Abstract:
:Pairs of forward and reverse primers and TaqMan probes specific to each of 15 human sulfotransferases were prepared. The mRNA expression level of each target enzyme was analyzed in total RNA from single and pooled specimens of various human tissues (adrenal gland, bone marrow, brain, colon, heart, kidney, liver, lung, pancreas, peripheral leukocytes, placenta, prostate, salivary gland, skeletal muscle, small intestine, spinal cord, spleen, stomach, testis, thymus, thyroid gland, trachea, and uterus) by real-time reverse transcription PCR using an ABI PRISM 7700 Sequence Detection System. The mRNA expression profiles of the sulfotransferases in these 23 different human tissues were used to identify the tissues exhibiting high transcriptional activity for these enzymes. These results provide valuable information for studies concerning the human carbohydrate sulfotransferase and tyrosylprotein sulfotransferase genes in various tissues.
journal_name
Biol Pharm Bulljournal_title
Biological & pharmaceutical bulletinauthors
Nishimura M,Naito Sdoi
10.1248/bpb.30.821subject
Has Abstractpub_date
2007-04-01 00:00:00pages
821-5issue
4eissn
0918-6158issn
1347-5215pii
JST.JSTAGE/bpb/30.821journal_volume
30pub_type
杂志文章abstract::The in vitro antimalarial activity against human malaria parasite (Plasmodium falciparum, FCR-3 strain) was examined using 59 triterpenoids obtained during studies on the triterpenic constituents of Cimicifuga spp. The 50% effective concentration values (EC50) of 25 active triterpenoids were 1.0-3.0 microM, and 19 of ...
journal_title:Biological & pharmaceutical bulletin
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更新日期:2005-09-01 00:00:00
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更新日期:2005-07-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
pub_type: 杂志文章
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更新日期:2004-07-01 00:00:00
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更新日期:2008-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:1994-02-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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journal_title:Biological & pharmaceutical bulletin
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更新日期:2015-01-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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journal_title:Biological & pharmaceutical bulletin
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abstract::Immediate early genes (IEG) are rapidly but transiently induced directly by intracellular signaling cascades to alter patterns of gene expression. It has been proposed that histone modifications could be the key to the quick alteration of chromatin structure, as this spread occurs too rapidly to be the consequence of ...
journal_title:Biological & pharmaceutical bulletin
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abstract::Using a plaque reduction assay, treatment of human influenza A viruses with the fruit-juice concentrate of Japanese plum (Prunus mume SIEB. et ZUCC) showed strong in vitro anti-influenza activity against human influenza A viruses before viral adsorption, but not after viral adsorption, with 50% inhibitory concentratio...
journal_title:Biological & pharmaceutical bulletin
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更新日期:2008-03-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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更新日期:2013-01-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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journal_title:Biological & pharmaceutical bulletin
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更新日期:2020-01-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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doi:10.1248/bpb.25.872
更新日期:2002-07-01 00:00:00
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journal_title:Biological & pharmaceutical bulletin
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