Intra-albumin migration of bound fatty acid probed by spin label ESR.

abstract：:T cell immunotherapies are promising options in leukemia, among which the CD19/CD3-bispecific T cell engager antibody blinatumomab (MT103) has shown high response rates at very low doses in patients with lymphoma. However, the high CD47 expression in human lymphoma cells has limited the curative effects of blinatumoma...

journal_title：Biochemical and biophysical research communications

authors： Xu L,Wang S,Li J,Li B

更新日期：2019-02-12 00:00:00

abstract：:Vinculin and meta-vinculin are related proteins that localize to adherens junctions. To facilitate studies on the biology of these proteins cDNA clones were isolated from a chick embryonic library made in lambda gt 11. Three clones, accounting for 1/2 of the vinculin message, were identified by immunological analyses ...

journal_title：Biochemical and biophysical research communications

authors： Coutu MD,Simon DJ,Brown AE,Craig SW

更新日期：1987-09-15 00:00:00

abstract：:The effect of calcitonin gene-related peptide(CGRP) on the release of atrial natriuretic peptide(ANP) was studied in spontaneously beating, isolated rat atria. CGRP stimulated the ANP release in a dose-dependent manner. When the atria were incubated with a combination of phentolamine, propranolol, and atropine, these ...

journal_title：Biochemical and biophysical research communications

authors： Yamamoto A,Kimura S,Hasui K,Fujisawa Y,Tamaki T,Fukui K,Iwao H,Abe Y

更新日期：1988-09-30 00:00:00

abstract：:Ganoderma lucidum (G. lucidum) is a popular medicinal mushroom that has been used as a home remedy for the general promotion of health and longevity in East Asia. The dried powder of G. lucidum, which was recommended as a cancer chemotherapy agent in traditional Chinese medicine, is currently popularly used worldwide ...

journal_title：Biochemical and biophysical research communications

authors： Stanley G,Harvey K,Slivova V,Jiang J,Sliva D

更新日期：2005-04-29 00:00:00

abstract：:P-selectin is a cell adhesion molecule found in platelets and endothelial cells mediating binding of leukocytes. It is stored in secretory granules and expressed at the plasma membrane after cell activation. After rapid internalisation P-selectin recycles or is degraded. The 35 amino acid cytoplasmic domain of P-selec...

journal_title：Biochemical and biophysical research communications

authors： Florian V,Schlüter T,Bohnensack R

更新日期：2001-03-09 00:00:00

abstract：:The neural crest is a transient population of multipotent progenitors contributing to a diverse array of tissues throughout the vertebrate embryo. Embryonic stem (ES) cells are able to form embryoid body and spontaneously differentiate to various lineages, following a reproducible temporal pattern of development that ...

journal_title：Biochemical and biophysical research communications

authors： Zhou Y,Snead ML

更新日期：2008-11-21 00:00:00

abstract：:Bovine pulmonary artery endothelial cells (BPAEC) were prelabeled with [3H]choline or [3H]myristic acid to selectively label endogenous phosphatidylcholine. BPAEC were stimulated with ATP and bradykinin (BK), and phospholipase D (PLD) activation was detected as a 4-fold increase in [3H]choline in cells prelabeled with...

journal_title：Biochemical and biophysical research communications

authors： Martin TW,Feldman DR,Goldstein KE,Wagner JR

更新日期：1989-11-30 00:00:00

abstract：:Polyubiquitin chains on proteins flag them for distinct fates depending on the type of polyubiquitin linkage. While lysine48-linked polyubiquitination directs proteins to proteasomal degradation, lysine63-linked polyubiquitination promotes different protein trafficking and is involved in autophagy. Here we show that p...

journal_title：Biochemical and biophysical research communications

authors： Dosemeci A,Thein S,Yang Y,Reese TS,Tao-Cheng JH

更新日期：2013-01-04 00:00:00

abstract：:The addition of the tumor-promoting phorbol 12-myristate, 13-acetate to rabbit neutrophils greatly potentiates the effect of the calcium ionophore A23187 on [3H]-arachidonic acid release and [32P]-phosphatidic acid generation. At 5 X 10(-8) M A23187, the addition of 20 ng/ml PMA potentiates the action of the ionophore...

journal_title：Biochemical and biophysical research communications

authors： Volpi M,Molski TF,Naccache PH,Feinstein MB,Sha'afi RI

更新日期：1985-04-30 00:00:00

abstract：BACKGROUND:Autophagy and apoptosis are two important regulators of cell survival, and are often observed simultaneously in response to noxious stimuli. Anoxia is a known stimulus for autophagy and apoptosis, and angiotensin (Ang) II is a major mediator of anoxic injury. However, specific responses to anoxia and Ang II ...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Dai Y,Ding Z,Khaidakov M,Mercanti F,Mehta JL

