Abstract:
:An asymmetric synthesis of alpha-amino acids with novel beta-branched side chains has been implemented. The syntheses feature a p-toluenesulfinylimine induced chiral Strecker approach and were found to be applicable to the introduction of both aliphatic and aromatic beta-branched sidechains for preparation of previously unknown alpha-amino acids.
journal_name
Bioorg Med Chem Lettjournal_title
Bioorganic & medicinal chemistry lettersauthors
Zhang M,Porte A,Diamantidis G,Sogi K,Kubrak D,Resnick L,Mayer SC,Wang Z,Kreft AF,Harrison BLdoi
10.1016/j.bmcl.2007.02.041subject
Has Abstractpub_date
2007-05-01 00:00:00pages
2401-3issue
9eissn
0960-894Xissn
1464-3405pii
S0960-894X(07)00239-9journal_volume
17pub_type
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