Abstract：
INTRODUCTION:Semantic dementia is a progressive, relatively selective disorder affecting the semantic system with involvement of the verbal and non-verbal functions. The clinical picture is well characterised despite the confusion that may be generated by the different ways of classifying it. AIM. To determine the clinical, neurolinguistic, imaging and pathological features of this progressive language disorder. DEVELOPMENT:Evaluation of language reveals above all the existence of semantic paraphasias, disorders affecting the comprehension of isolated words and surface dyslexia. Flow of speech, complex syntactic comprehension and grammar are preserved. Both episodic and autobiographic memory are close to normality. Both the clinical signs and symptoms and imaging studies agree on the fact that the most heavily affected area is the anteroinferomedial region of the temporal lobe on a bilateral scale but with predominance of the left-hand side. Pathologically, in most cases positive intraneuronal ubiquitin inclusions are observed like those described in motor neuron diseases. CONCLUSIONS:Semantic dementia constitutes a diagnosis challenge, mainly from the neuropsychological point of view. Further advances towards reaching a diagnosis would allow us to determine which area is mainly affected and, in the future, to find an effective treatment for this progressive, degenerative disorder.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
O'Neill S,Andreotti M,de Simone Vsubject
Has Abstractpub_date
2006-12-01 00:00:00pages
685-9issue
11eissn
0210-0010issn
1576-6578pii
rn2005763journal_volume
43pub_type
杂志文章,评审abstract：INTRODUCTION:Reduced facial expression or amimia is one of the most typical characteristics of Parkinson's disease (PD). Despite being described in classic texts, its significance, physiopathology and correlation with motor and non-motor symptoms is largely unknown. PATIENTS AND METHODS:We have studied facial bradykin...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2018-01-16 00:00:00
abstract：INTRODUCTION AND OBJECTIVE:Some medical factors related with cardiopulmonary resuscitation (CPR) outcome are known. Moreover, there are other factors, not strictly medical ones, as age, gender, race and socioeconomic status, that influence on decisions of CPR. The aim of this study was to analyse the influence of all t...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-10-01 00:00:00
abstract：:Disorders of gait are a common problem in elderly people. It is estimated that over 15% of people aged over 65 years have disorders of gait. Disorders of balance are also common in old age, with increased risk of falling and lesions due to falls. Every year 20-30% of the elderly people living alone have falls. The cau...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-07-01 00:00:00
abstract：OBJECTIVE:The atherosclerosis is the most common cause of death and disability in developed countries by causing ischemic cardiopathic and stroke. The ischemic atherotrombotic stroke is the most frequent form of the last one. In this sense we review herein the mechanisms underlying the artherosclerotic process. DEVELO...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:The incidence of deep vein thrombosis and pulmonary embolism in patients with cerebral neoplasia has been estimated at 120/100,000 (the second highest rate for any kind of malignant neoplasia). A timely diagnosis is an indispensable requisite in the clinical evaluation of neurological patients. Patients su...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-01 00:00:00
abstract：AIM:To assess the budget impact of the treatment for relapsing remitting multiple sclerosis (RRMS), interferons, and glatiramer acetate, from the National Health System perspective in Spain. PATIENTS AND METHODS:A budget impact model was designed to compare the cost of RRMS treatment in different settings, using a fiv...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Congenital hydrocephalus or ventriculomegaly is a disorder that now can be diagnosed in uterus with ultrasonography, this gives the chance of being able to give a treatment the earliest as possible. DEVELOPMENT:The clinical manifestations are reviewed, the diagnosis, the frequent treatment and causes of c...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-10 00:00:00
abstract：INTRODUCTION:Visual phenomena can be symptoms of epileptic seizures, although with an uncertain clinical meaning and relationship with the epileptogenic focus. AIMS:To describe the clinical implications of visual epileptic seizures according to their signs and symptoms in adults. PATIENTS AND METHODS:Data were collec...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-03-16 00:00:00
abstract：:The presence of oligoclonal bands (OCB) of immunoglobulin G (IgG) is in our days the most useful finding in the study of the CSF for the diagnosis of multiple sclerosis (MS). The most sensitive method for the detection of OCB is the isoelectric focusing followed by immunoblotting. The prevalence of OCB changes in diff...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-06-16 00:00:00
abstract：OBJECTIVES:To review current knowledge regarding the mechanisms of action, pharmacokinetics, clinical efficacy and the tolerance of topirimate (TPM) and describe the Spanish experience of the use of this drug in 224 patients of all ages. DEVELOPMENT:TPM is a new drug which affects practically all the mechanisms involv...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：INTRODUCTION:Atherosclerosis is a generalized vascular disorder which tends to be localized to specific arterial territories. At the bifurcation of the carotid artery there is a marked predisposition to form plaques of atheroma on the postero-external wall. This tendency is due to the kinematics of fluids and their par...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：INTRODUCTION:Cultural manifestations are frequently used as a source of descriptors in the field of the health sciences. The story of Odysseus (Ulysses) is one of the oldest and most influential works of world literature and has given rise to many subsequent creations, with strong roots in popular culture. AIMS:To con...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.7103.2020187
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:Although there is agreement that working memory in older adults diminished with age, there is still controversy whether this reduction occurs equally for all kind of information or it is more pronounced for a particular type of information. AIM:To compare verbal working memory with visual and spatial work...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-02-01 00:00:00
abstract：INTRODUCTION:The Real Ordinance 2070/1999 meant an important modification in the legislation, when including transcranial Doppler (TCD) in explorations to confirm the clinical diagnosis of brain death (BD). Habitually for their employment in the diagnosis of BD, we look for blood flow signal from the middle cerebral ar...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-11-16 00:00:00
abstract：INTRODUCTION:Semi-structured questionnaires, based on clinical criteria are used in the diagnosis of headache, but none has been used to study the two commonest types of chronic headache. The first step, before clinical application, is to carry out a study of the questionnaire's validity and predictive value. OBJECTIV...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：INTRODUCTION:Hypnosis is a well known and efficient psychotherapeutic treatment. It has been stated as useful in memory improvement, however, there are only a few reports of this method in teaching, and its neurophysiological aspects. OBJECTIVE:In this paper, the authors were intended to deal with some students' acade...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：AIMS:To review the fundamentals of occupational therapy (OT) and to present its possible contributions in the field of neurological rehabilitation. DEVELOPMENT:As its name suggests, OT is a form of treatment that makes use of occupations. Furthermore, occupation is a purpose itself, since OT seeks to adapt the individ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-08-16 00:00:00
abstract：TITLE:Síndrome de depleción de ADN mitocondrial tipo 13: un caso con un inicio poco común. : ...