更新日期：2013-11-01 00:00:00

abstract：:Heat shock proteins are detectable in human atherosclerotic plaques, especially in endothelial cells. In this report we show by immunofluorescence that incubation "in vitro" with OxLDL is a stress capable of inducing the expression of heat shock protein 70 in both the EAhy-926 cell line and human umbilical vein endoth...

journal_title：Biochemical and biophysical research communications

authors： Zhu W,Roma P,Pellegatta F,Catapano AL

更新日期：1994-04-15 00:00:00

abstract：:Eukaryotic transcriptional activators may function, at least in part, to facilitate the assembly of the RNA polymerase II (pol II) preinitiation complex at the core promoter region through their interaction with a subset of components of the basal transcription machinery. Previous studies have shown that artificial te...

journal_title：Biochemical and biophysical research communications

authors： Huh JR,Park JM,Kim M,Carlson BA,Hatfield DL,Lee BJ

更新日期：1999-03-05 00:00:00

abstract：:The major bovine seminal plasma protein, PDC-109, binds to choline phospholipids of the sperm plasma membrane and induces an efflux of cholesterol and choline phospholipids (cholesterol efflux), which is crucial for sperm capacitation. PDC-109 also exhibits chaperone-like activity and protects target proteins against ...

journal_title：Biochemical and biophysical research communications

authors： Singh BP,Saha I,Nandi I,Swamy MJ

更新日期：2017-12-02 00:00:00

abstract：:The polyketide synthases found in a variety of plants and fungi provide a varied source of biologically active compounds of pharmacological and medicinal interest. Stilbene synthase and chalcone synthase catalyze the formation of a common tetraketide intermediate, but use different cyclization mechanisms to produce di...

journal_title：Biochemical and biophysical research communications

authors： Healy EF,Cervantes L,Nabona B,Williams J

更新日期：2018-03-18 00:00:00

abstract：:The ability to identify apoptotic cells within a complex population is crucial in the research and diagnosis of normal physiology and disease states. The Cellscan mark S (CS-S) cytometer was used in this study to detect intracellular fluorescence intensity and polarization (FI and FP) in several well-established model...

journal_title：Biochemical and biophysical research communications

authors： Zurgil N,Schiffer Z,Shafran Y,Kaufman M,Deutsch M

更新日期：2000-02-05 00:00:00

abstract：:Stimulation of human T cell line Jurkat results in rapid tyrosine phosphorylation of a 35-38 kDa protein that is found in large and buoyant detergent-resistant membrane microdomains containing also glycosylphosphatidylinositol (GPI)-anchored proteins, glycolipids and Src-family protein tyrosine kinases ("GPI-microdoma...

journal_title：Biochemical and biophysical research communications

authors： Brdiĉka T,Cerný J,Horejŝí V

更新日期：1998-07-20 00:00:00

abstract：:alpha-Acaridial [2(E)-(4-methyl-3-pentenyl)butenedial] is a novel monoterpene secreted from the house dust mites. Because of its molecular nature of a highly reactive, small lipidic compound, we addressed whether alpha-acaridial might function as a haptenic allergen that induced allergic contact dermatitis. Mice sensi...

journal_title：Biochemical and biophysical research communications

authors： Sasai T,Hirano Y,Maeda S,Matsunaga I,Otsuka A,Morita D,Nishida R,Nakayama H,Kuwahara Y,Sugita M,Mori N

更新日期：2008-10-24 00:00:00

abstract：:Insulin-like growth factor 1 receptor (IGF1R) is expressed in many types of solid tumors including non-small cell lung cancer (NSCLC), and enhanced activation of IGF1R is thought to reflect cancer progression. Epithelial-mesenchymal transition (EMT) has been established as one of the mechanisms responsible for cancer ...

journal_title：Biochemical and biophysical research communications

authors： Nurwidya F,Takahashi F,Kobayashi I,Murakami A,Kato M,Minakata K,Nara T,Hashimoto M,Yagishita S,Baskoro H,Hidayat M,Shimada N,Takahashi K

更新日期：2014-12-12 00:00:00

abstract：:A protein extract prepared from the egg shell fiber-secreting region of the oviduct of Alligator mississippiensis was assayed for the presence of receptors for estrogen and progesterone. In the presence of [3H]-estradiol-17 beta, the extract contained an estrogen-binding activity which reached equilibrium at 25 degree...

journal_title：Biochemical and biophysical research communications

authors： Vonier PM,Guillette LJ Jr,McLachlan JA,Arnold SF

更新日期：1997-03-17 00:00:00

abstract：:NADPH oxidases (NOX) - derived reactive oxygen species (ROS) contribute to oxidative injury in hypoxia-induced pulmonary arterial hypertension. This study aims to evaluate the status of NOX in endothelial progenitor cells (EPCs) under hypoxic condition and to determine whether NOX inhibitors could attenuate hypoxia-in...

