Different effects of low and high doses of endothelin on haemodynamics and hormones in the normotensive conscious dog.

abstract：BACKGROUND:A recent editorial published by Verma and Strauss, entitled 'Angiotensin receptor blockers and myocardial infarction', examined, through a partial analysis of individual trials, the use of angiotensin receptor blockers (ARBs) in a variety of clinical settings. This editorial was reported widely in the lay pr...

journal_title：Journal of hypertension

authors： Volpe M,Mancia G,Trimarco B

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Arterial stiffness is increased with chronic inflammatory disorders. The reduction of inflammation by immunomodulatory therapy is associated with a restoration of arterial function. The aims of the study were to perform a meta-analysis to determine whether arterial stiffness is increased in patients with inf...

journal_title：Journal of hypertension

authors： Zanoli L,Rastelli S,Granata A,Inserra G,Empana JP,Boutouyrie P,Laurent S,Castellino P

更新日期：2016-05-01 00:00:00

abstract：:Although the blood vessels are exposed to high pressures in hypertension, the main complications of hypertension (stroke and myocardial infarction) are paradoxically thrombotic rather than haemorrhagic. In keeping with Virchow's triad, patients with hypertension do demonstrate abnormalities of vessel wall (endothelial...

journal_title：Journal of hypertension

authors： Lip GY,Li-Saw-Hee FL

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Reductions in albuminuria of more than 30% are considered a strong marker of delay of chronic kidney disease (CKD) progression. Single renin-angiotensin system (RAS) blockade represents the cornerstone of CKD treatment. However, as CKD progression still occurs, other nephroprotective options were explored; m...

journal_title：Journal of hypertension

authors： Alexandrou ME,Papagianni A,Tsapas A,Loutradis C,Boutou A,Piperidou A,Papadopoulou D,Ruilope L,Bakris G,Sarafidis P

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Spontaneously hypertensive rats (SHR) are sensitive to a high salt intake and we investigated the question of whether flow-induced dilation is affected by this type of diet, as flow responses are especially sensitive to small changes in extracellular sodium concentrations. METHODS:We evaluated the effects of...

journal_title：Journal of hypertension

authors： Matrougui K,Lévy BI,Schiavi P,Guez D,Henrion D

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:We examined the relationship between brachial-ankle pulse wave velocity and the development of cardiovascular disease in a general Japanese population. METHODS:A total of 2916 community-dwelling Japanese individuals without history of cardiovascular disease aged at least 40 years were followed up for an aver...

journal_title：Journal of hypertension

authors： Ninomiya T,Kojima I,Doi Y,Fukuhara M,Hirakawa Y,Hata J,Kitazono T,Kiyohara Y

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:To determine the effects of angiotensin II (AII) (1-8) on cytosolic free calcium concentrations in the absence and in the presence of the selective angiotensin subtype 1 (AT1) receptor antagonist losartan and of the selective angiotensin subtype 2-receptor antagonist P-186 in human peripheral blood mononuclea...

journal_title：Journal of hypertension

authors： Lijnen P,Fagard R,Petrov V

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:A previous history of hypertension is overrepresented among patients with ischaemic heart disease. The present study aims at describing the influence of a previous history of hypertension upon the prognosis among patients hospitalized due to acute myocardial infarction. DESIGN:Patients were followed for 1 y...

journal_title：Journal of hypertension

authors： Herlitz J,Karlson BW,Richter A,Wiklund O,Jablonskiene D,Hjalmarson A

更新日期：1992-10-01 00:00:00

abstract：PURPOSE:To study the feasibility of vascular mechanics at the aortic arch with two-dimensional speckle tracking echocardiography, as well as to define normal values and to compare results between hypertensive patients and healthy patients. METHODS:We included 107 patients (61 healthy patients and 46 hypertensive patie...

journal_title：Journal of hypertension

authors： Teixeira R,Monteiro R,Baptista R,Pereira T,Ribeiro MA,Gonçalves A,Cardim N,Gonçalves L

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:(1) To compare urinary guanosine 3',5' cyclic monophosphate (cyclic GMP) excretion between normotensive subjects and essential hypertensive patients; (2) to determine the influence of changes in sodium intake on urinary cyclic GMP excretion in response to the neutral endopeptidase inhibitor candoxatril in es...

journal_title：Journal of hypertension

authors： Sagnella GA,Singer DR,Markandu ND,Buckley MG,MacGregor GA

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVE:Low insulin sensitivity is closely related to both cardiovascular diseases and diabetes development. Still, correlates of insulin sensitivity have mainly been examined in cross-sectional studies. As far as we are aware, the longitudinal stability of insulin sensitivity in young men is largely unknown. We aime...

