Reducing healthy worker survivor bias by restricting date of hire in a cohort study of Vermont granite workers.

Abstract:

OBJECTIVE:To explore the healthy worker survivor effect (HWSE) in a study of Vermont granite workers by distinguishing "prevalent" from "incident" hires based on date of hire before or after the start of follow-up. METHODS:Records of workers between 1950 and 1982 were obtained from a medical surveillance programme. Proportional hazards models were used to model the association between silica exposure and lung cancer mortality, with penalised splines used to smooth the exposure-response relationship. A sensitivity analysis compared results between the original cohort and subcohorts defined by restricting date of hire to include varying proportions of prevalent hires. RESULTS:Restricting to incident hires reduced the 213 cases by 74% and decreased the exposure range. The maximum mortality rate ratio (MRR) was close to twofold in all subcohorts. However, the exposure at which the maximum MRR was achieved decreased from 4.0 to 0.6 mg-year/m3 as the proportion of prevalent hires decreased from 50% in the original cohort to 0% in the subcohort of incident hires. CONCLUSION:Despite loss in power and restricted exposure range, decreasing the relative proportion of prevalent to incident hires reduced HWSE bias, resulting in stronger evidence for a dose-response between silica exposure and lung cancer mortality.

journal_name

Occup Environ Med

authors

Applebaum KM,Malloy EJ,Eisen EA

doi

10.1136/oem.2006.031369

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

681-7

issue

10

eissn

1351-0711

issn

1470-7926

pii

oem.2006.031369

journal_volume

64

pub_type

杂志文章
  • Occupational exposure assessment in case-control studies: opportunities for improvement.

    abstract::Community based case-control studies are an efficient means to study disease aetiologies, and may be the only practical means to investigate rare diseases. However, exposure assessment remains problematic. We review the literature on the validity and reliability of common case-control exposure assessment methods: occu...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章,评审

    doi:10.1136/oem.59.9.575

    authors: Teschke K,Olshan AF,Daniels JL,De Roos AJ,Parks CG,Schulz M,Vaughan TL

    更新日期:2002-09-01 00:00:00

  • Air pollution and childhood leukaemia: a nationwide case-control study in Italy.

    abstract:OBJECTIVES:Leukaemia is the most common cancer in children, but its aetiology is still poorly understood. We tested the hypothesis that traffic-related air pollution is associated with paediatric leukaemia because of chronic exposure to several potential carcinogens. METHODS:The Italian SETIL study (Study on the aetio...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2013-101604

    authors: Badaloni C,Ranucci A,Cesaroni G,Zanini G,Vienneau D,Al-Aidrous F,De Hoogh K,Magnani C,Forastiere F,SETIL Study Group.

    更新日期:2013-12-01 00:00:00

  • Prevention of work related eye injuries: long term assessment of the effectiveness of a multicomponent intervention among metal workers.

    abstract:BACKGROUND:Systematic assessments of the effectiveness of interventions to prevent work related eye injuries are needed. AIM:To investigate the long term effectiveness of a multicomponent prevention campaign. METHODS:The campaign (conducted in collaboration with the local Employers' Association and Trade Unions) targ...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.2004.019570

    authors: Mancini G,Baldasseroni A,Laffi G,Curti S,Mattioli S,Violante FS

    更新日期:2005-12-01 00:00:00

  • Mortality in uranium miners in west Bohemia: a long-term cohort study.

    abstract::A cohort of 4320 uranium miners in West Bohemia who started work at the mines during 1948 to 1959 and worked there for at least four years were followed up to the end of 1990 to determine cause specific mortality risks in relation to exposures in the mines. The miners had experienced high radon exposures, on average 2...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.51.5.308

    authors: Tomásek L,Swerdlow AJ,Darby SC,Placek V,Kunz E

    更新日期:1994-05-01 00:00:00

  • The effect of individual counselling and education on work ability and disability pension: a prospective intervention study in the construction industry.

    abstract:OBJECTIVES:To investigate the effectiveness of a counselling and education programme on work ability and work disability pension for employees in the construction industry. METHODS:Employees with a high disability risk of 38% or more in the following four years were included. Employees in the intervention group were e...

    journal_title:Occupational and environmental medicine

    pub_type: 临床试验,杂志文章

    doi:10.1136/oem.2006.029678

    authors: de Boer AG,Burdorf A,van Duivenbooden C,Frings-Dresen MH

    更新日期:2007-12-01 00:00:00

  • Occupational standing and change in the Ankle-Brachial Index: the Jackson Heart Study.