journal_title：Biochemical and biophysical research communications

authors： Liu B,Ren KD,Peng JJ,Li T,Luo XJ,Fan C,Yang JF,Peng J

更新日期：2017-01-22 00:00:00

abstract：:The effect of GTP on Ca2+ uptake and release was studied in a microsomal fraction isolated from neuroblastoma x glioma hybrid NG108-15 cells. GTP did not alter the ATP-dependent initial uptake of Ca2+ but markedly enhanced the efflux of Ca2+ from microsomes. GTP-dependent Ca2+ release requires the presence of millimol...

journal_title：Biochemical and biophysical research communications

authors： Jean T,Heppel LA,Klee CB

更新日期：1989-11-15 00:00:00

abstract：:Starch branching enzyme (SBE) catalyzes the cleavage of α-1,4-linkages and the subsequent transfer of α-1,4 glucan to form an α-1,6 branch point in amylopectin. We determined the crystal structure of the rice branching enzyme I (BEI) in complex with maltopentaose at a resolution of 2.2Å. Maltopentaose bound to a hydro...

journal_title：Biochemical and biophysical research communications

authors： Chaen K,Noguchi J,Omori T,Kakuta Y,Kimura M

更新日期：2012-08-03 00:00:00

abstract：:[3H]cyclo(His-Pro) bound with high affinity (59 nM) to a single class of sites in rat liver plasma membranes, without significant tracer degradation during equilibration for 60 min at 0 degrees C. Binding was specific and saturable (3.9 pmol/mg protein), and were increased by the addition of K+, Mg++ and Na+ at optima...

journal_title：Biochemical and biophysical research communications

authors： Mori M,Yamada M,Yamaguchi M,Suzuki M,Ohshima K,Kobayashi I,Kobayashi S

更新日期：1986-01-14 00:00:00

abstract：:Light scattering pattern analysis (LSPA) was applied in the current study for accurate and sensitive detection of subtle changes in cell size, which occur in mouse thymocytes undergoing apoptosis. The decrease in cell diameter as measured by LSPA was found to be an early signal of apoptosis preceding the externalizati...

journal_title：Biochemical and biophysical research communications

authors： Shiffer Z,Zurgil N,Shafran Y,Deutsch M

更新日期：2001-12-21 00:00:00

abstract：:Bone is one of the essential target tissues of growth hormone (GH). In bone remodeling, cell-matrix attachment is important where focal adhesion kinase (FAK) is involved. FAK plays a central role in determining the shape and motility of cells in response to the extracellular matrix stimuli. In the present study, we ha...

journal_title：Biochemical and biophysical research communications

authors： Takahashi MO,Takahashi Y,Iida K,Okimura Y,Kaji H,Abe H,Chihara K

更新日期：1999-09-16 00:00:00

abstract：:Reactive oxygen species (ROS) contributes to endothelial dysfunction that is involved in the pathogeneses of hypertension. Vascular peroxidase 1 (VPO1) can utilize ROS to catalyze peroxidative reactions, possibly enhancing endothelial dysfunction. This study is to identify VPO1's involvement in endothelial dysfunction...

journal_title：Biochemical and biophysical research communications

authors： Yang L,Bai Y,Li N,Hu C,Peng J,Cheng G,Zhang G,Shi R

更新日期：2013-10-04 00:00:00

abstract：:In Wernicke's encephalopathy and thiamine deficiency (TD), the cause of this brain disorder, development of inflammation is an important aspect of the disease process. How this pathological mechanism relates to the neurologic impairment associated with TD, however, remains unclear. A key feature of the inflammatory pr...

journal_title：Biochemical and biophysical research communications

authors： Wang D,Hazell AS

更新日期：2010-11-05 00:00:00

abstract：:We prepared three peptide fragments (fg.59-105, fg.63-105 and fg.64-105) by the BrCN cleavage of mutant lysozymes where Ile58, Trp62 and Trp63 were mutated to Met, respectively. From the analysis of formation of the disulfide bonds among Cys64, Cys76, Cys80 and Cys94 in the renaturation of each peptide fragment from t...

journal_title：Biochemical and biophysical research communications

authors： Ueda T,Ohkuri T,Imoto T

更新日期：1996-11-01 00:00:00

abstract：:Despite their advantages in analysis, 4D NMR experiments are still infrequently used as a routine tool in protein NMR projects due to the long duration of the measurement and limited digital resolution. Recently, new acquisition techniques for speeding up multidimensional NMR experiments, such as nonlinear sampling, i...

journal_title：Biochemical and biophysical research communications

authors： Shigemitsu Y,Ikeya T,Yamamoto A,Tsuchie Y,Mishima M,Smith BO,Güntert P,Ito Y

更新日期：2015-02-06 00:00:00

abstract：:Processing of 37 precursor maltose-binding protein (preMBP) species by purified signal peptidase I (SPase I) was assayed. The in vitro reaction was inefficient compared to processing in Escherichia coli cells. The extent of preMBP processing in vitro was higher when SPase I was present during translation as compared t...

journal_title：Biochemical and biophysical research communications

authors： Talarico TL,Barkocy-Gallagher GA,Ray PH,Bassford PJ Jr

更新日期：1993-12-30 00:00:00