Testis structure and function in a nongenetic hyperadipose rat model at prepubertal and adult ages.

abstract：:Transfer of corticosterone from serum to milk was studied in lactating rats after ether and pentobarbital anesthesia. Two minutes after the onset of anesthesia stress, total serum and milk corticosterone concentrations were not significantly different. By 30 min, corticosterone concentrations in serum increased to a p...

journal_title：Endocrinology

authors： Yeh KY

更新日期：1984-10-01 00:00:00

abstract：:Hypoxia-inducible factor-1 (HIF-1) is a decisive element for the transcriptional regulation of many genes expressed in hypoxic conditions. In vascular smooth muscle cells, the vasoactive hormone angiotensin II (Ang II) is a very potent inducer and activator of HIF-1. As opposed to hypoxia, which induces HIF-1alpha by ...

journal_title：Endocrinology

authors： Lauzier MC,Pagé EL,Michaud MD,Richard DE

更新日期：2007-08-01 00:00:00

abstract：:GH and insulin-like growth factor (IGF)-I are important components of the growth axis. We undertook to determine how plasma levels of these hormones altered with different seasonal and nutritional states in young male red deer to provide an insight into how the growth axis changes under these conditions. Growth rate a...

journal_title：Endocrinology

authors： Webster JR,Corson ID,Littlejohn RP,Stuart SK,Suttie JM

更新日期：1996-02-01 00:00:00

abstract：:Retinoic acid (RA), a naturally occurring metabolite of vitamin A, plays an essential role in regulating cellular growth, differentiation, and death in a variety of tissues, particularly during fetal development. However, essentially nothing is known of the effects of RA on fetal gametogenesis. Using a recently valida...

journal_title：Endocrinology

authors： Morita Y,Tilly JL

更新日期：1999-06-01 00:00:00

abstract：:Lactating rats exhibit stable individual differences in pup licking/grooming (LG) over the first week postpartum. Such naturally occurring variations in maternal behavior are associated with differences in estrogen-inducible oxytocin receptors in the medial preoptic area (MPOA) of the hypothalamus. We compared levels ...

journal_title：Endocrinology

authors： Champagne FA,Weaver IC,Diorio J,Sharma S,Meaney MJ

更新日期：2003-11-01 00:00:00

abstract：:To analyze the molecular origin of an ER variant, the truncated ER product-1, transiently expressed at the proestrus in lactotrope cells, we generated a 2.5-kb sequence of a genomic region upstream and downstream the specific sequence truncated ER product-1. Genomic Southern blot analysis showed that truncated ER prod...

journal_title：Endocrinology

authors： Tiffoche C,Vaillant C,Schausi D,Thieulant ML

更新日期：2001-09-01 00:00:00

abstract：:Several studies have shown that insulin-like growth factor-binding proteins (IGF-BPs) modify IGF activity. To investigate their role in regulating growth, the number and size of IGF-BPs in porcine serum and the role of nutritional and endocrine factors in controlling their relative abundance were determined. IGF-BPs w...

journal_title：Endocrinology

authors： McCusker RH,Campion DR,Jones WK,Clemmons DR

更新日期：1989-07-01 00:00:00

abstract：:Uterine contractions at parturition depend upon a variety of factors, including gamma-aminobutyric acid (GABA)-ergic stimulation. A new subunit of the GABA(A) receptor, pi, has recently been identified as being particularly abundant in the rat uterus. Reduced derivatives of progesterone, such as the 3alpha,5alpha-redu...

journal_title：Endocrinology

authors： Fujii E,Mellon SH

更新日期：2001-05-01 00:00:00

abstract：:Experiments were conducted to obtain information on the possible transfer of TSH and thyroid hormones from mother rats to their infants via milk. The mothers were thyroidectomized by surgical or chemical (tapazole) means to eliminate maternal thyroid hormones from milk while increasing its content of TSH. Their pups w...

journal_title：Endocrinology

authors： Glasscock GF,Nicoll CS

更新日期：1983-03-01 00:00:00

abstract：:Term pregnancy human placenta contains hCG/LH receptor mRNA transcripts and immunoreactive receptor protein. Both the receptor transcripts and receptor proteins are present only in trophoblasts. These findings led us to investigate whether hCG can regulate its own synthesis in term pregnancy human placenta. Treatment ...

journal_title：Endocrinology

authors： Licht P,Cao H,Lei ZM,Rao CV,Merz WE

更新日期：1993-12-01 00:00:00

abstract：:Subcutaneous implantation of a silastic tubing containing crystalline estradiol in castrated female rats results in a circadian rhythm of LH release. Under such conditions, blockade of serotonin (5-HT) biosynthesis by p-chlorophenylalanine (PCPA) completely inhibits the afternoon elevation of plasma LH. Gonadotropin p...

