Review article: management of hepatic disease following haematopoietic cell transplant.

abstract：BACKGROUND:Although highly prevalent, little is known about the economic impact of functional dyspepsia (FD). AIMS:To quantify FD patients' health care utilisation patterns and to estimate direct and indirect costs of FD to patients. METHODS:ICD-9 codes identified adult patients with dyspepsia. A validated questionna...

journal_title：Alimentary pharmacology & therapeutics

authors： Lacy BE,Weiser KT,Kennedy AT,Crowell MD,Talley NJ

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:It is not clear which dose of clarithromycin (500 mg b.d. or 250 mg b.d.) is more effective for Helicobacter pylori eradication in proton pump inhibitor-based triple therapies. METHODS:We undertook a meta-analysis of the effect of 7-day triple therapies consisting of a proton pump inhibitor (P), and clarith...

journal_title：Alimentary pharmacology & therapeutics

authors： Huang J,Hunt RH

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The presenting symptoms of coeliac disease are often subtle and the diagnosis is frequently delayed or overlooked. Therefore, especially elderly patients may be denied the benefits conferred by gluten free diet which can be dramatically life-changing. AIM:To review the occurrence, clinical features, diagnos...

journal_title：Alimentary pharmacology & therapeutics

authors： Collin P,Vilppula A,Luostarinen L,Holmes GKT,Kaukinen K

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal bleeding is a common medical emergency associated with substantial mortality. Tranexamic acid may be effective for reducing mortality in upper gastrointestinal bleeding. AIM:To examine the effects of tranexamic acid in upper gastrointestinal bleeding by systematic review and meta-anal...

journal_title：Alimentary pharmacology & therapeutics

authors： Twum-Barimah E,Abdelgadir I,Gordon M,Akobeng AK

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Few studies have evaluated interferon and ribavirin therapy in hepatitis C virus-infected patients with persistently normal alanine aminotransferase (ALT) levels. AIM:To determine the efficacy and safety of combination therapy in this population, and to evaluate the impact of treatment on health-related qua...

journal_title：Alimentary pharmacology & therapeutics

authors： Bini EJ,Mehandru S

更新日期：2006-03-15 00:00:00

abstract：BACKGROUND:Combination treatment with azathioprine for 6-12 months is the preferred strategy for starting infliximab due to improved pharmacokinetics. However, optimised infliximab monotherapy with proactive dose escalations in case of low trough levels is a safer but under-studied alternative. AIM:To compare the clin...

journal_title：Alimentary pharmacology & therapeutics

authors： Drobne D,Kurent T,Golob S,Švegl P,Rajar P,Hanžel J,Koželj M,Novak G,Smrekar N,Ferkolj I,Štabuc B

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Gastro-oesophageal reflux is thought to cause chronic laryngitis through laryngopharyngeal reflux. Response of laryngitis to treatment with acid-suppressive therapy supports this causal link. AIM:To determine the prevalence of gastro-oesophageal reflux disease in patients with chronic laryngitis and respons...

journal_title：Alimentary pharmacology & therapeutics

authors： Qua CS,Wong CH,Gopala K,Goh KL

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Uninvestigated dyspepsia is common in family practice. The prevalence of clinically significant upper gastrointestinal findings (CSFs) in adult uninvestigated dyspepsia patients, and their predictability based on history, is unknown. METHODS:Prompt endoscopy was performed within 10 days of referral, in 1040...

journal_title：Alimentary pharmacology & therapeutics

authors： Thomson AB,Barkun AN,Armstrong D,Chiba N,White RJ,Daniels S,Escobedo S,Chakraborty B,Sinclair P,Van Zanten SJ

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Recent genome-wide association studies based on adult and paediatric populations have implicated >30 genes/loci as susceptibility loci for Crohn's disease (CD). AIMS:To investigate whether reported genes/loci were also associated with CD in Canadian children. DESIGN AND METHODS:A case-control design was im...

journal_title：Alimentary pharmacology & therapeutics

authors： Amre DK,Mack DR,Morgan K,Israel D,Deslandres C,Seidman EG,Lambrette P,Costea I,Krupoves A,Fegury H,Dong J,Grimard G,Levy E

更新日期：2010-06-01 00:00:00

abstract：:Human triple-lumen intestinal perfusion was used to compare water and solute absorption from the oral rehydration solution (ORS) most widely used in the United Kingdom and a new experimental hypotonic ORS (HYPO-ORS). HYPO-ORS (osmolality 210 mOsm/kg) promoted significantly greater water absorption than UK-ORS (7.03 +/...

