Abstract:
:Within the bullfrog semicircular canal crista, hair cell tuft types were defined and mapped with the aid of scanning electron microscopy. Intracellular recording and Lucifer Yellow labeling techniques were used to study afferent responses and arborization patterns. Dye-filled planar afferent axons had mean distal axonal diameters of 1.6-4.9 microns, highly branched arbors, and contacted 11-24 hair cells. Dye-filled isthmus afferent axons had mean distal axonal diameters of 1.8-7.9 microns, with either small or large field arbors contacting 4-9 or 25-31 hair cells. The estimated mean number of contacts per innervated hair cell was 2.2 for planar and 1.3 for isthmus afferent neurons. Data on evoked afferent responses were available only for isthmus units that were observed to respond to our microrotational stimuli (less than 3 degrees/s peak rotational velocity). Of 21 such afferent neurons, 8 were successfully dye-filled. Within this small sample, high-gain units had large field arbors and lower-gain units had small field arbors. The sensitivity of each afferent neuron was analyzed in terms of noise equivalent input (NEI), the stimulus amplitude for which the afferent response amplitude is just equivalent to the RMS deviation of the instantaneous spike rate. NEI for isthmus units varied from 0.63 to 8.2 degrees/s; the mean was 3.2 degrees/s.
journal_name
Brain Resjournal_title
Brain researchauthors
Myers SF,Lewis ERdoi
10.1016/0006-8993(90)90107-msubject
Has Abstractpub_date
1990-11-26 00:00:00pages
15-24issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(90)90107-Mjournal_volume
534pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract::Nocistatin, a product of the same precursor as nociceptin/orphanin FQ (N/OFQ), has been shown to antagonize effects of N/OFQ. N/OFQ stimulates feeding, most probably by inhibiting activation of neurons containing oxytocin (OT) and vasopressin (VP), peptides considered as satiety factors, and implicated in the developm...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(00)02535-x
更新日期:2000-07-28 00:00:00
abstract::Postsynaptic potentials were evoked in neostriatal neurons by stimulation of the ipsilateral and contralateral medial agranular frontal cortical field (AGm) in the rat. This cortical region is known to project bilaterally to the dorsal lateral head of the caudate-putamen of rats. Ipsilateral stimulation of AGm should ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(86)91593-3
更新日期:1986-03-05 00:00:00
abstract::The volume of nucleus HVc of the avian song system varies greatly both among and within songbird species, and is positively correlated to song complexity in many species. Moreover, the number of neurons in HVc predicts the ability of individual zebra finches to imitate song accurately. To better understand this brain/...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02488-x
更新日期:2001-06-22 00:00:00
abstract::The ependymocytes lining the central canal of the spinal cord in rats have prominent F-actin networks in the apical cytoplasm, exhibiting significant regional heterogeneity between differing spinal levels. It is not clear when and how this regional heterogeneity develops. We examined F-actin in the central canal durin...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2008.08.045
更新日期:2008-11-06 00:00:00
abstract::Considerable knowledge exists concerning the events mediating neuron death following a necrotic insult; prompted by this, there have now been successful attempts to use gene therapy approaches to protect neurons from such necrotic injury. In many such studies, however, it is not clear what sequence of cellular events ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(01)02572-0
更新日期:2001-07-20 00:00:00
abstract::Previous studies have shown behavioral changes in pre- and postnatal rats exposed to morphine before and during gestation. The present study has attempted to discover morphological correlates of these changes in the fetal rat spinal cord. Pregnant Wistar rats were injected subcutaneously on days 12-18 of gestation wit...
