Membranoproliferative glomerulonephritis in a patient with Wilson's disease.

abstract：:Toll-like receptors (TLRs) are a class of receptors of the innate immune system which detect pathogen-associated and danger-associated molecular patterns in order to initiate an inflammatory response. TLR2 and TLR4 downward signaling causes the production of proinflammatory cytokines that can induce insulin resistance...

journal_title：Journal of nephrology

authors： Garibotto G,Carta A,Picciotto D,Viazzi F,Verzola D

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Gut-derived uremic toxins have been associated with adverse outcomes in chronic kidney disease (CKD). Alterations in bowel habits, including constipation, seem to play an additional role in uremic toxicity. The aim of this study is to investigate the association of bowel habits with gut-derived uremic toxins...

journal_title：Journal of nephrology

authors： Pereira NBF,Ramos CI,de Andrade LS,Teixeira RR,Nakao LS,Rodrigues SD,de Lima JD,Dalboni MA,Cuppari L

更新日期：2020-10-01 00:00:00

abstract：:The most common cause of liver disease worldwide is now non-alcoholic fatty liver disease (NAFLD). NAFLD refers to a spectrum of disease ranging from steatosis to non-alcoholic steatohepatitis, causing cirrhosis, and ultimately hepatocellular carcinoma. However, the impact of NAFLD is not limited to the liver. NAFLD h...

journal_title：Journal of nephrology

authors： Kanbay M,Bulbul MC,Copur S,Afsar B,Sag AA,Siriopol D,Kuwabara M,Badarau S,Covic A,Ortiz A

更新日期：2020-05-21 00:00:00

abstract：BACKGROUND:Patients with IgA nephropathy and histological vasculitic/crescentic lesions have a poor prognosis. We performed a retrospective study to assess whether treatment with steroids and immunosuppressants would preserve renal function by healing these lesions and thereby prevent progression to glomerular sclerosi...

journal_title：Journal of nephrology

authors： Harper L,Ferreira MA,Howie AJ,Savage CO,Richards NT,Michael J,Adu D

更新日期：2000-09-01 00:00:00

abstract：:The pathogenesis of calcium-oxalate (CaOx) renal stones is still debated and a number of issues needs to be clarified. In particular, it is difficult to combine the intraluminal physical-chemical imbalance and fixed particle theory with the evidence that CaOx stones actually form and grow on Randall's plaque in the re...

journal_title：Journal of nephrology

authors： Gambaro G,D'Angelo A,Fabris A,Tosetto E,Anglani F,Lupo A

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Different mitogens are involved in the pathogenesis of kidney damage after subtotal nephrectomy. One of them, TGF-beta, controls mesangial cell proliferation and interstitial fibrosclerosis. The transduction of the TGF-beta signal is controlled by intracellular signalling molecules such as Ras G monomeric pr...

journal_title：Journal of nephrology

authors： Bernardini N,Cupisti A,Mattii L,Segnani C,Dolf A,Barsotti M,Barsotti G

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:Post-transplant malignancies are among the most important complications in organ transplantation. Hemangioblastoma (HB) is especially prevalent in the cerebellum. CASE REPORT:A 20-year-old male who first started dialysis therapy, and then underwent kidney transplantation from a living-relative donor. Five...

journal_title：Journal of nephrology

authors： Oztürk S,Soyluk O,Görçin S,Alişir S,Güven D,Türkmen A,Sever MS

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:The effect of interleukin-11 (IL-11) on transforming growth factor-ß (TGF-ß) is controversial and has not been examined in renal diseases. In this study, we (i) characterised the up-regulation of TGF-ß1, phospho-p38 MAPK (p-p38 MAPK) and extracellular matrix during pathogenesis of glomerulonephritis and (ii)...

journal_title：Journal of nephrology

authors： Stangou M,Bhangal G,Lai PC,Smith J,Keith JC Jr,Boyle JJ,Pusey CD,Cook T,Tam FW

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Plasmin has recently been reported to be associated with renal fibrosis in experimental models, but its role in human renal diseases is unclear. METHODS:Fifty-seven patients with IgA nephropathy (IgAN) were evaluated retrospectively. Plasmin in their renal biopsy tissues was assessed by in situ zymography u...

journal_title：Journal of nephrology

authors： Uchida T,Oda T,Takechi H,Matsubara H,Watanabe A,Yamamoto K,Oshima N,Sakurai Y,Kono T,Shimazaki H,Tamai S,Kumagai H

