Intensive community pharmacy intervention had little impact on triptan consumption: a randomized controlled trial.

Abstract:

OBJECTIVE:To evaluate the impact of an intensive pharmaceutical care campaign targeting inappropriate use of triptans. DESIGN:Randomized controlled trial. SETTING:22 community pharmacies in the County of Funen, Denmark. SUBJECTS:A total of 1123 triptan users at intervention pharmacies and 1340 at control pharmacies. INTERVENTION:Intervention pharmacy staff received information on migraine and other types of headache, detection of inappropriate triptan use and other drug-related problems, and techniques for establishing a dialogue with patients. Intervention consisted of a folder and a structured dialogue with the pharmacy staff. The folder included questions aimed at detecting overuse and inappropriate triptan use. MAIN OUTCOME MEASURES:Change in average triptan consumption in doses per month measured by means of a prescription database with information on all purchases of reimbursed drugs at the level of the individual patient. RESULTS:Overall, intervention had no statistically significant short-term impact on patients' consumption of triptans either among incident users (intervention/control ratio 1.02; 95% confidence interval 0.95 to 1.12), or among prevalent users (1.02; 0.97 to 1.08). No effects were observed after 6 and 9 months, apart from a possible borderline effect after 9 months among prevalent users with intermediate triptan consumption (0.93; 0.87 to 1.00). CONCLUSION:The pharmaceutical care campaign did not reduce the use of triptans.

authors

Søndergaard J,Foged A,Kragstrup J,Gaist D,Gram LF,Sindrup SH,Muckadell HU,Larsen BO,Herborg H,Andersen M

doi

10.1080/02813430500444916

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

16-21

issue

1

eissn

0281-3432

issn

1502-7724

pii

T029355612374087

journal_volume

24

pub_type

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