Abstract:
BACKGROUND:Multicentric WHO grade II gliomas constitute a rare entity. Their pathogenesis and treatment are still a matter of debate. OBJECTIVE:We present a 23 year-old female with two synchronous but separate WHO grade II oligodendrogliomas in the temporal and frontal lobes. CLINICAL FEATURES:The two lesions showed independent evolution, requiring surgical treatment at different stages. For a recurrence of the disease at the frontal site, a temozolomide chemotherapy regimen was commenced with a favourable response. After 7 years follow-up, the patient is free of neurological symptoms and enjoys a normal life. CONCLUSION:The problems concerning the pathophysiology, diagnosis and treatment of this condition are discussed. On the basis of our results, we suggest that an active therapeutic strategy, by combining multiple surgical procedures and complementary treatment, should be systematically considered in multicentric WHO grade II gliomas, as in similar unifocal neoplasms.
journal_name
Acta Neurochir (Wien)journal_title
Acta neurochirurgicaauthors
Vergani F,Sanson M,Duffau Hdoi
10.1007/s00701-009-0306-5subject
Has Abstractpub_date
2009-12-01 00:00:00pages
1699-704issue
12eissn
0001-6268issn
0942-0940journal_volume
151pub_type
杂志文章abstract:BACKGROUND:Fenestrations of intracranial arteries are variants resulting from incomplete fusion of vessels during development with unknown clinical significance. They are best visualised with 3D rotational angiography (3DRA). OBJECTIVE:In a prospective consecutive series of patients with suspected aneurysms, 3DRA was ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-012-1587-7
更新日期:2013-02-01 00:00:00
abstract::The Spanish National Committee for Neurosurgery has recently approved a new training programme which will shortly replace the former programme, which dates from 1984. The object of this report was to evaluate training in neurosurgery in Spain under the extant programme as perceived by the residents themselves. Assessm...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-004-0459-1
更新日期:2005-04-01 00:00:00
abstract::Sporadic vestibular schwannoma (VS) causes unilateral hearing loss, tinnitus, vertigo and unsteadiness. In many cases, the tumour size may remain unchanged for many years following diagnosis, which is typically made by MRI. In the majority of cases the tumour is small, leaving the clinician and patient with the option...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-007-1179-0
更新日期:2007-01-01 00:00:00
abstract::Cerebral developmental venous anomalies (DVAs) are variations of venous vascular anatomy related to an underdevelopment of either the superficial or deep venous emissary system, resulting in a dilated transmedullary vein fed by multiple smaller venous radicles responsible for drainage of normal brain parenchyma. While...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s00701-020-04213-z
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND/PURPOSE:Increased slow-wave activity in intracranial pressure (ICP) signifies an exhausted cerebrospinal compensatory reserve across a range of conditions. In this study, we attempted to describe synchronisation between slow waves of ICP and of near-infrared spectroscopy (NIRS) variables during controlled el...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0748-9
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:In dealing with cases of oedematous brain, relaxation during the transsylvian approach to supratentorial aneurysms has been accomplished by ventricular drainage by using the anatomic point defined by Dr. Paine. However, we have experienced patient complications when using this point. We propose a novel anatom...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-007-1281-3
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Public engagement has become one of the most effective tools in gaining feedback and perspectives from members of the public, involving patients with decisions, and inspiring young people to carry the medical profession forwards. Brainbook is a multi-platform, social media-based resource that was created spe...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-018-3757-8
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Although 30-50 % of patients with brain tumors experience epileptic seizure as the presenting clinical symptom, and another 10-30 % are at risk for developing epilepsy in the later stages of the disease, the mechanisms of tumor-related epileptogenesis are poorly understood. We used magnetoencephalography (ME...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1781-2
更新日期:2013-08-01 00:00:00
abstract::Cervicocephalic fibromuscular dysplasia (FMD) is an idiopathic, non-inflammatory and non-atherosclerotic arteriopathy which usually affects small- and medium-sized cervical arteries distributed at the atlas and axis interspace. Few cervicocephalic FMD patients are associated with multiple intracranial aneurysms which ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-010-0778-3
更新日期:2010-12-01 00:00:00
abstract::The levels of circulating immune complexes (CIC) were assayed in the sera of 109 patients with intracranial space occupying lesions. The CIC levels were significantly increased in all the brain tumours. After treatment, the CIC levels were still significantly increased when compared to the controls but showed no chang...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01420068
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:Modern magnetic resonance imaging (MRI) diagnosis of Tolosa-Hunt syndrome rests upon demonstration of cavernous sinus abnormalities. We present a case of Tolosa-Hunt syndrome who has no abnormal mass lesion in the cavernous sinuses on MRI but with a diagnostic lesion on magnetic resonance angiography (MRA). ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010170112
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:Radiosurgical treatment of brain lesions near motor or language eloquent areas requires careful planning to achieve the optimal balance between effective dose prescription and preservation of function. Navigated brain stimulation (NBS) is the only non-invasive modality that allows the identification of funct...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2079-8
更新日期:2014-06-01 00:00:00
abstract::We report a case of fibrosarcoma arising in the pineal of a 36-year-old female patient. She died at the age 43 following biopsy, radiation therapy, tumor resection, chemotherapy, and stereotactic radiosurgery. Light microscopic study of all tissues obtained, including immunohistochemistry and electron microscopy of su...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s701-002-8277-6
更新日期:2002-01-01 00:00:00
abstract::Retroclival arachnoid cysts are rarely reported. A 40-year-old woman had a sudden onset of occipitocervical pain. Magnetic resonance imaging (MRI) revealed a cystic mass lesion located in the retroclival region and complicated with intracystic haemorrhage. At operation, by a right lateral suboccipital approach, an old...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0381-7
更新日期:2010-01-01 00:00:00
abstract::Unstable fracture dislocations due to torn ligaments, fractures of both articular processes, or detachments of entire vertebral arches from vertebral bodies still pose the problem of fixation after anterior fusion. The application of internal metal plate fixation--using the small AO (ASFI) fragment equipment--is descr...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405907
更新日期:1975-01-01 00:00:00
abstract::A paraganglioma of cauda equina region is extremely rare and except for secreting tumour, the pre-operative diagnosis of paraganglioma is very difficult. Two cases of non-functional paragangliomas of the cauda equina region are reported, one was attached to the filum terminale and the other to a rootlet looking very m...