journal_title：Endocrinology

authors： Héry M,Laplante E,Kordon C

更新日期：1976-08-01 00:00:00

abstract：:Maternal and fetal metabolism of vitamin D was examined in term pregnant rabbits fed a normal diet and in those supplemented with a large amount of vitamin D3. Term pregnant rabbits (27--30 days of gestation) fed the normal diet showed lower levels of plasma calcium, 25-hydroxyvitamin D3 (250HD3), and 24,25-dihydroxyv...

journal_title：Endocrinology

authors： Kubota M,Ohno J,Shiina Y,Suda T

更新日期：1982-06-01 00:00:00

abstract：:The membrane fraction from the ovaries of pseudopregnant rats exhibits specific, high affinity binding of high density lipoproteins (HDL). Previous studies have indicated that HDL binding in this tissue is up-regulated by hCG and may be involved in supplying cholesterol as substrate for steroid hormone production. To ...

journal_title：Endocrinology

authors： Ferreri K,Menon KM

更新日期：1990-04-01 00:00:00

abstract：:Stanniocalcin (STC) is a new mammalian polypeptide hormone and appears to be a regulator of neuronal function. We have already shown that the induction of STC mRNA and protein expression by cAMP is integral to neuroblastoma cell differentiation, particularly neurite outgrowth. In this study, we examined the cAMP pathw...

journal_title：Endocrinology

authors： Yeung HY,Chan DK,Mak NK,Wagner GF,Wong CK

更新日期：2003-10-01 00:00:00

abstract：:Previous studies showed that epidermal growth factor (EGF) and TGFalpha mimic the action of LH on the resumption of oocyte maturation. We tested whether EGF-like agents, such as amphiregulin (AR), epiregulin (ER), and betacellulin (BTC), also mediate the LH stimulation of the ovulatory response in the rat. LH induced ...

journal_title：Endocrinology

authors： Ashkenazi H,Cao X,Motola S,Popliker M,Conti M,Tsafriri A

更新日期：2005-01-01 00:00:00

abstract：:The pregnane X receptors (PXRs) and the constitutive androstane receptor (CAR) were initially isolated as nuclear receptors regulating xenobiotic metabolism and elimination, alleviating chemical insults. However, recent works suggest that these xenoreceptors play an endobiotic role in modulating hepatic lipid metaboli...

journal_title：Endocrinology

authors： Breuker C,Moreau A,Lakhal L,Tamasi V,Parmentier Y,Meyer U,Maurel P,Lumbroso S,Vilarem MJ,Pascussi JM

更新日期：2010-04-01 00:00:00

abstract：:Mammary glands from second generation vitamin D-deficient mice and rats were examined for their ability to make the major milk proteins, casein and alpha-lactalbumin, both in vivo and in vitro. The glands from the rachitic animals were morphologically indistinguishable from those of age-matched controls. When placed i...

journal_title：Endocrinology

authors： Bhattacharjee M,Wientroub S,Vonderhaar BK

更新日期：1987-09-01 00:00:00

abstract：:A miniature thermoelectric probe was used to record continuously tissue blood flow in the anterior pituitary gland of anesthetized dogs. The output of the flow probe is linear in the range of tissue blood flow encountered in the pituitary. Probe placement required minimal tissue trauma, and zero blood flow was recorde...

journal_title：Endocrinology

authors： Kopaniky DR,Gann DS

更新日期：1975-09-01 00:00:00

abstract：:A healthy nutritional state is required for all aspects of reproduction and is signaled by the adipokine leptin. Leptin acts in a relatively narrow concentration range: too much or too little will compromise fertility. The leptin signal timing is important to prepubertal development in both sexes. In the brain, leptin...

journal_title：Endocrinology

authors： Childs GV,Odle AK,MacNicol MC,MacNicol AM

更新日期：2021-02-01 00:00:00

abstract：:Rat reticulocytes contain a cytosol activator protein (RCAP) that augments hormone-sensitive adenylate cyclase activity in the rat reticulocyte and other systems. In a previous publication, using a highly purified preparation of RCAP, we reported that the stimulatory guanine nucleotide-binding protein (Ns) was require...

journal_title：Endocrinology

authors： Shane E,Yeh M,Feigin AS,Owens JM,Bilezikian JP

更新日期：1985-07-01 00:00:00

abstract：:Diets lacking soy and alpha-alpha derivatives that are considered to be estrogen-free by standard bioassays (uterotrophic assay and vaginal opening) have been revealed to contain considerable amounts of compounds able to transcriptionally activate the estrogen receptors (ERs) and stimulate luciferase expression in sev...

