Neuropsychological test profiles in schizophrenia and non-psychotic depression.

Abstract:

OBJECTIVE:The study examined to what degree schizophrenia is characterized by a neuropsychological (NP) test profile specific in shape and level compared with depression and normal functioning. METHOD:Fifty-three patients with schizophrenia, 45 with non-psychotic depression, and 50 normals were assessed with a comprehensive NP test battery and clinical instruments. NP test scores were factor analyzed into seven composite scores. RESULTS:Schizophrenia patients performed significantly below normals across all seven composite scores, whereas depression patients were impaired in two. Verbal memory was most impaired. Sixty-two percent of schizophrenia patients were moderately or severely impaired, the corresponding figure for depression was 28%. Impairment was moderately associated with IQ level and clinical symptom load in schizophrenia, but not in depression. CONCLUSION:Schizophrenia is characterized by deficits across a wide range of NP functions. Thirty-eight percent of the patients are within normal limits. A mild and limited NP disturbance is apparent in depression.

journal_name

Acta Psychiatr Scand

authors

Rund BR,Sundet K,Asbjørnsen A,Egeland J,Landrø NI,Lund A,Roness A,Stordal KI,Hugdahl K

doi

10.1111/j.1600-0447.2005.00626.x

subject

Has Abstract

pub_date

2006-04-01 00:00:00

pages

350-9

issue

4

eissn

0001-690X

issn

1600-0447

pii

ACP626

journal_volume

113

pub_type

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