Effect of antireceptor antibodies in dilated cardiomyopathy on the cycling of cardiac beta receptors.

abstract：:The neutral alkaloid, ryanodine, has several actions on cardiac muscle. To delineate better its mode of action, we studied ryanodine's effect upon contracting cat papillary muscles under changing loading conditions and stimulation frequencies. We also studied ryanodine's physiologic and metabolic effects upon isolated...

journal_title：American heart journal

authors： Blumlein SL,Sievers R,Wikman-Coffelt J,Parmley WW,Rouleau JL

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Appropriate dietary recommendations represent a key part of secondary prevention in cardiovascular disease (CVD). We evaluated the effectiveness of the implementation of a nutritional program on quality of diet, cardiovascular events, and death in patients with established CVD. METHODS:In this open-label, m...

journal_title：American heart journal

authors： Weber B,Bersch-Ferreira ÂC,Torreglosa CR,Marcadenti A,Lara ES,da Silva JT,Costa RP,Santos RHN,Berwanger O,Bosquetti R,Pagano R,Mota LGS,de Oliveira JD,Soares RM,Galante AP,da Silva SA,Zampieri FG,Kovacs C,Amparo FC,

更新日期：2019-09-01 00:00:00

abstract：:Oxygen free radical scavengers have been found to decrease infarct size in dogs subjected to myocardial ischemia-reperfusion injury. A baboon open-chest model was used to determine if superoxide dismutase (SOD), an oxygen free radical scavenger, together with catalase would be equally effective in subhuman primates (b...

journal_title：American heart journal

authors： Watanabe BI,Premaratne S,Limm W,Mugiishi MM,McNamara JJ

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Decreased heart rate variability (HRV) is often assumed to be associated with mortality in all patients after myocardial infarction (MI), independent of clinical factors or time after MI. METHOD:HRV was determined from Holter tapes in the Cardiac Arrhythmia Suppression Trial (CAST). Patients were 71 +/- 120...

journal_title：American heart journal

authors： Stein PK,Domitrovich PP,Kleiger RE,CAST Investigators.

更新日期：2004-02-01 00:00:00

abstract：:There are selective blocking agents (antagonists) for alpha receptors and beta receptors. These blocking agents prevent the response to injected agonists and neurogenically released norepinephrine. The principal cardiovascular response to alpha blockade is postural hypotension with reflexly induced cardiac stimulation...

journal_title：American heart journal

authors： Ahlquist RP

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:The aim of this study was to compare rate of onset, magnitude, and consistency of platelet inhibition after administration of prasugrel or clopidogrel and to relate platelet inhibition to systemic exposure to each active metabolite. Thienopyridines are prodrugs, metabolized in vivo to active metabolites that...

journal_title：American heart journal

authors： Brandt JT,Payne CD,Wiviott SD,Weerakkody G,Farid NA,Small DS,Jakubowski JA,Naganuma H,Winters KJ

更新日期：2007-01-01 00:00:00

abstract：:Technetium 99m-Q12 is a new cationic myocardial perfusion imaging agent that produces excellent images in human beings. The purpose of this study was to examine the separate effects of hypoxia and low flow on myocardial clearance kinetics. After a 1 mCi bolus injection, myocardial 99mTc-Q12 clearance was monitored for...

journal_title：American heart journal

authors： Okada RD,Nguyen KN,Lauinger M,Allton IL,Johnson G 3rd

更新日期：1996-07-01 00:00:00

abstract：:We compared the effects of IV digoxin (0.04 mg/kg) and nitroprusside (NP) (1.2 and 1.8 microgram/kg/min) on left ventricular (LV) performance in six preinstrumented conscious dogs with 3 and 6 hours after digoxin administration (serum level, 3.5 +/- 0.6 ng/ml), there were no changes in heart rate, LV systolic (LVSP) a...

journal_title：American heart journal

authors： O'Rourke RA,Badke FR,Forst D

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Systolic wall motion abnormality (WMA) after acute myocardial infarction (AMI) is a major determinant of outcome; the presence and importance of diastolic WMA after AMI are unknown. We therefore sought to detect diastolic WMA using color kinesis and to assess its relation to neurohormonal activation and its ...

journal_title：American heart journal

authors： Husic M,Nørager B,Egstrup K,Lang RM,Møller JE

更新日期：2005-10-01 00:00:00

abstract：:After dipyridamole, canine studies have demonstrated a slower rate of myocardial thallium-201 clearance from zones distal to a coronary artery stenosis compared to normal zones. To determine if criteria based on canine myocardial thallium-201 clearance rates could be applied clinically, 40 patients with and 26 patient...

