Abstract:
OBJECTIVE:Results of many studies show that apolipoprotein B (apo B) is a better marker of risk of vascular disease than other lipid markers including LDL and HDL-cholesterol and triglycerides. We investigated the association between two infectious agents: C. pneumoniae and H. pylori, known to have an atherogenic effect, and apo B, to evaluate the effects of chronic infections on apo B levels. METHODS AND RESULTS:The study group consisted of 257 patients in whom diagnostic coronary angiography was performed. C. pneumoniae IgG and IgM and H. pylori IgG and IgA antibodies were measured by enzyme-linked immunosorbent assay and apo B levels were measured by the nephelometry method. Established risk factors of atherosclerosis were recorded. Of 257 patients recruited, 104 had normal vessels, 88 had 3 or more vessels obstructed and 65 had ectatic vessels without atherosclerosis. Mean apo B concentration was significantly higher in C. pneumoniae IgG and IgM positive healthy subjects compared with C. pneumoniae negatives (0.954 vs. 0.722 and 0.973 vs. 0.851, p < 0.001 and p = 0.007, respectively). Apo B levels were significantly higher in severe atherosclerotic patients (0.985 +/- 0.234 g/l) compared with control subjects (0.892 +/- 0.244 g/l) (p = 0.008), but the difference was not significant in ectatic subjects (0.946 +/- 0.272 g/l) when compared with controls (p = 0.18). Apo B levels were higher but not statistically significant in H. pylori antibody positive cases when compared with negatives. CONCLUSIONS:Apo B levels increased with C. pneumoniae infection. This finding supports the hypothesis that lipid profiles change to atherogenic lipid profile in chronic infections.
journal_name
Acta Cardioljournal_title
Acta cardiologicaauthors
Adiloglu AK,Can R,Kinay O,Aridogan BCdoi
10.2143/AC.60.6.2004930subject
Has Abstractpub_date
2005-12-01 00:00:00pages
599-604issue
6eissn
0001-5385issn
1784-973Xjournal_volume
60pub_type
杂志文章abstract:BACKGROUND:The presence of adhesions after heart operations increases the risk of life-threatening damage to the heart and extracardiac grafts. Infections, tissue injury and inflammations are suspected aetiologic agents. The main purpose of our study is to evaluate the effect of an antiinflammatory agent piroxicam on t...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.6.2024014
更新日期:2007-12-01 00:00:00
abstract::Vasoconstrictory responses to noradrenaline (NA) or high potassium chloride (130 mM) usually show a biphasic behaviour: an initial peak is followed by a lower steady state level. The influence of three beta-sympatholytic agents (propranolol, pindolol, practolol) and a "Ca-antagonist" (verapamil) on this particular beh...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract::The clinical, hemodynamic findings and surgical results of forty patients with rheumatic tricuspid stenosis are presented. It is concluded that tricuspid stenosis is a frequent lesion. Its signs should be sought carefully and documented by simultaneous measurements of the right ventricular diastolic and right atrial p...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVE:The scope of this study is to detect whether or not the entropy (E) circadian rhythm (CR) is maintained preserved in sinusal R-R intervals (SRRI), its loss being the expression of a transition to an indeterministic chaos in heart rate variability (HRV). METHODS:The E of SRRI was estimated in 14 type I diabet...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/ac.62.3.2020814
更新日期:2007-06-01 00:00:00
abstract:OBJECTIVE:Decreased effects of smoking on serum high-density lipoprotein cholesterol (HDL-c) were demonstrated in subjects smoking more than 20 cigarettes a day. We aimed to evaluate the effects of non-heavy smoking (< or =20 cigarettes a day) on HDL-c in young, healthy men who are similar in terms of age, physical act...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.4.2017301
更新日期:2006-08-01 00:00:00
abstract:OBJECTIVES:The primary aim of the study was to investigate whether there is a difference in plasma B-type natriuretic peptide (BNP) levels among the left ventricular systolic dysfunction caused by different types of heart disease. METHODS AND RESULTS:Plasma BNP was measured in patients with left ventricular systolic d...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.3.2005008
更新日期:2005-06-01 00:00:00
abstract:AIM:The aim of this paper is to study the degree of subclinical arterial wall damage in subjects at low and moderate risk of cardiovascular death by the SCORE scale using instrumental research methods. METHODS:We enrolled 600 patients (mean age 49.0 +/- 7.1 years, 74% women) with a calculated SCORE 5%, who passed a ca...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.70.3.3080631
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:High platelet reactivity (HPR) to clopidogrel is associated with an increased risk of ischaemic complications during and after coronary interventions and concerns up to 50% of patients undergoing PCI. AIM OF THE STUDY:The aim of the study was to identify patients with HPR to clopidogrel using bedside clinic...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,多中心研究
doi:10.2143/AC.70.5.3110511
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of this randomized trial was to evaluate whether omission of heparin infusion after successful coronary interventions increased the incidence of ischaemic complications. Continuous heparin infusion after percutaneous coronary interventions could increase the occurrence of bleeding; however, the probab...
