Abstract:
:The direct Michael addition reaction of cyclohexanone/aliphatic aldehydes with nitroolefins, catalyzed by a novel chiral pyrrolidine-thiourea catalyst 1a, is described. The desired 1,4-adducts were obtained in moderate yields with enantioselectivities up to 99% ee and dr up to 99:1 of the syn product.
journal_name
Chiralityjournal_title
Chiralityauthors
Shen Z,Zhang Y,Jiao C,Li B,Ding J,Zhang Ydoi
10.1002/chir.20382subject
Has Abstractpub_date
2007-05-05 00:00:00pages
307-12issue
4eissn
0899-0042issn
1520-636Xjournal_volume
19pub_type
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