Different serum concentrations of steady-state valproic acid in two sustained-release formulations.

abstract：:Thirty-seven patients (35 men and two women) with obstructive sleep apnea-hypopnea syndrome (OSAHS) without any known cardiovascular and lung diseases were examined by Doppler echocardiography. Eight of the 37 (21.6%) patients experienced daytime pulmonary hypertension (PH), and all of them had severe OSAHS with an ap...

journal_title：Psychiatry and clinical neurosciences

authors： Yamakawa H,Shiomi T,Sasanabe R,Hasegawa R,Ootake K,Banno K,Wakayama H,Katada M,Kobayashi T

更新日期：2002-06-01 00:00:00

abstract：AIM:Recent cognitive neuroscience research shows that noninvasive brain stimulation can modify a wide range of behaviors in healthy people. Such regulation effects on human behaviors provide new insights into the neurobiology of cognitive processes and establish causal brain-behavior relations. Here, we aimed to examin...

journal_title：Psychiatry and clinical neurosciences

authors： Khaleghi A,Pirzad Jahromi G,Zarafshan H,Mostafavi SA,Mohammadi MR

更新日期：2020-09-01 00:00:00

abstract：:A 65-year-old woman with hypertension developed slowly progressive memory disturbance and disorientation. She was diagnosed as having Alzheimer-type dementia according to clinical criteria. Later her cognitive deterioration was noted to fluctuate in parallel to her blood pressure. Magnetic resonance angiography and si...

journal_title：Psychiatry and clinical neurosciences

authors： Ishibashi K,Tanaka K,Nakabayashi T,Nakamura M,Uchiyama M,Okawa M

更新日期：1998-02-01 00:00:00

abstract：AIM:To evaluate the severity of depression by measuring alterations in prefrontal cortical activity associated with mood disorders, as assessed on near-infrared spectroscopy. METHODS:Ten of 27 subjects hospitalized for late-life depression from May 2006 to June 2007, were examined. In these 10 subjects changes in hemo...

journal_title：Psychiatry and clinical neurosciences

authors： Onishi Y,Kikuchi S,Watanabe E,Kato S

更新日期：2008-04-01 00:00:00

abstract：AIM:This paper describes a 1-year follow-up of post-traumatic stress disorder (PTSD) symptomatology and depression in an elderly minority population who experienced Typhoon Morakot in Taiwan. METHODS:The PTSD Symptom Scale--Interview and the 10-item short form Center for Epidemiological Studies Depression Scale were u...

journal_title：Psychiatry and clinical neurosciences

authors： Chen YL,Hsu WY,Lai CS,Tang TC,Wang PW,Yeh YC,Huang MF,Yen CF,Chen CS

更新日期：2015-01-01 00:00:00

abstract：AIM:Psychiatric disorders are easily underestimated and under-recognized by physicians. The aim of the present study was to investigate the change in accuracy of recognizing psychiatric symptoms. METHODS:Consecutive 5-year consultation-liaison data were collected and patients with one of the five common psychiatric di...

journal_title：Psychiatry and clinical neurosciences

authors： Su JA,Tsai CS,Hung TH,Chou SY

更新日期：2011-12-01 00:00:00

abstract：:Most acute psychotic episodes are regarded as indicators of schizophrenia. We developed an algorithm for the treatment of such episodes. In Japan, psychiatrists tend to prescribe two or more neuroleptics at once, but it is thought that using a single neuroleptic is better, and the algorithm we report is based on this ...

journal_title：Psychiatry and clinical neurosciences

authors： Hayashida M,Nakane Y

更新日期：1999-10-01 00:00:00

abstract：:The main World Health Organization (WHO) activities of the Tokyo Center are as follows: (1) It performed the research project entitled 'A Bio-Psycho-Social Study on Children with Emotional and Behavioral Problems' in cooperation with the Beijing and Seoul Centers from 1985 to 1987. These results suggested that the dev...

journal_title：Psychiatry and clinical neurosciences

authors： Matsushima E,Kojima T,Obayashi S,Ohta K,Ando K,Toru M,Shimazono Y,Takebayashi H,Takahashi S,Xia ML,Ohkura T,Yoshino M,Okubo Y,Matsuura M,Ando H

更新日期：1998-12-01 00:00:00

abstract：:Nuclear polyadenylate polymerase from I activity in the brains of seizure-prone EL mice was significantly higher than in seizure-non-susceptible progenitor ddY mice. This finding may be essential in acquiring susceptibility to seizures, since there was no significant difference between EL(S) mice and those that did no...

journal_title：Psychiatry and clinical neurosciences

authors： Kioka T,Yamagami S,Mui K,Onishi H

更新日期：1997-06-01 00:00:00

abstract：:The uses of lorazepam and electroconvulsive therapy (ECT) have been proven to be effective in treating catatonia. In the present study a modified treatment strategy (i.e. lorazepam i.m. injection or diazepam infused i.v. if lorazepam failed, not with ECT) was proposed to rapidly relieve catatonic signs in patients wit...