journal_title：Endocrinology

authors： Ciana P,Brena A,Sparaciari P,Bonetti E,Di Lorenzo D,Maggi A

更新日期：2005-12-01 00:00:00

abstract：:The receptors for the two structurally related insulinotropic hormones Glucose-dependent Insulinotropic Polypeptide (GIP) and Glucagon-Like Peptide-1 (GLP-1) share approximately 40% sequence identity and demonstrate complete specificity for their endogenous ligands, while utilizing similar second messenger pathways. I...

journal_title：Endocrinology

authors： Gelling RW,Wheeler MB,Xue J,Gyomorey S,Nian C,Pederson RA,McIntosh CH

更新日期：1997-06-01 00:00:00

abstract：:The aim of this study was to characterize the dynamics and functional relevance of interleukin-1 beta (IL-1 beta)-induced nitric oxide production in isolated pancreatic islets. Thus, islets were isolated from adult rats, precultured for 3-5 days in medium RPMI-1640 plus 10% fetal calf serum, and then exposed to IL-1 b...

journal_title：Endocrinology

authors： Welsh N,Eizirik DL,Bendtzen K,Sandler S

更新日期：1991-12-01 00:00:00

abstract：:Prolonged exposure to elevated glucocorticoid levels is known to produce insulin resistance (IR), a hallmark of diabetes mellitus. Although not fully elucidated, the underlying molecular mechanisms by which glucocorticoids induce IR may provide potential targets for pharmacological interventions. Here we characterized...

journal_title：Endocrinology

authors： Gounarides JS,Korach-André M,Killary K,Argentieri G,Turner O,Laurent D

更新日期：2008-02-01 00:00:00

abstract：:Prolactin (PRL) is an immunomodulatory hormone which promotes T-cell activation and proliferation. However, the intracellular mechanisms of this action in normal lymphocytes are unknown. Because the PRL receptor (PRLR) activates several signals also activated by the T-cell antigen receptor (TCR)/CD3 complex, we evalua...

journal_title：Endocrinology

authors： Montgomery DW,Krumenacker JS,Buckley AR

更新日期：1998-02-01 00:00:00

abstract：:The growth regulatory activity of transforming growth factor-beta 1 (TGF beta 1) was studied in a clonal strain of thyroid papillary carcinoma cell (NPA). Despite the presence of TGF beta 1 and its receptor messenger RNA in thyroid carcinoma, the molecular mechanism of TGF beta 1 action on cell growth of thyroid carci...

journal_title：Endocrinology

authors： Usa T,Tsukazaki T,Namba H,Ohtsuru A,Kimura H,Villadolid MC,Nagataki S,Yamashita S

更新日期：1994-10-01 00:00:00

abstract：:The role of GH during the ovine estrous cycle is unknown. In this study, pituitary GH mRNA and peripheral serum GH levels were measured in ewes representing the major phases of the estrous cycle. There was a significant rise (P less than 0.05) in both GH mRNA and serum GH concentrations during the follicular phase of ...

journal_title：Endocrinology

authors： Landefeld TD,Suttie JM

更新日期：1989-09-01 00:00:00

abstract：:The comparative effectiveness of vitamin D3 and its derivatives in curing hyperparathyroidism and osteodystrophic bone lesions was examined in a laboratory model of renal osteodystrophy associated with marked secondary hyperparathyroidism in rats. The experimental model was prepared by a single injection of homologous...

journal_title：Endocrinology

authors： Fukushima M,Niki R,Ohkawa H,Shimizu T,Matsunaga I,Nakano H,Takagaki Y,Nishii Y,Okano K,Suda T

更新日期：1980-07-01 00:00:00

abstract：:Activin A is a gonadal protein originally isolated from follicular fluid and is recognized as a local regulator of granulosa cell differentiation. Whether activin A promotes folliculogenesis, however, still remains unclarified. The present study was designed to elucidate the effect of activin A on follicular growth in...

journal_title：Endocrinology

authors： Yokota H,Yamada K,Liu X,Kobayashi J,Abe Y,Mizunuma H,Ibuki Y

更新日期：1997-11-01 00:00:00

abstract：:In the present study we examined the mechanisms involved in the activation of the hypothalamo-pituitary-adrenal (HPA) axis after administration of the glucose analog 2-deoxyglucose (2-DG), which inhibits intracellular glucose use. Adult male rats were injected with either 2-DG (400 mg/kg body wt ip) or vehicle and wer...

journal_title：Endocrinology

authors： Weidenfeld J,Corcos AP,Wohlman A,Feldman S

更新日期：1994-04-01 00:00:00