Abstract:
:The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile Function (IIEF)-5 were studied. Participants with ED received three doses (100 mg each) of sildenafil citrate for use over 3 months. Efficacy of sildenafil citrate was assessed using the IIEF-5 and the Global Efficacy Questionnaire (GEQ). Adverse events were recorded by patients in a daily diary. A total of 5477 participants were evaluated, and 75.2% had ED. Age, duration of diabetes and glycosylated hemoglobin (HbA(1)c) >6.5% were independently and significantly associated with the presence and degree of ED. Patients who received pharmacotherapy (N=389) reported significant improvements. The rate of erections as determined by the GEQ was also significantly improved following treatment. ED is a common complication in Chinese men with type 2 diabetes mellitus, and certain risk factors are associated with the presence of ED and severity. Sildenafil citrate is a safe and effective treatment for these patients.
journal_name
Int J Impot Resjournal_title
International journal of impotence researchauthors
Yang G,Pan C,Lu Jdoi
10.1038/ijir.2010.21subject
Has Abstractpub_date
2010-09-01 00:00:00pages
310-7issue
5eissn
0955-9930issn
1476-5489pii
ijir201021journal_volume
22pub_type
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
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journal_title:International journal of impotence research
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pub_type: 杂志文章
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更新日期:2006-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1038/sj.ijir.3901303
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