Abstract：
BACKGROUND:Chronic kidney disease (CKD) is associated with an adverse prognosis in patients with coronary heart disease. Cardiac rehabilitation (CR) improves morbidity and mortality among patients with coronary heart disease, but its impact on patients with concomitant CKD has not been described. METHODS:We compared baseline characteristics of patients with CKD (calculated glomerular filtration rate <60 mL/min per 1.73 m2) and without CKD who completed CR between 1996 and 2004 using t tests and chi2 tests. CR outcomes were evaluated by comparing the degree of change in clinical and behavioral variables within and between groups with paired and unpaired t testing, respectively, and by comparing the proportion of patients who achieved secondary prevention goals between groups using chi2 testing. RESULTS:Among 376 patients, CKD was present in 115 (31%). Patients with CKD were older, had more cardiac risk factors and comorbidities, and had lower functional capacity and perceived health status than patients without CKD. Both groups achieved significant improvements in diet scores, body weight, lipid profiles, 6-minute walk distances, physical activity level, and perceived health status. The proportion of patients who achieved secondary prevention goals was also similar, but patients with CKD continued to have lower high-density lipoprotein cholesterol, lower physical component health status summary scores, and lower functional capacity than patients without CKD. CONCLUSIONS:CKD is common among CR participants. Patients with CKD have a high cardiovascular risk factor and comorbidity burden. CR is as effective in improving coronary risk profiles among patients with CKD as it is among patients with normal renal function.
journal_name
Am Heart Jjournal_title
American heart journalauthors
Venkataraman R,Sanderson B,Bittner Vdoi
10.1016/j.ahj.2005.01.048subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1140-6issue
6eissn
0002-8703issn
1097-6744pii
S0002-8703(05)00117-1journal_volume
150pub_type
杂志文章abstract：:Atherosclerosis and its vascular sequela are responsible for considerable morbidity and mortality rates. Several risk factors have been implicated in the pathogenesis of atherosclerosis, and the search for other risk factors continues on the medical horizon. Renin-angiotensin system (RAS), a multienzyme, multilocale a...
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1016/s0002-8703(97)70089-9
更新日期：1997-09-01 00:00:00
abstract：:A new integrated method for quantitating temporal and spatial systolic wall motion heterogeneity was developed and applied in 15 normal subjects and 26 patients with previous myocardial infarction (MI). After frame by frame digitizing, right anterior oblique left cineventriculograms (LV) were analyzed with 90 spaced r...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(86)90465-5
更新日期：1986-10-01 00:00:00
abstract：:A total of 127 patients with chronic heart failure referred to our exercise laboratory were studied retrospectively to identify parameters predictive of prognosis. Patients were followed for a mean of 14.6 months. The group as a whole had severe ventricular dysfunction with a median ejection fraction of 17% and a medi...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(92)90656-g
更新日期：1992-02-01 00:00:00
abstract：BACKGROUND:Although the use of clopidogrel in patients "unlikely" to require coronary artery bypass grafting (CABG) is recommended in current guidelines of acute coronary syndrome (ACS) management, an important minority of patients require CABG. We assessed the ability to predict need for CABG from demographics known a...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2007.12.002
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND:In the setting of ST-segment elevation myocardial infarction, timely restoration of normal blood flow is associated with improved myocardial salvage and survival. Despite improvements in door-to-needle and door-to-balloon times, there remains an unmet need with respect to improved symptom-to-door times. A pr...
journal_title：American heart journal
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.ahj.2014.05.010
更新日期：2014-10-01 00:00:00
abstract：BACKGROUND:Little is known about the role of diet in the development of venous thromboembolism (VTE). We explored the prospective relation of dietary patterns, food groups, and nutrients to incident VTE in older women. METHODS:In 1986, Iowa women aged 55 to 69 years completed a mailed survey, including a 127-item food...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2009.04.003
更新日期：2009-06-01 00:00:00
abstract：:Major cardiovascular risk factors, such as hypertension, hyperlipidemia, and diabetes, often cluster in the same individuals. It has been claimed that obesity, hyperinsulinemia, insulin resistance, and a deranged intracellular handling of ions have pathogenetic importance in the development of this metabolic syndrome....
