fifth nerve palsy. The pathological specimen was diagnosed as arteriovenous malformation. Lateropon...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF02055855
更新日期:1983-01-01 00:00:00