journal_title:Acta cardiologica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2143/AC.64.1.2034364
更新日期:2009-02-01 00:00:00
abstract:OBJECTIVE:This study sought to examine the use of treatments at discharge in patients hospitalized for myocardial infarction in a French region. METHODS AND RESULTS:Data from 2,102 patients discharged after myocardial infarction were prospectively collected at 48 university, community, and private hospitals in three d...
journal_title:Acta cardiologica
pub_type: 杂志文章,多中心研究
doi:10.2143/AC.56.1.2005589
更新日期:2001-02-01 00:00:00
abstract::The present study aims at evaluating the acute hemodynamic effects of external and internal (3 and 15 mA) pacing on 30 patients with severe cardiac failure. The global and regional ejection fraction were calculated by repeated radionuclide ventriculography at rest (control) and during increasing pacing rates. Blood pr...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::A case of pulmonary valve endocarditis in a patient with patent ductus arteriosus is reported. The diagnosis was made by echocardiographic examination. The M mode echocardiogram showed "shaggy" echoes on the pulmonic valve and the two dimensional echocardiogram disclosed a big vegetation in the right outflow tract. Th...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:Large pericardial effusions and cardiac tamponade are rare in childhood. The aim of this study was to evaluate the aetiological factors and clinical findings of large pericardial effusion and cardiac tamponade in children. METHODS:We reviewed retrospectively the records of 10 (6 male, 4 female) patients (me...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.62.2.2020232
更新日期:2007-04-01 00:00:00
abstract::Thromboembolic events are major causes of morbidity and mortality in patients with native heart valve disease and artificial heart valves. Oral anticoagulation can reduce these complications. The indication for and intensity of oral anticoagulation depends on both, the risk for thromboembolic events and the risk of he...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::We investigated the effect of an orally administered, long-acting, beta-adrenergic blocking agent, penbutolol, on the circadian rhythm of blood pressure (BP) and heart rate (HR), and plasma renin activity (PRA), aldosterone (PA) and cortisol (PC) levels in hospital patients with essential hypertension validated by a c...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract:OBJECTIVE:Presence of coronary artery disease (CAD) also in subjects without traditional risk factors leads to a search for new risk factors. Tenascin-C (TNC), an extracellular matrix glycoprotein is normally found in very low concentrations in tissues and serum of adults, whereas its expression is enhanced in case of ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.70.6.3120174
更新日期:2015-12-01 00:00:00
abstract::Electroconvulsive therapy (ECT) is used frequently in psychiatric practice and various electrocardiographic (ECG) changes have been described during ECT. QT dispersion (defined as maximal QT interval minus minimal QT interval) as assessed on the surface electrocardiogram has been demonstrated to reflect regional inhom...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Indices of the first derivative and of the normalized first derivative of the left apexcardiogram were used to evaluate the contractile state of the left ventricle of cyclists in the competitive season compared to their resting season and of cardiac patients before and after a physical training program. In both groups...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract:OBJECTIVES:Angiotensin-converting enzyme (ACE) is a key enzyme in the production of angiotensin II and thus may participate in the modulation of cardiac growth. The cloning of the ACE gene has made it possible to identify a deletion (D)-insertion (I) polymorphism that appears to affect the level of serum ACE activity. ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.60.2.2005025
更新日期:2005-04-01 00:00:00
abstract::Background: The presence of intracoronary thrombus is associated with increased ischaemic complications in patients with NSTEMI. High thrombus burden is an independent predictor of major adverse cardiovascular events, stent thrombosis and no reflow in patients with STEMI. CHA2DS2-VASc score predicts thrombus burden in...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2019.1707934