journal_title:Brain research
pub_type: 杂志文章
doi:
更新日期:1980-11-24 00:00:00
abstract::In auditory speech processing, phonological stress functions as an attention holding cue, which facilitates detection of mispronunciations and phonetic deviants in strong syllables as compared to weak ones. Whereas silent reading involves activation of phonological information including word stress, it is not clear wh...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.01.003
更新日期:2016-04-01 00:00:00
abstract::A growth hormone (GH) injection is able to induce the phosphorylated form of the signal transducer and activator of transcription 5 (pSTAT5) in a large number of cells throughout the mouse brain. The present study had the objective to map the distribution of GH-responsive cells in the brain of rats that received an in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2020.147189
更新日期:2021-01-15 00:00:00
abstract::Previous studies have suggested that cardiovascular responses elicited by injection of glycine into the nucleus tractus solitarii (NTS) depend upon interactions between glycinergic and cholinergic neuronal elements in NTS. Release of acetylcholine in response to glycine is one such interaction that has been shown in s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)91789-2
更新日期:1994-07-11 00:00:00
abstract::In a previous study we reported significant elevations of TRH in neocortex, hippocampus and combined amygdala/pyriform cortex in rats 48 h after the last of a series of stage 5 kindled seizures. In the present study, to determine whether the increases in TRH were proportional to the intensity of the convulsions, and t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91330-j
更新日期:1990-08-13 00:00:00
abstract::Our recent study has shown that many afferent fibers in the ventral root are third branches of dorsal root ganglion cells in addition to their processes in the peripheral nerve and the dorsal root. From results of this study, we hypothesized that most of the afferent fibers in the normal ventral root are extra process...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(89)91030-5
更新日期:1989-10-30 00:00:00
abstract::Structural and functional alterations of the putamen have been reported in patients with attention deficit hyperactivity disorder (ADHD), but the functional relationships between this area and other brain regions are seldom explored. In the present study, seed-based correlation analyses were performed in the resting-s...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2009.08.029
更新日期:2009-12-15 00:00:00
abstract::Recent studies have reported microglia that are activated in the central nervous system (CNS) in patients with temporal lobe epilepsy and animal models of epilepsy. However, limited data are available on the dynamic changes of the proportions of various phenotypes of microglia throughout epileptogenesis and whether IL...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2016.12.006
更新日期:2017-02-15 00:00:00
abstract::The nucleus of the solitary tract (NTS) is a critical structure involved in coordinating autonomic and visceral activities. Previous independent studies have demonstrated efferent projections from the NTS to the nucleus paragigantocellularis (PGi) and the central nucleus of the amygdala (CNA) in rat brain. To further ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.08.051
更新日期:2006-10-30 00:00:00
abstract::Evidence is provided that carbonic anhydrase-II is localized in the central nervous system to wide spread systems of oligodendrocytes and restricted astroglia populations, involving both fiber bundles and neuropil. It is suggested that CO2 formed in activated axons may, via carbonic anhydrase-II, give rise to protons ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)00026-m
更新日期:1995-04-03 00:00:00
abstract::Repeated odorant or electrical stimulation of the frog olfactory nerve leads to long-lasting reduction of excitability of the receptor neurons. In the turtle olfactory nerve electrical stimulation causes an increase in extracellular potassium concentration due to the efflux of potassium from active axons. Elevated pot...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)90340-h
更新日期:1990-12-24 00:00:00
abstract::Rab3A is a synaptic vesicle-associated GTP-binding protein thought to be involved in modulation of presynaptic transmitter release through regulation of vesicle trafficking and membrane fusion. Electrophysiological studies at central nervous system synapses of Rab3A null-mutant mice have indicated that nerve stimulati...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2006.03.055
更新日期:2006-05-17 00:00:00
abstract::The role of glial cells in nitric oxide production in the cerebellum of conscious rats was investigated with a glial selective metabolic inhibitor, fluorocitrate. The levels of nitric oxide metabolites (nitrite plus nitrate) in the dialysate following in vivo microdialysis progressively increased to more than 2-fold t...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)00372-7
更新日期:1997-07-11 00:00:00