journal_title：Psychiatry and clinical neurosciences

authors： Huang TL

更新日期：2005-02-01 00:00:00

abstract：:Major depressive disorder (MDD) with racing/crowded thoughts is understudied. Kraepelin classified 'depression with flight of ideas' in the mixed states of his manic-depressive insanity. The aim of the study was to test whether MDD with racing/crowded thoughts was close to bipolar disorders. Consecutive 379 bipolar-II...

journal_title：Psychiatry and clinical neurosciences

authors： Benazzi F

更新日期：2005-10-01 00:00:00

abstract：:The outcome of first-admission schizophrenic patients at Jichi Medical School Hospital was investigated to identify outcome predictors of schizophrenia among the symptoms at the time of the first hospitalization. The subjects were 62 schizophrenic patients, 29 females and 33 males, consecutively discharged from the De...

journal_title：Psychiatry and clinical neurosciences

authors： Kobayashi T,Kato S

更新日期：2004-10-01 00:00:00

abstract：:This study investigated the relationship between napping and night-time sleep patterns in junior high and high school students. A questionnaire concerning sleep-related lifestyle was given to about 10,000 junior high and high school students. Approximately 50% of the junior high and high school students take at least ...

journal_title：Psychiatry and clinical neurosciences

authors： Fukuda K,Ishihara K

更新日期：2002-06-01 00:00:00

abstract：AIM:The purpose of this study was to examine the following hypothesis: (i) Self-esteem and aggressiveness, adverse childhood experiences (ACE), and a depressive tendency interact with each other. (ii) The subjects show a strong depressive tendency, and each of the other factors exerts a main effect on, and interacts wi...

journal_title：Psychiatry and clinical neurosciences

authors： Matsuura N,Hashimoto T,Toichi M

更新日期：2009-08-01 00:00:00

abstract：:To study course and outcome of Bipolar II disorder, 217 major depressive episode (MDE) patients were interviewed with Structured Clinical Interview for DSM-IV. Patients with more than three MDE and patients with fewer MDE were compared. Patients with more than three MDE were 77.8%. Comparisons, controlled for confound...

journal_title：Psychiatry and clinical neurosciences

authors： Benazzi F

更新日期：2001-02-01 00:00:00

abstract：AIMS:Suicide is a leading cause of death among Japanese college and university students. Gatekeeper-training programs have been shown to improve detection and referral of individuals who are at risk of suicide by training non-mental-health professional persons. However, no studies have investigated the effectiveness of...

journal_title：Psychiatry and clinical neurosciences

authors： Hashimoto N,Suzuki Y,Kato TA,Fujisawa D,Sato R,Aoyama-Uehara K,Fukasawa M,Asakura S,Kusumi I,Otsuka K

更新日期：2016-01-01 00:00:00

abstract：:We have introduced behavior therapy as standard in-patient treatment for anorexia nervosa and have modified the treatment program. At first, we used Fukamachi's activity restriction therapy (FT), followed by Token economy therapy (TET), which combined token economy with FT. Finally, we have developed Kyoto Prefectural...

journal_title：Psychiatry and clinical neurosciences

authors： Okamoto A,Yamashita T,Nagoshi Y,Masui Y,Wada Y,Kashima A,Arii I,Nakamura M,Fukui K

更新日期：2002-10-01 00:00:00

abstract：:Most women experience sleep changes across the menstrual cycle. We applied the ultra-short sleep-wake schedule to healthy females to compare their 24-h sleep propensity rhythms in the follicular and luteal phases. The daytime (09.00-16.30 h) subjective sleepiness and the number of slow wave sleep-containing nap trials...

journal_title：Psychiatry and clinical neurosciences

authors： Shibui K,Uchiyama M,Okawa M,Kudo Y,Kim K,Kamei Y,Hayakawa T,Akamatsu T,Ohta K,Ishibashi K

更新日期：1999-04-01 00:00:00

abstract：:Among 448 patients with obstructive sleep apnea-hypopnea syndrome (OSAHS), 40 patients (8.9%) had been involved in one or more automobile accidents during the preceding 5 years. The main cause of these accidents was falling asleep while driving. Excessive sleepiness during driving was associated with an Epworth sleepi...

journal_title：Psychiatry and clinical neurosciences

authors： Shiomi T,Arita AT,Sasanabe R,Banno K,Yamakawa H,Hasegawa R,Ozeki K,Okada M,Ito A

更新日期：2002-06-01 00:00:00

abstract：AIMS:This 12-week open-label study was designed to investigate the pharmacokinetics and efficacy of a direct switch from a conventional depot to long-acting injectable risperidone in patients with schizophrenia and schizoaffective disorder. METHODS:Men or women from 18 to 65 years old with a diagnosis of schizophrenia...