更新日期:2020-01-03 00:00:00
abstract:OBJECTIVES:The role of adenosine as a cardioprotective agent is well known and recent experimental studies suggest that impairment of adenosine-related signal transduction contributes to the pathophysiology of chronic heart failure. The recent observation of an association between ADA, genetic polymorphism and coronary...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/ac.69.1.3011343
更新日期:2014-02-01 00:00:00
abstract::A 57-year-old woman suffering from severe Prinzmetal's angina was treated with a 7-week course of enhanced external counterpulsation (EECP). After completing EECP the angina intensity was reduced from CCS class IV to class I, quality of life was increased and medication was significantly reduced. The number of hospita...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.2.2047066
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:The available literature has not been able to demonstrate the exact association between preoperative statin therapy and the reduction in the rates of major adverse cardiac and cerebrovascular events (MACCE). The aim of this study is to explore these unanswered questions. METHODS:A review of patients having ...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.64.2.2036146
更新日期:2009-04-01 00:00:00
abstract::Endothelial cells release both relaxing and contracting factors that modulate vascular smooth muscle tone and also participate in the pathophysiology of essential hypertension. Endothelium-dependent vasodilation is regulated primarily by nitric oxide but also by an unidentified endothelium-derived hyperpolarizing fact...
journal_title:Acta cardiologica
pub_type: 杂志文章,评审
doi:10.2143/AC.55.4.2005744
更新日期:2000-08-01 00:00:00
abstract::Isolated ventricular noncompaction of myocardium is a rare congenital disease due to an arrest of myocardial morphogenesis during foetal development. It is characterized by a thin compacted epicardial and an extremely thickened endocardial layer with prominent trabeculations and deep intertrabecular recesses. The pers...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.59.2.2005174
更新日期:2004-04-01 00:00:00
abstract:OBJECTIVES:Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) appears to be involved in atherosclerotic plaque vulnerability and rupture. In this study, we aimed to evaluate the utility of serum LOX-1 levels in the diagnosis and assessment of left ventricular systolic HF and LOX-1’s relationship with serum...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.71.2.3141848
更新日期:2016-04-01 00:00:00
abstract:AIM:We aimed to compare the incidence of contrast-induced nephropathy (CIN) between atorvastatin versus rosuvastatin in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary coronary angioplasty. METHODS:One hundred ninety-two consecutive patients, who underwent primary percutaneous inter...
journal_title:Acta cardiologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/ac.68.5.2994472
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure regulation, left ventricular and vascular structure. Some hypertensive patients develop left ventricular dilatation and heart failure symptoms while others are relatively less affected. The purpose of our study was to d...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.61.1.2005137
更新日期:2006-02-01 00:00:00
abstract::A 67-year-old Caucasian woman presented with chest pain suggestive of acute pericarditis. On initial evaluation the apical ballooning variant of stress-related cardiomyopathy (CMP) was present. The stress CMP and acute pericarditis resolved within a week. The patient returned in four weeks with early cardiac tamponade...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.2143/AC.65.3.2050358
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Familial hypercholesterolaemia (FH) is underdiagnosed in most countries. We report our first experience from a national pilot project of cascade screening in relatives of FH patients. METHODOLOGY:Participating specialists recruited consecutive index patients (IP) with Dutch Lipid Clinic Network (DLCN) score...
journal_title:Acta cardiologica
pub_type: 杂志文章
doi:10.1080/00015385.2020.1820683
更新日期:2020-09-23 00:00:00