journal_title：American heart journal

authors： Okada RD,Dai YH,Boucher CA,Pohost GM

更新日期：1984-03-01 00:00:00

abstract：:A morphologic study of 466 cardiac mural thrombi, 66 examples of nonbacterial thrombotic endocarditis, 25 myxomas, and 12 papillary endocardial lesions was performed. It appeared that three different sequences of organization of endocardial thrombi are possible. (1) Ordinary mural thrombi are converted into a flat, fi...

journal_title：American heart journal

authors： Salyer WR,Page DL,Hutchins GM

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:ST-elevation myocardial infarctions (STEMI) caused by proximal left-anterior descending (LAD) lesions have more myocardium at risk and worse outcomes than those located in other segments. The aim is to compare outcomes of patients with STEMI and proximal-LAD lesions treated with bare-metal stents (BMS) versu...

journal_title：American heart journal

authors： Gomez-Lara J,Brugaletta S,Gomez-Hospital JA,Ferreiro JL,Roura G,Romaguera R,Martin-Yuste V,Masotti M,Iñiguez A,Serra A,Hernandez-Antolin R,Mainar V,Valgimigli M,Tespili M,den Heijer P,Bethencourt A,Vazquez N,Serruys P,

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:High-sensitivity C-reactive protein (hsCRP) is promoted as an independent predictor of atherosclerotic risk. In addition, cardiorespiratory fitness is inversely related to hsCRP in single-sex cross-sectional analyses. Our objective was to determine if modulating fitness with exercise training imposes changes...

journal_title：American heart journal

authors： Huffman KM,Samsa GP,Slentz CA,Duscha BD,Johnson JL,Bales CW,Tanner CJ,Houmard JA,Kraus WE

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Experimental studies suggest that metabolic myocardial support by intravenous (IV) glucose, insulin, and potassium (GIK) reduces ischemia-induced arrhythmias, cardiac arrest, mortality, progression from unstable angina pectoris to acute myocardial infarction (AMI), and myocardial infarction size. However, tr...

journal_title：American heart journal

authors： Selker HP,Beshansky JR,Griffith JL,D'Agostino RB,Massaro JM,Udelson JE,Rashba EJ,Ruthazer R,Sheehan PR,Desvigne-Nickens P,Rosenberg YD,Atkins JM,Sayah AJ,Aufderheide TP,Rackley CE,Opie LH,Lambrew CT,Cobb LA,Macleod BA

更新日期：2012-03-01 00:00:00

abstract：:Percutaneous transluminal coronary recanalization, a new therapeutic procedure used in acute myocardial infarction, offers significant reduction in mortality, as well as more effective limitation of the zone of infarction than has been possible with other pharmacologic treatment employed in the past. The risk of coron...

journal_title：American heart journal

authors： Rutsch W,Schartl M,Mathey D,Kuck K,Merx W,Dörr R,Rentrop P,Blanke H

更新日期：1981-12-01 00:00:00

abstract：:Although the Doppler mitral flow velocity pattern changes in accordance with the degree of left ventricular diastolic dysfunction, it is "normalized" in the presence of heart failure. In this study the pulmonary venous flow velocity pattern was characterized in 43 hypertensive patients with and without heart failure t...

journal_title：American heart journal

authors： Masuyama T,Lee JM,Yamamoto K,Tanouchi J,Hori M,Kamada T

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Erectile dysfunction (ED) is a common disorder in middle-aged men and is significantly influenced by cardiovascular risk factors (CVRFs) and cardiovascular disease. The substudy of the ONTARGET/TRANSCEND trials evaluates the relationship of erectile function to baseline characteristics and current treatment ...

journal_title：American heart journal

authors： Böhm M,Baumhäkel M,Probstfield JL,Schmieder R,Yusuf S,Zhao F,Koon T,ONTARGET\/TRANSCEND ED-Investigators.

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Carvedilol therapy during congestive heart failure demonstrated a good efficacy in mortality rate reduction and in improvement of left ventricular (LV) systolic performance. However, currently there is not any finding about the drug's effect on diastolic filling. The aim of this study was to evaluate the eff...

journal_title：American heart journal

authors： Palazzuoli A,Carrera A,Calabria P,Puccetti L,Pastrorelli M,Pasqui AL,Auteri A,Bruni F

更新日期：2004-01-01 00:00:00

abstract：:This study assesses the significance of inferior ST-segment depression during anterior acute myocardial infarction (AMI) by investigating the relationship between inferior ST-segment depression and (1) the site of the left anterior descending (LAD) coronary artery lesion and (2) ST-segment deviation in the various ant...

journal_title：American heart journal

authors： Birnbaum Y,Solodky A,Herz I,Kusniec J,Rechavia E,Sulkes J,Sclarovsky S

更新日期：1994-06-01 00:00:00

abstract：:Oxygen has long been assumed beneficial for all ill and injured patients. However, hyperoxia may be harmful and aggravate myocardial injury such as that caused by myocardial infarction. We aimed to investigate if hyperoxia increases myocardial injury following direct current cardioversion compared with room air. METH...

