Somatosensory auras in refractory temporal lobe epilepsy.

abstract：PURPOSE:To assess the visual system excitability of photosensitive patients with idiopathic generalized epilepsy (IGE) with the paired-pulse flash-evoked potential (paired F-VEP) technique. METHODS:We studied 19 photosensitive patients with IGE (16 women) showing a photoparoxysmal electroencephalographic (EEG) respons...

journal_title：Epilepsia

authors： Strigaro G,Prandi P,Varrasi C,Monaco F,Cantello R

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize the incidence and etiology of temporal lobe epilepsy (TLE) in a community-based cohort of children with new-onset disease. METHODS:A community-based cohort of 30 children with TLE was studied. The patients had new-onset disease before age 14 years between 1995 and 1999...

journal_title：Epilepsia

authors： Sztriha L,Gururaj AK,Bener A,Nork M

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:The standard practice of switching patients to carbamazepine (CBZ) involves initiating a low dose and raising it by small increments until the desired dose is reached, to avoid intolerable adverse effects (AE). In a pilot study, a protocol using single-dose kinetic studies was developed to switch patients to CB...

journal_title：Epilepsia

authors： Kanner AM,Bourgeois BF,Hasegawa H,Hutson P

更新日期：1998-02-01 00:00:00

abstract：:Interictal discharges can occur silently without apparent simultaneous clinical manifestations. Nevertheless, formal testing during electroencephalographic (EEG) recording may demonstrate transitory cognitive impairment (TCI). The probability of demonstrating TCI is related to the nature of the test employed and the t...

journal_title：Epilepsia

authors： Binnie CD,Marston D

更新日期：1992-01-01 00:00:00

abstract：:This essay explores the usefulness of the concept of consciousness in epileptology and concludes that it does not further the understanding of seizure mechanisms and brain function. The reasons for this are both theoretical and empirical. Consciousness cannot be adequately defined. This may explain why attempts at acc...

journal_title：Epilepsia

authors： Gloor P

更新日期：1986-01-01 00:00:00

abstract：:Drug-resistant epilepsy poses a challenge in neonatal patients, especially those in the neonatal intensive care unit (NICU), who have various secondary comorbidities. We present results of four children with a history of drug-resistant epilepsy for whom a ketogenic diet was initiated and used in the NICU. A nonfasting...

journal_title：Epilepsia

authors： Thompson L,Fecske E,Salim M,Hall A

更新日期：2017-02-01 00:00:00

abstract：:The authors report the study of a 30-month-old girl with refractory myoclonic epilepsy associated with mental retardation, growth delay, peculiar facial appearance, and minor physical anomalies. Extensive genetic studies were performed, including an array-based comparative genomic hybridization (array-CGH) that showed...

journal_title：Epilepsia

authors： Veredice C,Bianco F,Contaldo I,Orteschi D,Stefanini MC,Battaglia D,Lettori D,Guzzetta F,Zollino M

更新日期：2009-07-01 00:00:00

abstract：:Treatment with sodium valproate (VPA) in association with phenobarbital (PB) is accompanied by a greater systemic hyperammonemia than treatment by VPA alone. The anatomical origins of this difference were studied by injecting a dose of 1,500 mg VPA i.v. into six unmedicated patients and six epileptics chronically trea...

journal_title：Epilepsia

authors： Warter JM,Marescaux C,Brandt C,Rumbach L,Micheletti G,Chabrier G,Imler M,Kurtz D

更新日期：1983-10-01 00:00:00

abstract：PURPOSE:Traumatic brain injury has long been known to be a cause of epilepsy. Most information on risk factors for developing posttraumatic seizures is from before computed tomography (CT) scanning became universal. This article looks at factors about the injury or individual that put people at especially high risk of ...

journal_title：Epilepsia

authors： Temkin NR

更新日期：2003-01-01 00:00:00

abstract：:Audiogenic seizure-prone mice (DBA/2J) were exposed to a broad band noise source. A reproducible response consisting of wild run, clonus, and tonic stages resulted in all mice. Layers 1 and pyramidal from the parietal cortex and the molecular and Purkinje cell-rich layers from the cerebellar vermis were separately ana...

journal_title：Epilepsia

authors： McCandless DW,Schwartzenburg FC Jr

更新日期：1982-10-01 00:00:00

abstract：PURPOSE:Major depression is a common psychiatric comorbidity in chronic epilepsy that is frequently unrecognized and untreated. A variety of self-report mood inventories are available, but their validity as well as ability to detect major depression in epilepsy remains uncertain. The purpose of this study was to determ...

