Abstract:
:Fifteen cases of the sick-sinus syndrome in young Negroes are presented. The etiology was unknown in all cases; organic heart disease was absent. The very high default rate suggests that the prognosis may be grave. This disorder is by no means uncommon in young persons in tropical countries and the dangers of a mistaken diagnosis of epilepsy or a psychiatric illness have been emphasized. In the absence of an artificial pacemaker, it is suggested that sympathomimetic drugs, while not affecting the heart rate, may be useful in reducing the frequency of syncopal attacks.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Ikeme AC,D'Arbela PG,Somers Kdoi
10.1016/0002-8703(75)90078-2subject
Has Abstractpub_date
1975-03-01 00:00:00pages
295-300issue
3eissn
0002-8703issn
1097-6744pii
0002-8703(75)90078-2journal_volume
89pub_type
杂志文章abstract:BACKGROUND:Anemia in heart failure is both common and associated with worse symptoms and increased mortality. Several small randomized controlled trials (RCTs) have assessed erythropoiesis-stimulating agents (ESAs), but definitive evaluation and clinical guidance are required. We sought to systematically review the eff...
journal_title:American heart journal
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ahj.2011.02.013
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Diabetes is associated with a high rate of events after acute coronary syndrome and percutaneous coronary intervention despite aspirin treatment. Once daily aspirin might not provide 24-hour stable biological efficacy in patients with diabetes. We compared the biological efficacy of the same daily dose of as...
journal_title:American heart journal
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ahj.2012.06.008
更新日期:2012-10-01 00:00:00
abstract::Intramuscular lidocaine administration is known to produce blood concentration levels considered to be therapeutic for prevention of premature ventricular contractions. This double blind study was designed to study the effect of intramuscular lidocaine in the prevention of PVC's in acute myocardial infarction. Forty-s...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/s0002-8703(76)80323-7
更新日期:1976-04-01 00:00:00
abstract:BACKGROUND:Recent studies suggest that smokers' coronary endothelial function is impaired because of increased oxidative stress, and their coronary flow velocity reserve (CFVR) is reduced. It is uncertain whether oral antioxidant vitamin C restores impaired CFVR in smokers. Recent technological advances in transthoraci...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.03.006
更新日期:2004-08-01 00:00:00
abstract::The QRS complex and ST segment in the ECGs of 80 patients who died of an acute myocardial infarction (MI) were studied in relation to the extent of the MI (subendocardial vs. transmural). Changes in the QRS complex developed in nine out of the 15 cases with an acute subendocardial MI. Five of these cases fulfilled the...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(79)90219-9
更新日期:1979-08-01 00:00:00
abstract:BACKGROUND:The purpose of this study is to assess incidence and risk factors for severe renal dysfunction in patients requiring oral anticoagulation to help guide initial drug choice and provide a rational basis for interval monitoring of renal function for patients prescribed non-vitamin K oral anticoagulants. METHOD...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2016.08.017
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Troponin level elevations are common in patients with acute decompensated heart failure (ADHF), yet their prognostic value above and beyond traditional predictors of outcomes in heart failure is uncertain. METHODS:In the EFFECT study, we determined the association between cardiac troponin I and all-cause mo...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.01.027
更新日期:2007-04-01 00:00:00
abstract::A double-blind multicenter study compared oral acebutolol (n = 182) with hydrochlorothiazide (n = 178) in the treatment of mild to moderate essential hypertension (diastolic blood pressure 95 to 114 mm Hg). Both agents produced significant and comparable reductions in systolic, diastolic, and mean arterial blood press...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(86)90153-5
更新日期:1986-02-01 00:00:00
abstract::The clinical usefulness of cardiac imaging modalities that rely upon the detection of perfusion defects and wall motion disturbances requires conditions that provoke a heterogeneity of coronary flow and a myocardial oxygen imbalance, respectively. Traditionally, this has been achieved by exercise stress testing. Many ...
journal_title:American heart journal
pub_type: 杂志文章,评审
doi:10.1016/0002-8703(92)90614-2
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND:We evaluate a simple, bedside test that measures 1-minute heart rate variability in deep breathing as a predictor of death after myocardial infarction. METHODS:Bedside heart rate variability was assessed in 185 consecutive patients 5.1 +/- 2.5 days after a first myocardial infarction. Patients were instruct...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(99)70242-5
更新日期:1999-07-01 00:00:00
abstract::Infections related to cardiac surgery increase morbidity and mortality, and increase cost and use of health resources. With the widespread use of synthetic materials, whether in prosthetic valves or vascular conduits, bacterial infection and, more rarely, fungal complications can be devastating, requiring prolonged an...