更新日期：2016-02-01 00:00:00

abstract：:Hyperuricosuric calcium urolithiasis is a condition of mixed calcium oxalate stones characterized by hyperuricosuria either in isolation or in conjunction with other risk factors for calcium oxalate stones such as hypercalciuria, hyperoxaluria, and hypocitraturia. There are three proposed physicochemical models of pat...

journal_title：Journal of nephrology

authors： Moe OW,Xu LHR

更新日期：2018-04-01 00:00:00

abstract：:Structural and functional alterations affecting the aging kidney predispose to an increased risk of acute renal failure (ARF) in the elderly. This is a common problem becoming more relevant because of an increase in life expectancy. The epidemiology of ARF in the elderly is far from being well assessed, because of the...

journal_title：Journal of nephrology

authors： Del Giudice A,Aucella F

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In the general population and in hemodialysis patients epicardial adipose tissue (EAT) has been associated with increased mortality and cardiovascular events. Weight loss and lipid lowering therapies reduced EAT in the general population. It is unknown whether sevelamer, a phosphate (Pi) binder that lowers c...

journal_title：Journal of nephrology

authors： Ko SM,Zhang C,Chen Z,D'Marco L,Bellasi A,Stillman AE,Block G,Raggi P

更新日期：2016-10-01 00:00:00

abstract：:Autosomal recessive and autosomal dominant polycystic kidney disease (ADPKD and ARPKD) are 2 major variants of inherited diseases leading to the cystic degeneration of the kidney and other organs. Primary cilia have moved into the focus of research as it is becoming increasingly clear that dysfunction of this special ...

journal_title：Journal of nephrology

authors： Wagner CA

更新日期：2008-01-01 00:00:00

abstract：:Cutaneous periarteritis nodosa (PAN) is a clinical feature characterized by chronic, benign course; its pathogenesis is unknown. In patients submitted to renal transplantation cutaneous PAN is a rare complication. We report a case of cutaneous PAN associated with the reappearance of hepatitis B antigen 16 years after ...

journal_title：Journal of nephrology

authors： Bedani PL,Bergami M,Cavazzini PL,Strumia R,Morelli MC,Stabellini G,Gilli P

更新日期：2001-09-01 00:00:00

abstract：:Osteoporosis and chronic kidney disease (CKD) have both independently important potential impact on bone health. A significant number of patients with CKD stages 3a-5D have been shown to have low bone mineral density (BMD), leading to a strikingly elevated risk of fractures (mainly hip fractures) and higher associated...

journal_title：Journal of nephrology

authors： Bover J,Bailone L,López-Báez V,Benito S,Ciceri P,Galassi A,Cozzolino M

更新日期：2017-10-01 00:00:00

abstract：:Clinical immunology laboratories play an essential role in diagnosis and monitoring of systemic lupus erythematosus (SLE). To obtain the best results in terms of diagnostic performance and clinical usefulness, the following recommendations should be fulfilled: Indirect immunofluorescence on Hep-2 cells remains the met...

journal_title：Journal of nephrology

authors： Sinico RA,Bollini B,Sabadini E,Di Toma L,Radice A

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Left ventricular (LV) geometric patterns have never been evaluated as independent risk factors for renal disease progression (RDP). We investigated the risk factors for RDP in type 2 diabetic nephropathy patients, especially focusing on the effects of LV geometric patterns. METHODS:This was a single-center ...

journal_title：Journal of nephrology

authors： Moon SJ,Bae KS,Park HC,Kim JK,Park JT,Lee JE,Rim SJ,Ha SK

更新日期：2011-01-01 00:00:00

abstract：:Ambulatory blood pressure monitoring (ABPM) has been developed to overcome recognized deficiencies and inaccuracies of classic (office) BP measurements in the diagnosis and management of hypertension (HTN). Although in adults it has become a valuable tool for the diagnosis and ongoing management of HTN, and its use ha...

journal_title：Journal of nephrology

authors： Gavrilovici C,Goldsmith DJ,Reid C,Gubeth-Tatomir P,Covic A

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Malnutrition is common and associated with poor outcomes in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD). Recently, the geriatric nutritional risk index (GNRI) was reported as a novel tool for evaluating nutritional status. However, the association between GNRI and renal outc...

journal_title：Journal of nephrology

authors： Xiong J,Wang M,Wang J,Yang K,Shi Y,Zhang J,Zhang B,Zhang L,Zhao J,Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE).

