Studies on the novel anti-staphyloccal compound nematophin.

Abstract:

:A number of analogues of the recently described compound nematophin were prepared and studied for antibacterial activity. The 2-phenyl derivative was found to exhibit exceptional activity against methicillin resistant Staphylococcus aureus (MRSA) whereas the isosteric benzimidazole analogue was much less active.

journal_name

Bioorg Med Chem Lett

authors

Kennedy G,Viziano M,Winders JA,Cavallini P,Gevi M,Micheli F,Rodegher P,Seneci P,Zumerle A

doi

10.1016/s0960-894x(00)00331-0

subject

Has Abstract

pub_date

2000-08-07 00:00:00

pages

1751-4

issue

15

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(00)00331-0

journal_volume

10

pub_type

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