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1016/0002-8703(93)90446-g
更新日期：1993-05-01 00:00:00
abstract：:The effects of alcohol intake on serum lipids and lipoproteins depend on the dose and mode of alcohol intake, individual susceptibility, genetic variables, and dietary factors. Therefore the changes of lipoprotein pattern are different among moderate and heavy drinkers. Moderate intake of alcohol increases the concent...
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1016/0002-8703(87)90614-4
更新日期：1987-02-01 00:00:00
abstract：BACKGROUND:Studies on the effect of heart failure clinics have been encouraging and convincing with respect to reduced hospitalizations, improved quality of life, and reduced cost. However, previous results have been derived from patient populations either recently discharged and with specific exclusion criteria or fro...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1067/mhj.2002.123841
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:Analyses of country or regional differences in cardiovascular (CV) trials are based on geographical subgroup analyses. However, apart from map location and related racial, ethnic, and genetic variations, identified differences may also depend on social structure and provision and access to health care, for w...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2019.08.019
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Endothelial progenitor cells (EPCs) are present in peripheral blood and can promote postnatal angiogenesis. The number and function of circulating EPCs are altered in diabetics. This study sought to investigate whether the number and functional properties of EPCs from patients with type II diabetes could be ...
journal_title：American heart journal
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ahj.2006.07.029
更新日期：2006-12-01 00:00:00
abstract：:Left circumflex coronary blood flow was increased significantly (20 per cent) during stimulation of somatic afferent fibers. The change in CBF was associated with significant increases in heart rate and arterial pressure and significant decrease in coronary vascular resistance. Controlling heart rate or preventing car...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(79)90318-1
更新日期：1979-07-01 00:00:00
abstract：:Controlled-release drug delivery technology has had a significant effect on the pharmacotherapy of cardiovascular diseases. Oral and transcutaneous controlled-release systems allow relatively short-acting drugs to be administered once or twice daily with comparable therapeutic efficacy and fewer adverse reactions comp...
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1016/0002-8703(95)90019-5
更新日期：1995-02-01 00:00:00
abstract：:To determine whether a dose of 5 mg of nifedipine would be useful in the treatment of hypertensive emergencies, we compared the acute hypotensive effects of two different doses of nifedipine, 5 mg and 10 mg, in patients with severe hypertension. In this prospective, randomized, double-blind study, 30 consecutive black...
journal_title：American heart journal
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0002-8703(92)90283-2
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:Previous studies have demonstrated that the adenosine monophosphate deaminase 1 (AMPD1) C34T polymorphism may be associated with survival in cardiac populations with a protective effect of the T allele. However, these studies included limited number of patients with few cardiovascular events. METHODS:We pro...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2006.04.003
更新日期：2006-10-01 00:00:00
abstract：BACKGROUND:Previous research suggests that after coronary artery bypass graft (CABG) surgery, women fare worse than men. This study investigates sex differences in depression during recovery from CABG surgery. METHODS:We followed 137 patients (72 men, 65 women) undergoing elective isolated first CABG surgery between J...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2005.05.005
更新日期：2005-11-01 00:00:00
abstract：OBJECTIVE:To assess whether serum uric acid, which is a marker of impaired oxidative metabolism, might correlate with left ventricular systolic and diastolic dysfunction in patients with chronic heart failure (CHF). BACKGROUND:Uric acid levels, which are frequently elevated in patients with CHF, correlate with leg vas...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1067/mhj.2002.122122
更新日期：2002-06-01 00:00:00
abstract：:Intramuscular lidocaine administration is known to produce blood concentration levels considered to be therapeutic for prevention of premature ventricular contractions. This double blind study was designed to study the effect of intramuscular lidocaine in the prevention of PVC's in acute myocardial infarction. Forty-s...
journal_title：American heart journal
pub_type： 临床试验,杂志文章
doi：10.1016/s0002-8703(76)80323-7
更新日期：1976-04-01 00:00:00
abstract：BACKGROUND:The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI). METHODS AND RESULTS:Two hundred sixty-two patients with acute chest pain and suspected AMI were randomly assigned b...