journal_title：Journal of hypertension

authors： Skårn SN,Flaa A,Kjeldsen SE,Rostrup M,Brunborg C,Reims HM,Fossum E,Høieggen A,Aksnes TA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To investigate whether and how renin-angiotensin inhibition attenuates renal injury seen in salt-induced hypertension in Dahl salt-sensitive (Dahl-S) rats. METHODS:Dahl-S rats fed a high-salt (4% sodium chloride) diet for 6 weeks were treated with the angiotensin converting enzyme (ACE) inhibitor alacepril o...

journal_title：Journal of hypertension

authors： Hirawa N,Uehara Y,Kawabata Y,Ohshima N,Ono H,Nagata T,Gomi T,Ikeda T,Goto A,Yagi S

更新日期：1994-08-01 00:00:00

abstract：OBJECTIVES:Mean blood pressure varies moderately with outdoor air temperature in many western populations. Substantial uncertainty exists, however, about the strength of the relationship in other populations and its relevance to age, adiposity, medical treatment, climate and housing conditions. METHODS:To investigate ...

journal_title：Journal of hypertension

authors： Lewington S,Li L,Sherliker P,Guo Y,Millwood I,Bian Z,Whitlock G,Yang L,Collins R,Chen J,Wu X,Wang S,Hu Y,Jiang L,Yang L,Lacey B,Peto R,Chen Z,China Kadoorie Biobank study collaboration.

更新日期：2012-07-01 00:00:00

abstract：:Reduced nitric oxide bioavailability contributes to endothelial dysfunction and hypertension. The endothelial isoform of nitric oxide synthase (eNOS) is responsible for the production of nitric oxide within the endothelium. Loss of eNOS cofactor tetrahydrobiopterin to initial increase in oxidative stress leads to unco...

journal_title：Journal of hypertension

authors： Li Q,Youn JY,Cai H

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Blood pressure management is a key issue among patients with coronary heart disease (CHD). The present study aimed to identify particular patient groups that may need to be specifically targeted in secondary prevention of CHD. METHODS:EUROASPIRE III is a cross-sectional study conducted in 2006-2007 among pa...

journal_title：Journal of hypertension

authors： Prugger C,Keil U,Wellmann J,de Bacquer D,de Backer G,Ambrosio GB,Reiner Z,Gaita D,Wood D,Kotseva K,Heidrich J,EUROASPIRE III Study Group.

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Vascular and lung function develop and decline over the life course; both predict cardiovascular events and mortality but little is known of how they develop over time. We analysed their relationship in a multiethnic cohort study to test whether lung function from early adolescence to young adulthood affecte...

journal_title：Journal of hypertension

authors： Lu Y,Sooky L,Silva MJ,Molaodi OR,Karamanos A,Cruickshank JK,Harding S

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Prior to the discovery of chloride channel Kb with a variant threonine change to serine at position 481 (CLCNKB-T481S) there were no variants or clinical disorders associated with gain-of-function defects in thick ascending limb of the kidney channels or transporters. CLCNKB-T481S is a novel gain-of-function ...

journal_title：Journal of hypertension

authors： Sile S,Velez DR,Gillani NB,Narsia T,Moore JH,George AL Jr,Vanoye CG,Williams SM

更新日期：2009-02-01 00:00:00

abstract：:A10 vascular smooth muscle cells were placed in a flow chamber and exposed to the circulation of foetal calf serum at different rates and pressures. Under unidirectional laminar flow, physiological flow rates and pressures had almost no effect on internal sodium content. Indeed, pressure values greater than 150 mmHg w...

journal_title：Journal of hypertension

authors： Rosati C,Garay R

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVE:To assess the trends in blood pressure (BP) and in body mass index (BMI) in the hypertensive and normotensive population in Finland during 1982-1997. DESIGN:Four independent cross-sectional standardized population surveys were conducted in 1982, 1987, 1992 and 1997. SETTING:The provinces of North Karelia an...

journal_title：Journal of hypertension

authors： Kastarinen MJ,Nissinen AM,Vartiainen EA,Jousilahti PJ,Korhonen HJ,Puska PM,Tuomilehto

更新日期：2000-03-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to identify, describe, and evaluate the available cardiovascular disease risk prediction models developed or validated in the hypertensive population. METHODS:MEDLINE and the Web of Science were searched from database inception to March 2019, and all reference lists of included arti...