    abstract:BACKGROUND:A growing interest in reducing occupational sitting has resulted in public health efforts to encourage intermittent standing in workplaces. However, concerns have been raised that standing for prolonged periods may expose individuals to new health hazards, including lower limb atherosclerosis. These concerns...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2020-106905

    authors: Friel CP,Duran AT,Abdalla M,Unkart JT,Bellettiere J,Sims M,Correa A,Shimbo D,Diaz KM

    更新日期:2020-11-03 00:00:00

  • Mortality among aircraft manufacturing workers.

    abstract:OBJECTIVES:To evaluate the risk of cancer and other diseases among workers engaged in aircraft manufacturing and potentially exposed to compounds containing chromate, trichloroethylene (TCE), perchloroethylene (PCE), and mixed solvents. METHODS:A retrospective cohort mortality study was conducted of workers employed f...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.56.9.581

    authors: Boice JD Jr,Marano DE,Fryzek JP,Sadler CJ,McLaughlin JK

    更新日期:1999-09-01 00:00:00

  • Shift work, job strain and changes in the body mass index among women: a prospective study.

    abstract:OBJECTIVES:The effects of job strain and shift work on weight gain have not been studied jointly. Cross-sectional and longitudinal studies on shift work and weight gain have reported different results. This study examines potential effect modification by job strain on the link between shift work and weight gain, and co...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2016-103747

    authors: Fujishiro K,Lividoti Hibert E,Schernhammer E,Rich-Edwards JW

    更新日期:2017-06-01 00:00:00

  • Immunological markers among workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin.

    abstract:OBJECTIVES:To examine the association of immune cell number and function with occupational exposure to substances contaminated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). METHODS:A cross sectional medical survey. The exposed participants were employed at two chemical plants between 1951 and 1972 in the manufactur...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.55.11.742

    authors: Halperin W,Vogt R,Sweeney MH,Shopp G,Fingerhut M,Petersen M

    更新日期:1998-11-01 00:00:00

  • Risk of cancer among paper recycling workers.

    abstract:OBJECTIVES:Studies in traditional paper mills have indicated an excess cancer risk, and mutagenic compounds have been identified in the industry. No studies have reported on risk of cancer in paper recycling. Therefore the cancer incidence in Danish paper recycling mills was investigated. METHODS:5377 employees in fiv...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.54.10.729

    authors: Rix BA,Villadsen E,Engholm G,Lynge E

    更新日期:1997-10-01 00:00:00

  • Shift work and diabetes mellitus: a meta-analysis of observational studies.

    abstract:BACKGROUND:Observational studies suggest that shift work may be associated with diabetes mellitus (DM). However, the results are inconsistent. No systematic reviews have applied quantitative techniques to compute summary risk estimates. OBJECTIVES:To conduct a meta-analysis of observational studies assessing the assoc...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1136/oemed-2014-102150

    authors: Gan Y,Yang C,Tong X,Sun H,Cong Y,Yin X,Li L,Cao S,Dong X,Gong Y,Shi O,Deng J,Bi H,Lu Z

    更新日期:2015-01-01 00:00:00

  • Allergic airway disease in Italian bakers and pastry makers.

    abstract::A survey was carried out on respiratory symptoms and skin prick test response to common allergens (atopy), storage mites, and occupational allergens among 226 bakers and pastry makers from 105 small businesses in northern Italy. Atopy was present in 54 workers (23.4%); 40 workers (17.7%) were skin positive to at least...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.51.8.548

    authors: De Zotti R,Larese F,Bovenzi M,Negro C,Molinari S

    更新日期:1994-08-01 00:00:00

  • Exposure to polycyclic aromatic hydrocarbons in coal liquefaction workers: impact of a workwear policy on excretion of urinary 1-hydroxypyrene.

    abstract:OBJECTIVE:This study was undertaken to assess whether contaminated personal clothing worn beneath a coverall (normal workwear) is a source of potentially significant dermal exposure to polycyclic aromatic hydrocarbons (PAHs) in coal liquefaction workers. METHODS:An intervention study was conducted over a two week peri...

    journal_title:Occupational and environmental medicine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1136/oem.52.9.600

    authors: Quinlan R,Kowalczyk G,Gardiner K,Calvert I

    更新日期:1995-09-01 00:00:00

  • The role of cumulative physical work load in lumbar spine disease: risk factors for lumbar osteochondrosis and spondylosis associated with chronic complaints.

    abstract:OBJECTIVES:To investigate the relation with a case-control study between symptomatic osteochondrosis or spondylosis of the lumbar spine and cumulative occupational exposure to lifting or carrying and to working postures with extreme forward bending. METHODS:From two practices and four clinics were recruited 229 male p...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.58.11.735

    authors: Seidler A,Bolm-Audorff U,Heiskel H,Henkel N,Roth-Küver B,Kaiser U,Bickeböller R,Willingstorfer WJ,Beck W,Elsner G