journal_title：Revista de neurologia
pub_type： 信件
doi：10.33588/rn.6910.2019221
更新日期：2019-11-16 00:00:00
abstract：INTRODUCTION:Parkinson's disease (PD) is a common neurodegenerative disease which begins in adulthood. Its incidence in Mexico is estimated to be 40-50 cases per 100,000 inhabitants/year and is the fourth reason for medical care in the National Institute of Neurology and Neurosurgery. The protein alpha-synuclein, SNCA,...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2016-10-16 00:00:00
abstract：OBJECTIVE:To present the first Spanish case, perhaps the first non-Canadian, with ataxia type Charlevoix-Saguenay. CLINICAL CASE:A patient with important psychomotor delay and non-progressive ataxia has been studied in our Service during the first years of life and his follow-up has been carried out until 30 years of ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2000-07-01 00:00:00
abstract：INTRODUCTION:In the last years, the changes in glial cells during different alterations in the Central Nervous System have been studied. It is known that astrocytes and microglial cells are the glial cells which present the major reactivity. OBJECTIVE:The aim of this work was to analyze the glial cell changes induced ...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1999-09-01 00:00:00
abstract：OBJECTIVE:To show the disorders of the brain cortical development and the possible origin in base to a large series studied in a Pediatric Neurology service. PATIENTS AND METHODS:A series of 144 children with ages ranging between newborn and 12 years was studied from the clinic, image (MR, 3DMR) and evolutive point of...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-16 00:00:00
abstract：INTRODUCTION:Studies about childhood epilepsy with centrotemporal spikes (CECTS), most of them retrospective, include patients with highly heterogeneous features. AIM:To investigate the prognostic value of objective diagnostic criteria for CECTS applied at six month of evolution of epilepsy. PATIENTS AND METHODS:All ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：10.33588/rn.7006.2019357
更新日期：2020-03-16 00:00:00
abstract：AIMS:To appraise the attention deficit hyperactivity disorder assessment scale for a teenage population, EDAH (a). SUBJECTS AND METHODS:From an initial sample of 3400 participants, a final sample of 2292 pupils between 12 and 16 years of age were finally selected. Of the total number, 1066 were boys (46.5%) and 1226 w...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2010-09-16 00:00:00
abstract：INTRODUCTION:The retina is a neuronal membrane that covers the posterior part of the eye chamber and is formed by several layers. The retinal function can be synthesize as the light translation into nervous impulses in the optic nerve. MATERIAL AND METHODS:The ERG is the expression of the changes of the electrical pot...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-01 00:00:00
abstract：INTRODUCTION:Subacute sclerosing panencephalitis (SSPE) is a chronic neurodegenerative disease secondary to an infection of the central nervous system by the measles virus, with no effective treatment. The introduction of therapy with intraventricular interferon alpha (IFN-alpha) and its later association with ribaviri...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2006-03-01 00:00:00
abstract：INTRODUCTION:Vascular pathology is considered to be uncommon, with a much lower incidence than cerebral vascular pathology. PATIENTS AND METHODS:We reviewed the clinical histories of patients with a clinical diagnosis of spinal cord infarction-ischemia attended by the Neurology Department and the Neuropaediatric secti...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-11-16 00:00:00
abstract：:Autism spectrum disorder (autism) is a highly prevalent and heterogeneous family of neurodevelopmental disorders of genetic origins with potentially devastating implications for child, family, health and educational systems. Despite advances in paper-and-pencil screening and in standardization of diagnostic procedures...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2015-02-25 00:00:00
abstract：INTRODUCTION:The diagnosis of attention deficit disorder with or without hyperactivity (ADHD) is a controversial process that may be conditioned to a certain extent by the system of diagnostic classification, by the measuring instrument, by the population that has been chosen for study and by the source of information....
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-11-16 00:00:00
abstract：INTRODUCTION:The relationship between headache and sleep is complex and runs in two directions. Headache may be the consequence of a (primary or secondary) sleep disorder or its cause (in chronic tension-type headache and/or chronic migraine with or without painkiller abuse). It can also be related to sleep in an intri...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2008-09-16 00:00:00