journal_title：Epilepsia

authors： Jones JE,Hermann BP,Woodard JL,Barry JJ,Gilliam F,Kanner AM,Meador KJ

更新日期：2005-05-01 00:00:00

abstract：:An 8-year-old Chinese girl had a first episode of symptomatic partial epilepsy at age 2 years. Despite regular treatment with antiepileptic drugs (AEDs), the seizures remitted and exacerbated. Epileptiform EEG discharges were evident, arising from the left centroparietal region. Magnetic resonance imaging (MRI) and co...

journal_title：Epilepsia

authors： Wang PJ,Liu HM,Young C,Lin MY,Shen YZ

更新日期：1994-11-01 00:00:00

abstract：:Magnetic resonance spectroscopy (MRS) can be used for noninvasive measurement of more than two dozen small metabolites in the brains of living animals and humans. In the first decade of its use for study of seizure phenomena in animals, MRS successfully detected in vivo seizure-induced cerebral acidosis and reduction ...

journal_title：Epilepsia

authors： Prichard JW

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVE:Corpus callosotomy is an effective palliative treatment for drug-resistant Lennox-Gastaut syndrome (LGS). Laser interstitial thermal therapy has been increasingly used in the treatment of epilepsy. Here, we assess the safety and effectiveness of minimally invasive stereotactic laser anterior corpus callosotom...

journal_title：Epilepsia

authors： Tao JX,Satzer D,Issa NP,Collins J,Wu S,Rose S,Henry J,Santos de Lima F,Nordli D,Warnke PC

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:This study examined the influence of two psychosocial variables mediating between disease severity and quality of life (QoL) in epilepsy; social support and mastery (measured by locus of control and self-efficacy). A model placing these two variables as mediators between disease severity and QoL was tested with...

journal_title：Epilepsia

authors： Amir M,Roziner I,Knoll A,Neufeld MY

更新日期：1999-02-01 00:00:00

abstract：:The antiepileptic drug sodium valproate (VPA) can provoke a thrombocytopenia or platelet dysfunction, with or without hemorrhages. These unwanted side effects are probably infrequent or, at least, have little clinical importance except in patients undergoing surgery. Thromboelastography appears to be a reliable screen...

journal_title：Epilepsia

authors： Loiseau P

更新日期：1981-04-01 00:00:00

abstract：PURPOSE:To evaluate effects of vigabatrin (VGB) by using [123I]iomazenil single-photon emission computed tomography (SPECT) to estimate central gamma-aminobutyric acid (GABA(A))/benzodiazepine receptors (BZRs), and magnetic resonance spectroscopy (MRS) to assess tissue GABA levels. METHODS:Six patients with partial se...

journal_title：Epilepsia

authors： Verhoeff NP,Petroff OA,Hyder F,Zoghbi SS,Fujita M,Rajeevan N,Rothman DL,Seibyl JP,Mattson RH,Innis RB

更新日期：1999-10-01 00:00:00

abstract：PURPOSE:The use of primary health care personnel to identify cases of epilepsy and initiate simple treatment protocols has been advocated as a solution to the numeric inadequacy and uneven distribution of medical manpower available for the management of epilepsy in developing countries. This study sought to evaluate th...

journal_title：Epilepsia

authors： Adamolekun B,Mielke JK,Ball DE

更新日期：1999-04-01 00:00:00

abstract：OBJECTIVE:To assess pharmacokinetics and safety of diazepam nasal spray (NRL-1; VALTOCO®) in pediatric and adult patients with epilepsy in seizure and nonseizure states. METHODS:A single dose of diazepam nasal spray (5, 10, 15, or 20 mg based on weight) was administered during each of two conditions (ictal/peri-ictal ...

journal_title：Epilepsia

authors： Hogan RE,Tarquinio D,Sperling MR,Klein P,Miller I,Segal EB,Rabinowicz AL,Carrazana E

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:The occurrence of psychiatric symptoms after temporal lobectomy is well documented. The aim of the present study was to identify preoperative factors that predict postoperative psychiatric outcome. METHODS:We studied the case notes of 121 patients (from an initial sample of 167) who underwent temporal lobectom...