    更新日期:2001-11-01 00:00:00

  • Occupational radiation exposure and excess additive risk of cataract incidence in a cohort of US radiologic technologists.

    abstract:OBJECTIVES:Previous analyses of cataract in radiation-exposed populations have assessed relative risk; radiogenic excess additive risk (EAR), arguably of more public health importance, has not been estimated. Previous analysis of a large prospective cohort of US radiologic technologists (USRT) quantified excess relativ...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2019-105902

    authors: Little MP,Cahoon EK,Kitahara CM,Simon SL,Hamada N,Linet MS

    更新日期:2020-01-01 00:00:00

  • COPD, airflow limitation and chronic bronchitis in farmers: a systematic review and meta-analysis.

    abstract:INTRODUCTION:The current definition of chronic obstructive pulmonary disease (COPD) associates persistent airflow limitation and chronic respiratory symptoms. Agricultural work has been associated with an increased risk of developing COPD, but the prevalence and definition of the disease vary greatly between studies. T...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章,meta分析

    doi:10.1136/oemed-2018-105310

    authors: Guillien A,Soumagne T,Dalphin JC,Degano B

    更新日期:2019-01-01 00:00:00

  • Risk factors for chronic mucus hypersecretion in individuals with and without COPD: influence of smoking and job exposure on CMH.

    abstract:BACKGROUND:Chronic mucus hypersecretion (CMH) is highly prevalent in smokers and associated with an accelerated lung function decline and chronic obstructive pulmonary disease (COPD). Several risk factors contribute to CMH and to COPD. It is, however, unknown if risk factors for CMH are similar in persons with and with...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2013-101654

    authors: Dijkstra AE,de Jong K,Boezen HM,Kromhout H,Vermeulen R,Groen HJ,Postma DS,Vonk JM

    更新日期:2014-05-01 00:00:00

  • Demographic variation in fit note receipt and long-term conditions in south London.

    abstract:OBJECTIVES:Introduced in the UK in 2010, the fit note was designed to address the problem of long-term sickness absence. We explored (1) associations between demographic variables and fit note receipt, 'maybe fit' use and long-term conditions, (2) whether individuals with long-term conditions receive more fit notes and...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2019-106035

    authors: Dorrington S,Carr E,Stevelink SAM,Dregan A,Whitney D,Durbaba S,Ashworth M,Mykletun A,Broadbent M,Madan I,Hatch S,Hotopf M

    更新日期:2020-06-01 00:00:00

  • Shiftwork and mortality from ischaemic heart disease.

    abstract:OBJECTIVES:To investigate the relation between shift work and death from ischaemic heart disease (IHD). METHODS:A nested case-control approach was used. The cohort comprised male manual workers who joined an industrial company aged 50 years or under between 1 January 1950 and 31 December 1992 and worked there for at l...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.53.6.367

    authors: McNamee R,Binks K,Jones S,Faulkner D,Slovak A,Cherry NM

    更新日期:1996-06-01 00:00:00

  • Association of petrochemical exposure with spontaneous abortion.

    abstract:OBJECTIVES:To assess the association between petrochemical exposure and spontaneous abortion, a retrospective epidemiological study in a large petrochemical complex in Beijing, China was conducted. METHODS:Plant employment records identified 3105 women who were married, were 20-44 years of age, and had never smoked. O...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.55.1.31

    authors: Xu X,Cho SI,Sammel M,You L,Cui S,Huang Y,Ma G,Padungtod C,Pothier L,Niu T,Christiani D,Smith T,Ryan L,Wang L

    更新日期:1998-01-01 00:00:00

  • Reducing sedentary behaviour to decrease chronic low back pain: the stand back randomised trial.

    abstract:OBJECTIVE:The Stand Back study evaluated the feasibility and effects of a multicomponent intervention targeting reduced prolonged sitting and pain self-management in desk workers with chronic low back pain (LBP). METHODS:This randomised controlled trial recruited 27 individuals with chronic LBP, Oswestry Disability In...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章,随机对照试验

    doi:10.1136/oemed-2017-104732

    authors: Barone Gibbs B,Hergenroeder AL,Perdomo SJ,Kowalsky RJ,Delitto A,Jakicic JM

    更新日期:2018-05-01 00:00:00

  • Daily concentrations of air pollution and plasma fibrinogen in London.

    abstract:OBJECTIVES:The reason for the association between air pollution and risk of cardiovascular diseases is unknown. The hypothesis was examined that daily concentrations of air pollution are associated with daily concentrations of fibrinogen, a risk factor for cardiovascular disease. METHODS:Data on concentrations of plas...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.57.12.818

    authors: Pekkanen J,Brunner EJ,Anderson HR,Tiittanen P,Atkinson RW

    更新日期:2000-12-01 00:00:00

  • Airborne occupational exposures and inflammatory biomarkers in the Lifelines cohort study.