journal_title：Alimentary pharmacology & therapeutics

authors： Hunt JB,Elliott EJ,Farthing MJ

更新日期：1989-12-01 00:00:00

abstract：AIM:To determine whether 4 days of quadruple therapy using bismuth, tetracycline and metronidazole combined with omeprazole is effective treatment for Helicobacter pylori infection. METHODS:Non-ulcer dyspepsia, as well as chronic peptic ulcer patients with biopsy-proven H. pylori infection received 4 days of quadruple...

journal_title：Alimentary pharmacology & therapeutics

authors： De Boer WA,Driessen WM,Tytgat GN

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Trials of thymosin treatment in chronic hepatitis B virus infection have been small and the results have been inconsistent. AIM:To conduct a meta-analysis to evaluate the efficacy of thymosin treatment in chronic hepatitis B virus infection. METHODS:Randomized controlled trials comparing thymosin for over ...

journal_title：Alimentary pharmacology & therapeutics

authors： Chan HL,Tang JL,Tam W,Sung JJ

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Early differentiation of malignant from benign bile duct obstruction is of utmost importance. AIM:To identify biochemical and clinical predictors for malignancy in patients with bile duct obstruction, and establish a predictive model by combining pre-treatment patient characteristics. A web-based applicatio...

journal_title：Alimentary pharmacology & therapeutics

authors： Meister T,Uphoff MA,Heinecke A,Domagk D,Kunsch S,Lindhorst A,Ellenrieder V,Heinzow HS

更新日期：2015-05-01 00:00:00

abstract：:Faecal impaction with or without encopresis is a very common problem. We performed a randomized, open-label, prospective study to compare the efficacy and acceptability of the treatment of faecal impaction using either mineral oil or pineapple-flavoured isotonic intestinal lavage solution containing polyethylene glyco...

journal_title：Alimentary pharmacology & therapeutics

authors： Tolia V,Lin CH,Elitsur Y

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available. AIM:To compare the efficacy of terlipressin plus albumin vs. placebo plus albumin in p...

journal_title：Alimentary pharmacology & therapeutics

authors： Sanyal AJ,Boyer TD,Frederick RT,Wong F,Rossaro L,Araya V,Vargas HE,Reddy KR,Pappas SC,Teuber P,Escalante S,Jamil K

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Strong acid inhibition using esomeprazole increases cure rates with triple therapy and 10-day treatments are more effective than 7-day ones. The combination of amoxicillin plus metronidazole at full doses, and using a physiologically-correct schedule three times a day, and has been shown to overcome metronid...

journal_title：Alimentary pharmacology & therapeutics

authors： Sánchez-Delgado J,García-Iglesias P,Castro-Fernández M,Bory F,Barenys M,Bujanda L,Lisozain J,Calvo MM,Torra S,Gisbert JP,Calvet X

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Obscure gastrointestinal bleeding (OGIB) is a commonly encountered clinical problem in gastroenterology and is associated with significant morbidity and mortality. The investigation and management of OGIB has changed dramatically over the past decade with the advent of newer gastroenterological and radiologi...

journal_title：Alimentary pharmacology & therapeutics

authors： Liu K,Kaffes AJ

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Substance P acting via the neurokinin-1 receptor is involved in the development of hyperalgesia, although studies using neurokinin-1 receptor antagonists (NK-1RA) in human somatic pain have been disappointing. AIM:To evaluate whether Substance P is involved in the development of human visceral pain/hyperalg...

journal_title：Alimentary pharmacology & therapeutics

authors： Willert RP,Hobson AR,Delaney C,Hicks KJ,Dewit OE,Aziz Q

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:There is a need for a simple, therapeutic test that is of diagnostic value and can also provide rapid symptom relief in patients who present with classic, mild symptoms suggestive of gastro-oesophageal reflux disease (GERD), when the diagnosis is based on symptom assessment alone. AIM:To assess the diagnost...

journal_title：Alimentary pharmacology & therapeutics

authors： Bate CM,Riley SA,Chapman RW,Durnin AT,Taylor MD

更新日期：1999-01-01 00:00:00

abstract：:Colorectal cancer is a common cancer and common cause of death. The mortality rate from colorectal cancer can be reduced by identification and removal of cancer precursors, adenomas, or by detection of cancer at an earlier stage. Pilot screening programmes have demonstrated decreased colorectal cancer mortality; as a ...

journal_title：Alimentary pharmacology & therapeutics

authors： Nicholson FB,Barro JL,Atkin W,Lilford R,Patnick J,Williams CB,Pignone M,Steele R,Kamm MA