journal_title：American heart journal

authors： Lauridsen KG,Schmidt AS,Adelborg K,Bach L,Hornung N,Jepsen SM,Deakin CD,Rickers H,Løfgren B

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) remains a major public health issue. Data on long-term trends in the incidence of HF and survival after its onset are limited. METHODS:A prospective cohort study conducted between 1985 and 2004 in 21,906 participants of the Physicians' Health Study I who were alive and free of HF on Janua...

journal_title：American heart journal

authors： Djoussé L,Kochar J,Gaziano JM

更新日期：2007-11-01 00:00:00

abstract：:Adverse drug events affect millions of patients each year. An important drug-drug interaction between amiodarone and vitamin K antagonists is encountered frequently in daily clinical practice. Warfarin, a commonly used anticoagulant, is a mixture of 2 optically active isomers (R and S enantiomers). The S enantiomer is...

journal_title：American heart journal

authors： Shirolkar SC,Fiuzat M,Becker RC

更新日期：2010-10-01 00:00:00

abstract：:In chronic heart failure (CHF) the contributing role of increased sympathetic activity and hemodynamic dysfunction in the genesis of ventricular arrhythmias has not been well established. To assess the relation between severe ventricular arrhythmias, hemodynamic impairment, and autonomic nervous system derangement, 14...

journal_title：American heart journal

authors： Mortara A,La Rovere MT,Pinna GD,Parziale P,Maestri R,Capomolla S,Opasich C,Cobelli F,Tavazzi L

更新日期：1997-11-01 00:00:00

abstract：:Three cases of rupture of the interventricular septum occurring coincident with acute inferior myocardial infarction are reported and the relevant literature is reviewed. One patient under-went successful surgical repair and, in addition, had an aneurysmectomy. Clues and pitfalls in diagnosis as well as the possible c...

journal_title：American heart journal

authors： Longo EA,Cohen LS

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Chronic infection with Chlamydia pneumoniae (Cpn) has been associated with atherosclerotic cardiovascular disease in sero-epidemiological, pathological and animal-model studies. Inflammation and immune activation has been proposed as the pathophysiological link between chronic infection and atherosclerosis. ...

journal_title：American heart journal

authors： Smith DA,Zouridakis EG,Mariani M,Fredericks S,Cole D,Kaski JC

更新日期：2003-07-01 00:00:00

abstract：:A large series of 306 patients with ischemic heart disease was studied with automated systolic time intervals and left ventricular ejection fraction as determined by the angiocardiographic method. It was found the pre-ejection period, left ventricular ejection time, delta values, and PEP/LVET ratio all were related to...

journal_title：American heart journal

authors： Swatzell RH Jr,Bancroft WH Jr,Baldone JC Jr,Tucker MS

更新日期：1977-04-01 00:00:00

abstract：:Previous studies have suggested that the contractility of isolated heart muscle removed from rabbits made hypercholesterolemic is decreased. As part of a study evaluating the effects of high-lipid diets on aortic atherosclerosis, we evaluated the contractility of perfused rabbit hearts. Six rabbits were placed on a hi...

journal_title：American heart journal

authors： Blumlein S,Sievers R,Wikman-Coffelt J,Parmley WW

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:A common regimen for patients requiring dual-antiplatelet therapy who are at risk for gastrointestinal complications is the synchronous administration of enteric-coated (EC) aspirin, a proton pump inhibitor, and clopidogrel, although proton pump inhibitors have the potential for pharmacodynamic interaction w...

journal_title：American heart journal

authors： Gurbel PA,Bliden KP,Fort JG,Jeong YH,Shuldiner A,Chai S,Gesheff T,Antonino M,Gesheff M,Zhang Y,Tantry US

更新日期：2013-02-01 00:00:00

abstract：:Antiplatelet therapy has been shown to significantly reduce the risk of serious vascular events in high-risk patients, including those with a prior acute ischemic event. The long-term use of antiplatelet agents is a key component of secondary prevention measures following acute coronary syndromes, including ST-segment...

journal_title：American heart journal

authors： Valgimigli M,Minarelli M

更新日期：2010-12-01 00:00:00

abstract：:An extremely athletic 56-year-old male physician was found to have profound sinus bradycardia. His only symptom was markedly increased alertness while actively exercising. During pacemaker insertion he had an episode of prolonged sinus arrest terminated by a precordial thump. This case suggests that exercise can alter...

journal_title：American heart journal

authors： Marmor BM,Black MM

更新日期：1980-07-01 00:00:00