    abstract:INTRODUCTION:Inflammatory biomarkers are associated with negative health outcomes. In this study, we investigated the associations between airborne occupational exposures and levels and changes in inflammatory biomarkers. METHODS:We included 79 604 adults at baseline from the Lifelines cohort of which 48 403 (60.8%) s...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2020-106493

    authors: Faruque MO,Vonk JM,Bültmann U,Boezen HM

    更新日期:2020-08-07 00:00:00

  • Parental occupation at periconception: findings from the United Kingdom Childhood Cancer Study.

    abstract:AIMS:To study the risk of childhood cancer in relation to parental occupation and related exposures. METHODS:Self reported occupational data from mothers and fathers of 3838 children with cancer and 7629 control children were analysed. Odds ratios were calculated for 31 "occupational groups" by parent, diagnostic grou...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.60.12.901

    authors: McKinney PA,Fear NT,Stockton D,UK Childhood Cancer Study Investigators.

    更新日期:2003-12-01 00:00:00

  • Multiple sclerosis in nurse anaesthetists.

    abstract:BACKGROUND:Volatile anaesthetics are chemically related to organic solvents used in industry. Exposure to industrial solvents may increase the incidence of multiple sclerosis (MS). AIM:To examine the risk among nurse anaesthetists of contracting MS. METHODS:Nurses with MS were identified by an appeal in the monthly m...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.60.1.66

    authors: Flodin U,Landtblom AM,Axelson O

    更新日期:2003-01-01 00:00:00

  • Prevalence of chronic fatigue syndrome-like caseness in the working population: results from the Maastricht cohort study.

    abstract:AIM:To determine the prevalence of chronic fatigue syndrome (CFS)-like caseness in the working population. METHODS:Using data from the prospective Maastricht Cohort Study on Fatigue at Work, the prevalence and incidence of CFS-like cases (employees meeting research criteria for CFS) were determined among 5499 employee...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.2003.008912

    authors: Huibers MJ,Kant IJ,Swaen GM,Kasl SV

    更新日期:2004-05-01 00:00:00

  • Respiratory symptoms and diseases among workers in the soft tissue producing industry.

    abstract:AIMS:To correlate the prevalence of respiratory tract symptoms and diseases with dust and fibre exposure in the soft tissue industry in Germany. METHODS:Ambient monitoring was performed for inhalable, respirable dust and fibres in seven soft tissue producing factories. In 441 workers (72 controls, 90 moderate, 279 hig...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.59.12.830

    authors: Kraus T,Pfahlberg A,Gefeller O,Raithel HJ

    更新日期:2002-12-01 00:00:00

  • Subjective symptoms, sleeping problems, and cognitive performance in subjects living near mobile phone base stations.

    abstract:BACKGROUND:The erection of mobile telephone base stations in inhabited areas has raised concerns about possible health effects caused by emitted microwaves. METHODS:In a cross-sectional study of randomly selected inhabitants living in urban and rural areas for more than one year near to 10 selected base stations, 365 ...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.2005.020784

    authors: Hutter HP,Moshammer H,Wallner P,Kundi M

    更新日期:2006-05-01 00:00:00

  • Blood lead and erythrocyte protoporphyrin levels in association with smoking and personal hygienic behaviour among lead exposed workers.

    abstract:AIMS:To investigate the effects of smoking and personal hygienic behaviour on blood lead (BPb) and free erythrocyte protoporphyrin levels (FEP) in lead exposed workers. METHODS:Subjects were 105 lead exposed male workers in a battery recycling plant during the years 2000-03. BPb and FEP were measured as part of the on...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oem.2004.019513

    authors: Karita K,Nakao M,Ohwaki K,Yamanouchi Y,Nishikitani M,Nomura K,Sato M,Yano E

    更新日期:2005-05-01 00:00:00

  • Night shift work and incidence of diabetes in the Danish Nurse Cohort.

    abstract:OBJECTIVES:Night shift work has been associated with poor sleep, weight gain, metabolic syndrome, which are recognised risk factor for diabetes. However, only a few studies have examined the effect of shift work on diabetes risk. Here, we study the association between shift work and incidence of diabetes in Danish nurs...

    journal_title:Occupational and environmental medicine

    pub_type: 杂志文章

    doi:10.1136/oemed-2015-103342

    authors: Hansen AB,Stayner L,Hansen J,Andersen ZJ

    更新日期:2016-04-01 00:00:00