journal_title:Acta neurochirurgica
pub_type: 杂志文章,评审
doi:10.1007/s007010050269
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:This study aimed to clarify the characteristics of the basilar arteries of rabbits two and seven days after subarachnoid haemorrhage (SAH) and to investigate the influence of hypoxia on vascular responses to acetylcholine and endothelin-1. METHODS:Thirty four New Zealand white rabbits were divided into 3 gr...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-003-0024-3
更新日期:2003-07-01 00:00:00
abstract::Niravoline is a selective kappa-opioid receptor agonist. Its effect on tumour-origin brain oedema was investigated in a brain tumour model created by implantation of C6 glioma cells into the brain of Wistar rats. Five weeks after the tumour cell implantation, niravoline was administered i.v. at 1 mg/kg, a total of fou...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s007010050374
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:An intracranial in situ side to side posterior circulation procedure is performed infrequently. The scope of treatment modalities of vertebral artery-PICA aneurysms and vertebral dissections is limited due to the lack of many representations of this procedure's technical nuances. METHODS:To demonstrate the ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-013-1874-y
更新日期:2013-11-01 00:00:00
abstract::Leptomeningeal cysts are commonly seen in children usually following trauma and associated with bulging leptomeninges at the site of fracture. Intradiploic leptomeningeal cyst is an important differential for an expansile lytic lesion in the bony calvarium especially in a patient with a previous history of trauma. Her...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2660-9
更新日期:2016-02-01 00:00:00
abstract::Described are: 1. A very thin intracisternal part of the vertebral artery (0.9 mm). 2. A very rare course of the vertebral artery (dorsal to the hypoglossal nerve). 3. Rare anastomoses between the vertebral artery and the PICA. 4. A rare upwards coiling of the PICA and 5. The origin and prevertebral course of the vert...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01809336
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:In order to determine the reliability of magnetic resonance imaging (MRI) in the diagnosis and staging of carpal tunnel syndrome (CTS), the most common entrapment neuropathy, the following prospective study has been performed. METHODS:We compared clinical and electrophysiological studies in 58 cases of CTS wit...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01411366
更新日期:1996-01-01 00:00:00
abstract::In this study, which comprises 144 consecutive head injuries, the initial clinical assessment and the findings of the initial CT scan are related to the outcome. The mortality is related to the patient's level of consciousness and pupillary light reflex on admission. The disability rate (= number of disabled/number of...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01405444
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:Several studies have investigated the relation between intraoperative abnormal muscle response (AMR) findings and postoperative results in patients undergoing microvascular decompression (MVD) for hemifacial spasm (HFS). However, there is some debate over the reliability of AMR as an indicator of postoperati...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-005-0571-x
更新日期:2005-09-01 00:00:00
abstract:INTRODUCTION:Intraoperative detection of residual tumor remains an important challenge in surgery to treat gliomas. New developments in optical techniques offer non-invasive high-resolution imaging that may integrate well into the workflow of neurosurgical operations. Using an intracranial glioma model, we have recentl...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-009-0248-y
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:In patients with mass lesions near "eloquent" cortical areas different preoperative mapping techniques can be used. Two of the most widely used approaches include positron emission tomography (PET) and functional MRI (fMRI). We employed both methods in the same patients undergoing presurgical evaluation and ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-002-0992-8
更新日期:2002-09-01 00:00:00
abstract:OBJECTIVES:Ballistic injuries to peripheral nerves pose special challenges in terms of indications, timing and type of surgical intervention. The aim of the present work was to analyze our experience in the surgical treatment of peripheral nerve ballistic injuries with respect to the mechanism of injury (gunshot versus...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-014-2139-0
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Microvascular decompression (MVD) for hemifacial spasm (HFS) provides a long-term cure rate. Delayed facial palsy (DFP) is not an unusual complication, but it has only been sporadically described in the literature. The purpose of this report is to evaluate the incidence of delayed facial palsy after MVD and ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-006-0847-9
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:Close relatives (CR) of patients with severe traumatic brain injury (TBI) and high-grade subarachnoid hemorrhage (SAH) suffer extraordinary distress during the treatment: Distress may lead to persisting mental illness symptoms within the spectrum of post-traumatic stress disorder (PTSD), anxiety disorders, a...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/s00701-015-2470-0
更新日期:2015-09-01 00:00:00
abstract::Four cases of primary intraosseous meningiomas were seen among 373 cases of intracranial meningiomas operated upon in the Neurosurgical Clinic of the Krankenhaus Nordstadt, Hannover, FRG between January 1978 and December 1988. These 4 cases represent 1% of all intracranial meningiomas. Patients' age ranged between 21 ...
journal_title:Acta neurochirurgica
pub_type: 杂志文章
doi:10.1007/BF01402613
更新日期:1990-01-01 00:00:00