Cell-mediated and humoral immune responses to total hip replacement under spinal or general anaesthesia.

Abstract:

:Regional anaesthesia has many advantages over general anaesthesia in hip surgery. When the effects of total hip replacement under spinal or general anaesthesia were compared in 22 patients, the only difference between the groups occurred in PHA-induced lymphocyte proliferative responses. In contrast, no differences between the groups were observed in leucocyte or differential counts, lymphocyte or subtype counts, most mitogen-induced lymphocyte proliferative responses, NK-cell activity, IgG, IgM or IgA production by unstimulated or PWM-stimulated lymphocytes, proliferative responses of control lymphocytes with 15% patient serum, or chemiluminescence values in phagocytosis of zymosan opsonized with patient serum. Thus, regional anaesthesia is indicated in total hip replacement for reasons other than the immune response.

authors

Salo M,Nissilä M

doi

10.1111/j.1399-6576.1990.tb03078.x

subject

Has Abstract

pub_date

1990-04-01 00:00:00

pages

241-8

issue

3

eissn

0001-5172

issn

1399-6576

journal_volume

34

pub_type

临床试验,杂志文章,随机对照试验
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