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Quinol fatty alcohols as promoters of axonal growth.

Abstract：

:The synthesis of three series of quinol fatty alcohols (QFAs) and their biological activities on the promotion of axonal growth are described. Interestingly, the 15-(2,5-dimethoxyphenyl)pentadecan-1-ol, the QFA bearing 15 carbon atoms on the side chain (n=15), shows the most potent promotion of axonal growth in the presence of both permissive and non-permissive naturally occurring substrates such as Sema3A and myelin proteins.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Hanbali M,Vela-Ruiz M,Bagnard D,Luu B

doi

10.1016/j.bmcl.2006.02.041

subject

Has Abstract

pub_date

2006-05-15 00:00:00

pages

2637-40

issue

10

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(06)00228-9

journal_volume

16

pub_type

杂志文章

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