Gelastic seizures misdiagnosed as gastroesophageal reflux disease.

Abstract:

:Gastroesophageal reflux disease can have variable manifestations including regurgitation, irritability, arching, choking, and apnea. The disorder is also frequently mistaken for seizures (Sandifer syndrome). We report 6 patients in whom the opposite phenomenon occurred: their seizures were mistaken for gastroesophageal reflux disease. Six of 77 patients (6.8%) with gelastic seizures and epilepsy symptomatic of hypothalamic hamartomas were noted to be misdiagnosed with gastroesophageal reflux disease in infancy. As is typical in these patients, gelastic seizures were not diagnosed until months, or often years, later. Delayed diagnosis of hypothalamic hamartomas can lead to a potentially deleterious syndrome involving refractory epilepsy, developmental problems, and precocious puberty. Gelastic seizures should be considered among the conditions that can mimic reflux symptoms.

journal_name

Clin Pediatr (Phila)

journal_title

Clinical pediatrics

authors

Sweetman LL,Ng YT,Kerrigan JF

doi

10.1177/0009922806295400

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

325-8

issue

4

eissn

0009-9228

issn

1938-2707

pii

46/4/325

journal_volume

46

pub_type

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