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Cardiovascular (CV) diseases are the main cause of death in maintenance hemodialysis (MHD) patients. Muscle wasting and physical function decline are common in MHD patients, and significantly impair their quality of life. These can result from abnormalities in cardiac function, which can be further worsened ...

journal_title：Journal of nephrology

authors： Jeong JH,Wu PT,Kistler BM,Fitschen PJ,Biruete AG,Phillips SA,Ali MM,Fernhall B,Wilund KR

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To investigate the pregnancy outcomes for patients with stage 3-4 chronic kidney disease (CKD) and the effects of pregnancy on kidney function. METHODS:Clinical data of pregnant women with CKD in the Peking University First Hospital between January 1st 2005 and October 1st 2016 were retrospectively analysed....

journal_title：Journal of nephrology

authors： He Y,Liu J,Cai Q,Lv J,Yu F,Chen Q,Zhao M

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Chronotropic incompetence (CI) is an independent predictor of cardiovascular events and overall mortality. The prevalence and significance of CI in renal transplant patient has not been examined. METHODS:38 non-heart failure renal transplant recipients were recruited for a transthoracic echocardiogram and t...

journal_title：Journal of nephrology

authors： Ma MK,Zuo ML,Yap DY,Mok MM,Kwan LP,Chan GC,Siu DC,Chan TM

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:This study was undertaken to examine whether there is an association between parity and age at first birth and risk of death from chronic renal failure (CRF). STUDY DESIGN:Prospective cohort study. SETTING AND PARTICIPANTS:The study cohort consisted of 1 292 462 women who had a first and singleton childbir...

journal_title：Journal of nephrology

authors： Kuo CC,Lee CT,Chen CC,Tsai SS,Yang CY

更新日期：2013-03-01 00:00:00

abstract：:Inherited distal renal tubular acidosis (dRTA) is caused by impaired urinary acid excretion resulting in hyperchloremic metabolic acidosis. Although the glomerular filtration rate (GFR) is usually preserved, and hypertension and overt proteinuria are absent, it has to be considered that patients with dRTA also suffer ...

journal_title：Journal of nephrology

authors： Seeger H,Salfeld P,Eisel R,Wagner CA,Mohebbi N

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with increased morbidity and mortality in cardiovascular disease (CVD). Apart from traditional risk factors, chronic inflammation, oxidative stress, malnutrition and endothelial dysfunction are important in CVD development in renal patients. Our aim was to investiga...

journal_title：Journal of nephrology

authors： Annuk M,Soveri I,Zilmer M,Lind L,Hulthe J,Fellström B

更新日期：2005-11-01 00:00:00

abstract：:With increasingly accurate non-invasive tests, the clinician frequently discovers obstruction of the renal arteries by atherosclerosis. The decision to reverse this obstruction is not straightforward, particularly when blood pressure can be easily controlled with medications. Proper management of this problem requires...

journal_title：Journal of nephrology

authors： Middleton JP

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Chronic kidney disease is a risk factor for death in the year following myocardial infarction or coronary angioplasty. Whether the risk is similar after coronary stenting, whether impaired renal function is associated with an increased risk of cardiovascular death or myocardial infarction (MI) after coronary...

journal_title：Journal of nephrology

authors： Charytan DM,Kuntz RE,Chhabra A,Cutlip DE

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:There have been many studies in recent years concerning the role of nitric oxide (NO) in acute renal failure (ARF). In this study, the effects of the inhibition or the induction of NO synthase (NOS) on gentamicin-induced ARF was investigated in isolated perfused rat kidneys. METHODS:Kidneys from male Spragu...

journal_title：Journal of nephrology

authors： Ghaznavi R,Faghihi M,Kadkhodaee M,Shams S,Khastar H

更新日期：2005-09-01 00:00:00

abstract：:Sarcoidosis is a multisystem disorder of unknown etiology, which may occur in all tissues and organs of the body. Clinical presentation may be quite variable and affected by race. The most commonly affected system is the lungs with >95% of patients displaying such involvement. Renal involvement is uncommon (<2%) and m...

journal_title：Journal of nephrology

authors： Carmichael P,O'Donnell JP

更新日期：2003-09-01 00:00:00

abstract：:The pathogenetic role of adiponectin (ADPN) in kidney failure is not yet elucidated, since in vitro and in vivo studies have demonstrated that ADPN exerts both anti-inflammatory and pro-inflammatory effects. Starting from our previous findings demonstrating that HK-2 cells express and secrete ADPN, in this study we in...

journal_title：Journal of nephrology

authors： Perri A,Vizza D,Lupinacci S,Toteda G,De Amicis F,Leone F,Gigliotti P,Lofaro D,La Russa A,Bonofiglio R

更新日期：2016-04-01 00:00:00