更新日期：2005-12-01 00:00:00

abstract：:Helicobacter pylori produces a 550 kDa, multimeric, nickel-containing urease that catalyses the hydrolysis of urea to yield ammonia and carbonic acid. The ure gene cluster, comprised of seven genes, encodes the two structural subunits UreA (26.5 kDa) and UreB (60.3 kDa), and five accessory proteins: UreI, UreE, UreF, ...

journal_title：Alimentary pharmacology & therapeutics

authors： Mobley HL

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The Th2 allergic pathway in eosinophilic oesophagitis (EoE) responds to food antigen exposure. AIM:To compare the presence and temporal pattern of food antigen penetration in oesophageal mucosa in active and inactive EoE and controls METHODS: Thirty-two patients with EoE (20 active) and 10 controls were ask...

journal_title：Alimentary pharmacology & therapeutics

authors： Ravi A,Marietta EV,Alexander JA,Peterson K,Lavey C,Geno DM,Murray JA,Katzka DA

更新日期：2021-02-01 00:00:00

abstract：:Corticosteroids are highly effective in inducing clinical remission in patients with active Crohn's disease. However, the role of corticosteroids in the treatment of this disease is primarily ameliorative because they are ineffective in maintaining remission or healing mucosal lesions. Nearly half of the patients who ...

journal_title：Alimentary pharmacology & therapeutics

authors： Rutgeerts PJ

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Functional dyspepsia is a heterogeneous condition and a uniform response to drug treatment is not likely. This may be the reason for the general failure of acid suppression in clinical trials in these patients. It may be more rewarding to identify true responders to drug treatment by a single subject trial. ...

journal_title：Alimentary pharmacology & therapeutics

authors： Bytzer P,Hansen JM,Rune S,Bonnevie O,Breinstrup H,Funch-Jensen P,Matzen P,Meineche-Schmidt V,Schaffalitzky De Muckadell OB

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Although lactulose and polyethylene glycol are osmotic laxatives widely used in the treatment of chronic constipation, no study has been conducted to compare their actions on the colonic bacterial ecosystem, which has an important influence on host health. AIM:To assess the effects of lactulose and polyethy...

journal_title：Alimentary pharmacology & therapeutics

authors： Bouhnik Y,Neut C,Raskine L,Michel C,Riottot M,Andrieux C,Guillemot F,Dyard F,Flourié B

更新日期：2004-04-15 00:00:00

abstract：BACKGROUND:Malnutrition/sarcopenia and frailty are common in patients with cirrhosis and are associated with poor outcomes. AIM:To provide an overview of data on the importance, assessment and management of malnutrition/sarcopenia and frailty in cirrhosis. METHODS:A literature search was conducted in PubMed and other...

journal_title：Alimentary pharmacology & therapeutics

authors： Bunchorntavakul C,Reddy KR

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:There are patients with chronic hepatitis C who are not eligible for the current interferon-based therapies or refuse to be treated due to secondary effects. AIM:To provide information on alternative treatments for the management of these patients. METHODS:A PubMed search was performed to identify relevant...

journal_title：Alimentary pharmacology & therapeutics

authors： Carreño V

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Endothelins have been implicated in gastric mucosal damage in a variety of animal models. Exogenous ET-1 and ET-3 are causally associated with experimental gastric ulcers. Furthermore, clinical reports also show elevated plasma and gastric mucosal endothelin-1 levels in patients suffering from peptic ulcers....

journal_title：Alimentary pharmacology & therapeutics

authors： Padol I,Huang JQ,Hunt RH

更新日期：1999-04-01 00:00:00

abstract：:In a double-blind, placebo-controlled study of SK&F 94482 (BMY-25368) (400-mg, post-evening meal, for 7 days in 11 healthy subjects), there was a significant 75% decrease in median integrated 24-h intragastric acidity during dosing with the drug (218 mmol h/L) compared with placebo (883 mmol h/L; P = 0.003). The singl...

journal_title：Alimentary pharmacology & therapeutics

authors： Gavey CJ,Smith JT,Nwokolo CU,Pounder RE

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:Diagnosis of inflammatory bowel disease (IBD) is based on clinical presentation, colonoscopy and histology. Differentiation of Crohn's disease (CD) and ulcerative colitis (UC) can be difficult in some patients. Endoscopic ultrasound (EUS) provides high resolution images of the gastrointestinal wall (GI) and ...

journal_title：Alimentary pharmacology & therapeutics

authors： Ellrichmann M,Wietzke-Braun P,Dhar S,Nikolaus S,Arlt A,Bethge J,Kuehbacher T,Wintermeyer L,Balschun K,Klapper W,Schreiber S,Fritscher-Ravens A

更新日期：2014-04-01 00:00:00