journal_title:American heart journal
pub_type: 评论
doi:10.1016/j.ahj.2003.08.016
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Data derived from stress myocardial perfusion imaging (MPI) carry prognostic significance in young patients with hypertrophic cardiomyopathy (HCM), but there are limited data on the utility of stress MPI in patients with HCM who are older. This study examined the prognostic significance of stress MPI in an a...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2005.02.050
更新日期:2006-02-01 00:00:00
abstract::We investigated the incidence and mechanism of pulmonary artery hypertension (PAH) in a consecutive series of patients with aortic stenosis who were undergoing diagnostic cardiac catheterization. Forty-five patients with severe aortic stenosis were divided into two groups: group 1 comprised 13 patients (29%) with PAH ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(93)90067-j
更新日期:1993-01-01 00:00:00
abstract::Patients with impaired glucose tolerance (IGT) have increased risk for developing type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle modification and medication can prevent or delay progression to diabetes (PD), but whether such interventions also reduce the risk of CVD has not been rigorously...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2008.05.017
更新日期:2008-10-01 00:00:00
abstract::This case report presents a young adult with asymmetric septal hypertrophy (ASH) and syncope. Infranodal complete heart block was demonstrated as his cause for syncope. Therapy consisted of implantation of a A-V sequential pacemaker. Cardiac output determinations and systolic time intervals demonstrated the beneficial...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/s0002-8703(77)80177-4
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:Fractional flow reserve (FFR) has become a gold standard in physiological assessment of coronary artery stenosis. An FFR < 0.75 is considered as a reliable physiological parameter indicating functionally significant lesion. Lesion length (LL) may affect the translesional hemodynamics. However, the effect of ...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2004.09.007
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Erectile dysfunction (ED) is a common disorder in middle-aged men and is significantly influenced by cardiovascular risk factors (CVRFs) and cardiovascular disease. The substudy of the ONTARGET/TRANSCEND trials evaluates the relationship of erectile function to baseline characteristics and current treatment ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2007.03.024
更新日期:2007-07-01 00:00:00
abstract:AIMS:Furosemide is commonly prescribed for symptom relief in heart failure (HF) patients. Although few data support the continuous use of loop diuretics in apparently euvolemic HF patients with mild symptoms, there is concern about safety of diuretic withdrawal in these patients. The ReBIC-1 trial was designed to evalu...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2017.08.012
更新日期:2017-12-01 00:00:00
abstract::The clinical course and coronary arteriographic findings in eight patients with Prinzmetal's variant angina pectoris are reviewed and contrasted to previously reported cases. In six patients with S-T-elevation inferiorly, three had normal coronary arteriograms, one had complete right coronary artery occlusion, one ha...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(75)90501-3
更新日期:1975-05-01 00:00:00
abstract::The main threat to patients with mild to moderate hypertension is coronary heart disease (CHD), but controlled trials of antihypertensive drug therapy have given disappointing results: overall, the reduction in CHD mortality (11%) and morbidity (10%) were small and nonsignificant. Recent trials comparing a beta blocke...
journal_title:American heart journal
pub_type: 临床试验,杂志文章
doi:10.1016/0002-8703(87)90602-8
更新日期:1987-10-01 00:00:00
abstract:BACKGROUND:Patients with chronic kidney disease (CKD) experience poor outcomes after acute myocardial infarction (AMI). We sought to compare clinical characteristics of advanced CKD, dialysis, and non-CKD patients hospitalized with AMI. METHODS:This observational study used record-linked data from the US Renal Data Sy...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2011.12.002
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The safety and efficacy of ticagrelor in patients with ST-elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remain uncertain. OBJECTIVES:The primary objective of the TicagRElor in pAtients with ST elevation myocardial infarction treated with Thrombolysis (TREAT) trial is to evaluate ...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2018.02.017
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Patients with non-ST-elevation myocardial infarction (NSTEMI) and three-vessel or left main coronary disease (3VD/LMD) have a high risk of long-term mortality when treated with a medical management strategy (MMS) compared with revascularization. METHODS:We evaluated patterns of use and patient features acro...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2013.12.004
更新日期:2014-03-01 00:00:00
abstract::Adenosine infusion is accompanied by increases in coronary blood flow and myocardial blood volume. Myocardial blood volume may produce changes in diastolic left ventricular (LV) performance by increasing myocardial turgor. Diastolic dysfunction may also be the result of myocardial ischemia. The relation between change...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(95)90318-6
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:The impact of valve prosthesis-patient mismatch on long-term outcome after aortic valve replacement estimated by various variables such as projected indexed effective orifice area and internal geometric orifice area obtained from in vivo or in vitro published data is still controversial. METHODS:The effecti...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/j.ahj.2007.12.037
更新日期:2008-06-01 00:00:00
abstract::Even though congestive heart failure is extremely common, the mechanisms responsible for the clinical manifestations remain a puzzle. The central and autonomic (sympathetic) nervous systems are responsible for a large part of the clinical manifestations. The role of the nervous system in CHF is discussed briefly. It i...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(78)90471-4
更新日期:1978-02-01 00:00:00
abstract:BACKGROUND:Myxomas, the most common cardiac tumor in adults, occur in the atria and are prone to embolization. Obstructive valvular tumors in infants occur in pulmonic and aortic valves and generally have a more benign course. METHODS:We conducted a review of our experience in infants with tumors obstructing the right...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1067/mhj.2002.121736
更新日期:2002-05-01 00:00:00
abstract::Pressor response to norepinephrine, cardiopulmonary blood volume, and hemodynamic parameters were studied in 41 borderline hypertensive patients in comparison with 42 permanent essential hypertensive patients and 28 normal subjects. Borderline hypertensive subjects had high cardiac index (p less than 0.0001), normal t...
journal_title:American heart journal
pub_type: 杂志文章
doi:10.1016/0002-8703(75)90155-6
更新日期:1975-04-01 00:00:00
abstract:BACKGROUND:Although sex differences exist in the management of acute coronary syndromes, less is known about the management and outcomes of women and men with suspected coronary artery disease being evaluated with noninvasive testing (NIT). METHODS:We investigated sex-based differences in NIT results and subsequent cl...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ahj.2018.11.002
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:The latest cholesterol guidelines have shifted focus from achieving low-density lipoprotein cholesterol (LDL-C) targets toward statin use and intensity guided by atherosclerotic cardiovascular disease (ASCVD) risk. METHODS:Statin use and intensity were evaluated in 5,905 statin-eligible primary or secondary...
journal_title:American heart journal
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ahj.2017.08.005
更新日期:2017-11-01 00:00:00