journal_title：Psychiatry and clinical neurosciences

authors： Lai YC,Huang MC,Chen CH,Tsai CJ,Pan CH,Chiu CC

更新日期：2009-08-01 00:00:00

abstract：:There are many reports of adolescents with periodic episodes, each followed by complete remission within 2 weeks; however, the nosology and long-term prognosis of such cases have not been elucidated. A prospective follow-up study on 11 cases (nine girls and two boys) who met predetermined criteria is reported. The fir...

journal_title：Psychiatry and clinical neurosciences

authors： Abe K,Ohta M

更新日期：1998-12-01 00:00:00

abstract：AIMS:Antisaccadic eye movements, requiring inhibition of a saccade toward a briefly appearing peripheral target, are known to be impaired in schizophrenia. Previous neuroimaging studies have indicated that patients with schizophrenia show diminished activations in the frontal cortex and basal ganglia. These studies use...

journal_title：Psychiatry and clinical neurosciences

authors： Fukumoto-Motoshita M,Matsuura M,Ohkubo T,Ohkubo H,Kanaka N,Matsushima E,Taira M,Kojima T,Matsuda T

更新日期：2009-04-01 00:00:00

abstract：AIM:The orexigenic hormone, ghrelin, is linked to learning and memory in animal studies. No previous study has investigated whether cognition is related to ghrelin in the non-demented elderly. METHODS:Thirty-five older adults underwent neuropsychological testing and fasting blood draw with subsequent serum ghrelin qua...

journal_title：Psychiatry and clinical neurosciences

authors： Spitznagel MB,Benitez A,Updegraff J,Potter V,Alexander T,Glickman E,Gunstad J

更新日期：2010-12-01 00:00:00

abstract：AIM:Several lines of evidence suggest that major depressive disorder is associated with an inflammatory status. Tumor necrosis factor-alpha has been investigated as a potential molecular target in mood disorders. Tumor necrosis factor-alpha exerts its activity through binding to specific cell membrane receptors named a...

journal_title：Psychiatry and clinical neurosciences

authors： Grassi-Oliveira R,Brietzke E,Pezzi JC,Lopes RP,Teixeira AL,Bauer ME

更新日期：2009-04-01 00:00:00

abstract：AIM:Glial fibrillary acidic protein (GFAP), the intermediate filament protein expressed in astrocytes, plays a key role in many aspects of brain function through communication with neurons or blood vessels. A common single nucleotide polymorphism (SNP), GFAP -250 C/A (rs2070935), is associated with the transcriptional ...

journal_title：Psychiatry and clinical neurosciences

authors： Takahashi Y,Takeuchi H,Sakai M,Yu Z,Kikuchi Y,Ito F,Matsuoka H,Tanabe O,Yasuda J,Taki Y,Kawashima R,Tomita H

更新日期：2020-01-01 00:00:00

abstract：AIMS:The purpose of the present study was to investigate the relationship between delusional thoughts (delusional ideation or misidentification) and frontal lobe function using the Japanese version of the Frontal Assessment Battery (FAB) bedside screening neuropsychological test in early stage Alzheimer's disease (AD) ...

journal_title：Psychiatry and clinical neurosciences

authors： Nagata T,Ishii K,Ito T,Aoki K,Ehara Y,Kada H,Furukawa H,Tsumura M,Shinagawa S,Kasahara H,Nakayama K

更新日期：2009-08-01 00:00:00

abstract：:Issues related to recovery of quality of life (QoL) in depressive outpatients have been raised. This descriptive correlation study investigated QoL in depressive outpatients in Taiwan. A total of 181 depressive outpatients participated in the study. Their QoL levels were measured using the Taiwanese version of the Sho...

journal_title：Psychiatry and clinical neurosciences

authors： Sung SC,Yeh MY

更新日期：2007-12-01 00:00:00

abstract：:Serial magnetic resonance (MR) images were obtained for 18 months in the follow-up of a patient with delayed encephalopathy after acute carbon monoxide (CO) poisoning. The characteristic findings on T2-weighted MR images (T2WI) were high intensity in the bilateral periventricular white matter and pallidal regions, and...

journal_title：Psychiatry and clinical neurosciences

authors： Inagaki T,Ishino H,Seno H,Umegae N,Aoyama T

更新日期：1997-12-01 00:00:00

abstract：:The purpose of the present paper was to investigate the role and attitude of people who accompanied geriatric patients to an outpatient psychiatric clinic. The study was conducted at a large university hospital in Taiwan. Participants included 108 patients aged 65 years and older who were seen for their initial psychi...

journal_title：Psychiatry and clinical neurosciences

authors： Chen CY,Chen YJ,Juang YY,Liu CY,Hung CI

更新日期：2004-06-01 00:00:00

abstract：AIM:Auditory mismatch negativity (MMN) and its magnetoencephalographic (MEG) counterpart (MMNm) are an established biological index in schizophrenia research. MMN in response to duration and frequency deviants may have differential relevance to the pathophysiology and clinical stages of schizophrenia. MEG has advantage...

journal_title：Psychiatry and clinical neurosciences

authors： Suga M,Nishimura Y,Kawakubo Y,Yumoto M,Kasai K

更新日期：2016-07-01 00:00:00