journal_title：Journal of hypertension

authors： Cai R,Wu X,Li C,Chao J

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:To determine the benefits and risks of drinking alcohol in treated hypertensives. DESIGN:A prospective study of 6,369 hypertensives (3,161 men) attending primarily hospital clinics in the UK. METHODS:Relative risks both for drinkers compared with non-drinkers and for level of alcohol consumption were calcul...

journal_title：Journal of hypertension

authors： Palmer AJ,Fletcher AE,Bulpitt CJ,Beevers DG,Coles EC,Ledingham JG,Petrie JC,Webster J,Dollery CT

更新日期：1995-09-01 00:00:00

abstract：OBJECTIVE:Ethnic minority populations (EMPs) are disproportionally affected by hypertension-mediated complications compared with European host populations (EHPs), which might be due to disparities in hypertension awareness, treatment and control. We conducted a systematic review and meta-analysis to compare awareness, ...

journal_title：Journal of hypertension

authors： van der Linden EL,Couwenhoven BN,Beune EJAJ,Daams JG,van den Born BH,Agyemang C

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:The present study aimed to characterize the influence of salt intake on the gene expression of the kidney specific chloride channels CLC-K1 and CLC-K2 in the kidneys of salt-resistant and salt-sensitive Dahl rats. DESIGN:For this purpose Dahl salt-resistant (Dahl-R) and Dahl salt-sensitive rats (Dahl-S) were...

journal_title：Journal of hypertension

authors： Castrop H,Krämer BK,Riegger GA,Kurtz A,Wolf K

更新日期：2000-09-01 00:00:00

abstract：:The activity of renal Na-K-ATPase was compared in hypertension-prone (SBH) and hypertension-resistant (SBN) Sabra rats on regular sodium intake and 2-3 weeks after a high sodium diet. ATPase activity was determined in single nephron segments by a micromethod. The activity profile was found to be similar in the two sub...

journal_title：Journal of hypertension

authors： Doucet A,Mekler J,el Mernissi G,Ben-Ishay D

更新日期：1983-06-01 00:00:00

abstract：OBJECTIVE:To audit the performances of the analytes used in the diagnosis of pheochromocytoma and to present a graphical guideline to help the diagnosis. DESIGN:A 5 year retrospective study. SETTINGS:Laboratory and departments of a university hospital. PARTICIPANTS:In-patients, suspected of bearing a pheochromocytom...

journal_title：Journal of hypertension

authors： Gardet V,Gatta B,Simonnet G,Tabarin A,Chêne G,Ducassou D,Corcuff JB

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:Corticotrophin (ACTH)-induced hypertension in the rat is prevented by L- but not D-arginine. We examined the effects of exogenous corticosterone in the male Sprague Dawley (SD) rat to determine whether ACTH-induced hypertension is mediated by corticosterone. METHODS:Exogenous corticosterone (10, 20 or 40 mg/...

journal_title：Journal of hypertension

authors： Mangos GJ,Turner SW,Fraser TB,Whitworth JA

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:To investigate the role of angiotensin II in the pathogenesis of hyperinsulinemia-induced hypertension in rats. MATERIALS AND METHODS:Chronic hyperinsulinemia was achieved by infusing insulin (3 mU/kg per min) subcutaneously by an osmotic minipump for 6 weeks. An angiotensin converting enzyme inhibitor (fosi...

journal_title：Journal of hypertension

authors： Fang TC,Huang WC

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVE:To evaluate whether efficacious counseling methods on sodium restriction can be successfully incorporated into primary care models for the management of hypertension. METHODS:We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, Database of Abstracts of Reviews of Effects and Health Te...

journal_title：Journal of hypertension

authors： Ruzicka M,Hiremath S,Steiner S,Helis E,Szczotka A,Baker P,Fodor G

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To carry out a population-based evaluation of withdrawal of treatment in primary care using repeated ambulatory blood pressure monitoring (ABPM) assessment to avoid subjecting patients to prolonged periods of excess risk. METHOD:Patients from two community practices (total population 11 034 patients) being a...

journal_title：Journal of hypertension

authors： Prasad N,Davey PG,Watson AD,Peebles L,MacDonald TM

更新日期：1997-12-01 00:00:00

abstract：INTRODUCTION:The effectiveness of renal sympathetic denervation (RDN) as a treatment for therapy-resistant hypertension has been doubted as the Simplicity-HTN-3 trial was unable to show any treatment benefit over sham procedure. This might partly be explained by a high procedural variability in treatment with radiofreq...

journal_title：Journal of hypertension

authors： Fengler K,Höllriegel R,Okon T,Stiermaier T,Rommel KP,Blazek S,Besler C,von Roeder M,Petzold M,Schuler G,Lurz P

更新日期：2017-06-01 00:00:00