journal_title：American heart journal
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0002-8703(99)70405-9
更新日期：1999-05-01 00:00:00
abstract：:Although cost estimates for acute myocardial infarction are necessary for decisions about allocating scarce resources, there is a relative paucity of studies that estimate these costs across the entire spectrum of hospitals in actual clinical practice. This study sought to determine the correlates of in-hospital costs...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/s0002-8703(98)70331-x
更新日期：1998-03-01 00:00:00
abstract：:Major depression is a common comorbidity associated with ischemic heart disease (IHD). There is growing evidence that psychological stress in general and depression in particular predispose to cardiovascular disease. Persons who have mental stress during daily life are at twice the risk of myocardial ischemia, and pat...
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1067/mhj.2000.109979
更新日期：2000-10-01 00:00:00
abstract：:The associations between socioeconomic status, ethnic origin, and risk factors for CHD were studied in 2,591 white and black children from two socioeconomically dissimilar populations in the New York City area. The study subjects were selected from all fourth graders in 44 elementary schools. Blood pressure, plasma li...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(87)90724-1
更新日期：1987-03-01 00:00:00
abstract：BACKGROUND:Recent studies suggest that smokers' coronary endothelial function is impaired because of increased oxidative stress, and their coronary flow velocity reserve (CFVR) is reduced. It is uncertain whether oral antioxidant vitamin C restores impaired CFVR in smokers. Recent technological advances in transthoraci...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2004.03.006
更新日期：2004-08-01 00:00:00
abstract：:High degree AV block occurred in 144 of 843 patients consecutively admitted because of acute inferior myocardial infarction and was associated with more extensive myocardial damage and a higher mortality rate, as compared to those without AV block. Patients with power failure at the time of appearance of high degree A...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(80)90308-7
更新日期：1980-01-01 00:00:00
abstract：BACKGROUND:Myxomas, the most common cardiac tumor in adults, occur in the atria and are prone to embolization. Obstructive valvular tumors in infants occur in pulmonic and aortic valves and generally have a more benign course. METHODS:We conducted a review of our experience in infants with tumors obstructing the right...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1067/mhj.2002.121736
更新日期：2002-05-01 00:00:00
abstract：:A morphologic study of 466 cardiac mural thrombi, 66 examples of nonbacterial thrombotic endocarditis, 25 myxomas, and 12 papillary endocardial lesions was performed. It appeared that three different sequences of organization of endocardial thrombi are possible. (1) Ordinary mural thrombi are converted into a flat, fi...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(75)90003-4
更新日期：1975-01-01 00:00:00
abstract：:To understand the process of atherosclerosis, the homeostatic and protective functions of the endothelium must be considered. The endothelium serves as the interface between blood flow and the vascular tissues. It normally regulates vascular tone and structure through the release of vasoactive substances and maintenan...
journal_title：American heart journal
pub_type： 杂志文章,评审
doi：10.1016/0002-8703(94)90251-8
更新日期：1994-12-01 00:00:00
abstract：OBJECTIVES:SUPPORT-HF 2 tests the hypothesis that home monitoring with information technology-supported specialist management is more effective in optimizing medical therapy than is home monitoring alone for patients with heart failure. METHODS AND RESULTS:The study was designed as a 2-armed partially blinded parallel...
journal_title：American heart journal
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1016/j.ahj.2018.09.007
更新日期：2019-02-01 00:00:00
abstract：:Flow beyond a stenotic aortic valve (AS) is dynamically complex. Numerous hydraulic studies have demonstrated that at least four well-known major flow areas occur distal to a stenotic valve. These include a jet, an area alongside the jet (the parajet), an area of flow disturbance, and an area in which disturbed flow a...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/0002-8703(82)90400-8
更新日期：1982-05-01 00:00:00
abstract：BACKGROUND:Heart failure still maintains a high mortality. Biomarkers reflecting different pathophysiological pathways are under evaluation to better stratify the mortality risk. The objective was to assess high-sensitivity cardiac troponin T (hs-cTnT) in combination with N-terminal pro-B type natriuretic peptide (NT-p...
journal_title：American heart journal
pub_type： 杂志文章
doi：10.1016/j.ahj.2012.03.004
更新日期：2012-05-01 00:00:00