journal_title：Epilepsia

authors： Anhoury S,Brown RJ,Krishnamoorthy ES,Trimble MR

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Benzodiazepines (BZD) are recommended as first-line treatment for status epilepticus (SE), with lorazepam (LZP) and midazolam (MDZ) being the most widely used drugs and part of current treatment guidelines. Clonazepam (CLZ) is also utilized in many countries; however, there is no systematic comparison of thes...

journal_title：Epilepsia

authors： Alvarez V,Lee JW,Drislane FW,Westover MB,Novy J,Dworetzky BA,Rossetti AO

更新日期：2015-08-01 00:00:00

abstract：:Despite the introduction of newer antiepileptic drugs (AEDs), nonresponsiveness to AEDs remains a common problem in epilepsy clinics. There may be important genetic determinants for responsiveness, and this discussion focused on some potential areas: drug transporters; drug-metabolizing enzymes, and ion channels. We r...

journal_title：Epilepsia

authors： Ramachandran V,Shorvon SD

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:A large number of studies have highlighted the important role of the gut microbiota in the pathophysiology of neurological disorders, suggesting that its manipulation might serve as a treatment strategy. We hypothesized that the gut microbiota participates in absence seizure development and maintenance in the...

journal_title：Epilepsia

authors： Citraro R,Lembo F,De Caro C,Tallarico M,Coretti L,Iannone LF,Leo A,Palumbo D,Cuomo M,Buommino E,Nesci V,Marascio N,Iannone M,Quirino A,Russo R,Calignano A,Constanti A,Russo E,De Sarro G

更新日期：2021-01-11 00:00:00

abstract：:Epilepsy surgery (ES) is addressed in relation to economic classifications of national resources and welfare in developing countries. A decade ago, ten developing countries conducted ES; now 26 such countries have reported results of ES. A number of international authorities define indicators of national economic welf...

journal_title：Epilepsia

authors： Wieser HG,Silfvenius H

更新日期：2000-01-01 00:00:00

abstract：:Study of patients with temporal lobe epilepsy and generalized epilepsy revealed no overall seizure type differences, nor overall age-at-onset effects, on MMPI measures of psychopathology. However, statistically significant interactions between seizure type and age at onset were obtained on several MMPI measures, and s...

journal_title：Epilepsia

authors： Hermann BP,Schwartz MS,Karnes WE,Vahdat P

更新日期：1980-02-01 00:00:00

abstract：PURPOSE:To investigate the risk of illnesses in a cohort of patients with epilepsy and in matched nonepilepsy controls, by type and complications. METHODS:A total of 951 children and adults with idiopathic, cryptogenic, or remote symptomatic epilepsy and 904 matched controls seen in secondary and tertiary centers in e...

journal_title：Epilepsia

authors： van den Broek M,Beghi E,RESt-1 Group.

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:To assess the usefulness of an early postictal EEG in neurologically normal children with complex febrile seizures. METHODS:We conducted a retrospective chart review of all neurologically normal children who were hospitalized over a period of 2.5 years after complex febrile seizures, and had an EEG up to 1 wee...

journal_title：Epilepsia

authors： Maytal J,Steele R,Eviatar L,Novak G

更新日期：2000-02-01 00:00:00

abstract：:Neurogenesis in the adult central nervous system has been well documented in several mammals including humans. By now, a plethora of data has been generated with the aim of understanding the molecular and cellular events governing neurogenesis. This growing comprehension will provide the basis for modulation of neurog...

journal_title：Epilepsia

authors： Rotheneichner P,Marschallinger J,Couillard-Despres S,Aigner L

更新日期：2013-09-01 00:00:00

abstract：:The brain uptake index (BUI) method of Oldendorf was used to examine blood-brain barrier (BBB) drug transport in mice, rats, and rabbits; felbamate (FBM) extraction (E) in a single transcapillary passage was 5-20%, and drug uptake in rat brain was not concentration-dependent. Like diazepam, FBM was retained in mouse b...

journal_title：Epilepsia

authors： Cornford EM,Young D,Paxton JW,Sofia RD

更新日期：1992-09-01 00:00:00

abstract：:Epilepsy is frequently associated with cognitive dysfunction. However, the reasons for this correlation are unclear. Possible influential factors include patient age; duration, frequency, etiology, and type of seizures; hereditary factors; psychosocial issues; and antiepileptic drug (AED) therapy. Whereas many of thes...

journal_title：Epilepsia

authors： Vining EP

更新日期：1987-01-01 00:00:00