abstract::The cockroach can reduce the amount of sensory activity received by its CNS from the cerci, paired wind-responsive appendages. This reduction is produced by medial displacement of the cerci, a movement the animal performs naturally during flying. We demonstrate here that this sensory reduction significantly reduces ac...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(88)91009-8
更新日期:1988-02-09 00:00:00
abstract::This study is focused to learn about the cellular localization of transcription factors binding to the cAMP response element-CREBs-in the brain of normal rats and in animals subjected to excitotoxic cell damage. For this purpose, CREB-1 and CREB-2 immunoreactivity is examined in the developing and adult rat brain unde...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(95)01527-2
更新日期:1996-03-11 00:00:00
abstract::Mouse neopallium was disaggregated at 3 developmental stages (E15, E18, PO) and grown in colony cultures for 7 days. On the seventh day of culturing the colonies of cells were transplanted into the cerebellums of neonatal mice. After 3 weeks the astrocytes within the transplants were identified with GFAP immunoperoxid...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(83)90096-2
更新日期:1983-01-01 00:00:00
abstract::The total number of neurosensory cells in the mouse vomeronasal organ was estimated during postnatal development by counting the cell density and measuring the total volume of the neurosensory cell layer. There is a 43% increase in neurosensory cell number between 1 and 4 months of age, followed by a 21% fall in cell ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)90675-7
更新日期:1980-03-03 00:00:00
abstract::Using the passive avoidance learning task in rats, the role of brain somatostatin in cognitive function was investigated with special reference to that of the brain cholinergic system. In addition, the involvement of both the brain somatostatinergic and cholinergic systems in the anti-amnesic action of a newly introdu...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)90900-8
更新日期:1994-04-11 00:00:00
abstract:BACKGROUND:Metabolites involved in one-carbon metabolism (OCM) may predict cognitive prognosis in dementia. The link between OCM, apolipoprotein E (APOE), and DNA methylation creates a biologically plausible mechanism of interaction. AIM:To assess OCM metabolites as predictors of 5-year cognitive prognosis in patients...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/j.brainres.2019.146519
更新日期:2020-01-01 00:00:00
abstract::In the present study, the role of medial septal receptors in behaviour-induced increase in acetylcholine (ACh) release in hippocampus was investigated using dual-probe microdialysis in combination with a simple behavioural procedure. gamma-Aminobutyric acid (GABA) and glutamate receptor agonists and antagonists were a...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/s0006-8993(97)01445-5
更新日期:1998-04-06 00:00:00
abstract::The present work shows the existence of adenosine-dependent cyclic adenosine monophosphate (AMP) accumulation in the chick optic tectum. When tecta from 18-day-old embryos were incubated with the phosphodiesterase inhibitor IBMX and RO 20-1724, the cyclic AMP level increased from 39.2 to 73.3 and 285.5 pmol/mg protein...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0165-3806(87)90016-2
更新日期:1987-09-01 00:00:00
abstract::(1) Synaptic transmission was studied in isolated transverse hippocampal slices from guinea pigs. Extracellular evoked potentials were recorded in the region CA1. (2) Changing the normal perfusion solution (containing 2 mM Ca2+) to calcium-free Ringer abolished synaptic transmission which was again restored by adding ...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(80)91327-x
更新日期:1980-07-21 00:00:00
abstract::In this paper we report on the effects of intra-VTA infusion of opioid agonists on rat ingestive behavior in a variety of experimental contexts. When the animals were tested outside of their home cages surrounded only by food-pellets (Experiment 1), the injection of the mu-opioid agonist DAMGO, but not the kappa-opioi...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(94)01281-l
更新日期:1995-01-30 00:00:00
abstract::Cardiovascular responses to electrical microstimulation of the ventrolateral medulla were investigated in both Wistar-Kyoto rats (WKY) and spontaneously hypertensive rats (SHR) under pentobarbital anesthesia. The threshold intensity required to elicit a change in blood pressure (BP) and the cardiovascular responses in...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91582-2
更新日期:1990-07-02 00:00:00
abstract::gamma-Aminobutyric acid (GABA), pentobarbital and ethanol were applied by bath superfusion to rat locus coeruleus (LC) neurons in a brain slice preparation. The GABA-induced current and conductance increase was measured with single-electrode voltage clamp. Pentobarbital potentiated the GABA-induced current and conduct...
journal_title:Brain research
pub_type: 杂志文章
doi:10.1016/0006-8993(90)91044-h
更新日期:1990-05-28 00:00:00