Abstract:
:Chronic hypoxia is related to many pathological conditions: aging, heart and respiratory failure, sleep apneas, smoke, chronic obstructive pulmonary disease (COPD), diabetes, hypertension and arteriosclerosis, all characterized by reductions of sleep-related erections (SREs) and by erectile dysfunction (ED). Sleep-related erections occur naturally during rapid eye movement (REM) sleep in sexually potent men. Hypoxia is also a physiological condition at altitude. The level of inspired oxygen decreases progressively with the increase of altitude; for this reason, this study was performed to evaluate the relationship of SREs with hypoxic environment. SREs have been recorded by an erectometer (RigiScan) on three mountain climbers (mean age: 32.5) during a 26-day stay at an altitude ranging from 2000 to 5600 m above sea level. Twenty-four records have been made at progressively increasing altitudes. A data analysis was carried out on a statistical mean of the three values of each variable and an analysis of variance (ANOVA) and Newman-Keuls test were carried out for multiple comparison among groups. At altitudes over 4450 m, we found lack of rigidity at 80-100% and 60-79%. Mean % of rigidity and rigidity time of 80-100% (tip and base) decreased progressively with altitude. No significant reductions were shown in rigidity time at 0-19% and at 20-39% (tip and base), of total number, of total and mean duration of SREs. Pathological rigidometric records at high altitude in sexually potent men at sea level clarify the primary role of hypoxia in physiopathological ED pathway.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Verratti V,Di Giulio C,Berardinelli F,Pellicciotta M,Di Francesco S,Iantorno R,Nicolai M,Gidaro S,Tenaglia Rdoi
10.1038/sj.ijir.3901560subject
Has Abstractpub_date
2007-09-01 00:00:00pages
496-500issue
5eissn
0955-9930issn
1476-5489pii
3901560journal_volume
19pub_type
杂志文章abstract::This cohort study aimed to assess the effect of the mode of delivery on female sexual function (FSF) after childbirth. Out of 256 primiparous women, 200 subjects that completed the study were divided into two groups; women that delivered vaginally and women that had elective cesarean section (CS). They were subjected ...
journal_title:International journal of impotence research
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更新日期:2015-05-01 00:00:00
abstract::Endothelial dysfunction, a marker for atherosclerosis and hence arterial disease, has recently been proffered as the main offender within the vascular system to predict not only the future onset of erectile dysfunction (ED) but also as the main cause of the ED. To glean more insight into whether arterial disease is in...
journal_title:International journal of impotence research
pub_type: 杂志文章
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abstract::Sexual dysfunction is a common problem of increasing incidence that is associated with multiple co-morbid conditions and chronic diseases. In heart failure, however, exact numbers are unknown, in part secondary to under-reporting and under-interrogating by health care providers. A gender-specific questionnaire was mod...
journal_title:International journal of impotence research
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更新日期:2008-01-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章,评审
doi:10.1038/ijir.2008.18
更新日期:2008-07-01 00:00:00
abstract::Erectile dysfunction (ED) due to androgen deficiency is rare in the young population. We retrospectively evaluated in this study men aged 18-40 years presenting with ED from 2015 to 2017. The International Index of Erectile Function-5 (IIEF-5) and Erection Hardness Grade Scores (EHGS) were used to assess erectile func...
journal_title:International journal of impotence research
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journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章
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更新日期:2008-03-01 00:00:00
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
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doi:10.1038/s41443-018-0029-3
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
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更新日期:1998-03-01 00:00:00
abstract::Multiple system atrophy (MSA) is a progressive neurodegenerative disease characterized by parkinsonism and cerebellar, autonomic, urinary, and/or pyramidal dysfunction. Urinary and erectile dysfunction (ED) symptoms are prominent early features in men with MSA. Autonomic failure, considered until recently to be the ca...
journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901014
更新日期:2003-08-01 00:00:00
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pub_type: 杂志文章
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更新日期:2010-09-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3901341
更新日期:2005-09-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
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更新日期:2005-05-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
doi:10.1038/sj.ijir.3900856
更新日期:2002-08-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:International journal of impotence research
pub_type: 杂志文章
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更新日期:2000-03-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2010-01-01 00:00:00
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
pub_type: 杂志文章
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更新日期:2004-04-01 00:00:00
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journal_title:International journal of impotence research
pub_type: 临床试验,杂志文章
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