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A practical and green approach towards synthesis of dihydropyrimidinones: using heteropoly acids as efficient catalysts.

Abstract：

:A simple and green chemistry procedure for the synthesis of dihydropyrimidinones using heteropoly acid mediated cyclocondensation reaction is described. This method provides an efficient and much improved modification of the original Biginelli reaction reported in 1893, in terms of high yields, and short reaction times. It has the ability to allow a wide variety of substitutions in all three components.

journal_name

Bioorg Med Chem Lett

journal_title

Bioorganic & medicinal chemistry letters

authors

Rafiee E,Jafari H

doi

10.1016/j.bmcl.2006.01.087

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

2463-6

issue

9

eissn

0960-894X

issn

1464-3405

pii

S0960-894X(06)00126-0

journal_volume

16

pub_type

杂志文章

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