Abstract:
:The concept of the "vulnerable" plaque has recently emerged to explain how quiescent atherosclerotic lesions evolve to cause clinical events. The morphologic and immunologic determinants specific for the vulnerable plaque have been reported: a large lipid core (>or=40% plaque volume) composed of free cholesterol crystals, cholesterol esters, and oxidized lipids impregnated with tissue factor; a thin fibrous cap depleted of smooth muscle cells and collagen; an outward (positive) remodeling; inflammatory cell infiltration of fibrous cap and adventitia (mostly monocyte-macrophages, some activated T cells, and mast cells); and increased neovascularity. Despite the large amount of information regarding the morphological characteristics of remote lesions, we lack studies with functional assessment of non-culprit lesions. Coronary thermography is a technique for functional assessment of coronary atherosclerotic plaques. Several catheter designs have been proposed. There are catheters with thermistor(s) and wires with thermal sensors at the distal tip. All designs have several advantages and disadvantages. Despite the current limitations of coronary thermography, we gained important pathophysiological and clinical information regarding the vulnerability of atheromatic plaques. It has been documented both experimentally and clinically that increased heat generation is associated with increased macrophage concentration within the plaque. The correlation between local inflammatory involvement and local heat generation has also been observed with the peripheral inflammatory markers such as C-reactive protein. Whether systemic treatment, with agents such as statins or interventional techniques, such as drug-eluting stents, will have an impact on stabilizing vulnerable plaques need to be determined in future studies. In conclusion, although there are several techniques for evaluating morphologically atheromatic plaques, thermography is a promising method for the functional assessment of vulnerable plaque and has been introduced into clinical practice, with a good predictive value for clinical events in patients with increased temperature in the atherosclerotic plaque.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Toutouzas K,Drakopoulou M,Stefanadi E,Siasos G,Stefanadis Cdoi
10.1111/j.1540-8183.2005.00090.xsubject
Has Abstractpub_date
2005-12-01 00:00:00pages
485-9issue
6eissn
0896-4327issn
1540-8183pii
JOIC090journal_volume
18pub_type
杂志文章,评审abstract::We discuss the case of a 61-year-old male patient with hypertrophic cardiomyopathy and chest pain on exertion. Coronary angiography and intravascular ultrasound revealed an intermediate stenosis in the proximal site of the left anterior descending artery, while Tc-99m myocardial scintigraphy revealed exercise-induced ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01029.x
更新日期:2002-02-01 00:00:00
abstract:OBJECTIVES:The authors investigated safety and efficacy of the MitraClip-System (MCS) using a systematic analysis. BACKGROUND:The safety and efficacy of the MCS continues to be debated, and randomized trials are still lacking. METHOD:A systematic literature search was conducted using common medical and scientific dat...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/joic.12168
更新日期:2015-02-01 00:00:00
abstract::We describe a patient with an intracardiac intravenous catheter fragment in the right heart that was found during fluoroscopy. The catheter fragment had broken off from an intravenous catheter inserted 25 years previously when the patient was admitted after a road accident. There were no complications during these yea...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01080.x
更新日期:2002-10-01 00:00:00
abstract:Background:Urinary kidney injury molecule 1 (uKIM-1) is a proximal tubular injury biomarker for predicting acute kidney injury (AKI); its prognostic value varies depending on the clinical and population characteristics. However, the predictive value of uKIM-1 for diagnosis of contrast-induced acute kidney injury (CI-AK...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,meta分析
doi:10.1155/2020/4982987
更新日期:2020-08-13 00:00:00
abstract::Atrial septal defect (ASD) is a common diagnosis in young adults with congenital heart disease. The aim of this study was to determine if ocular symptoms following percutaneous treatment are due to microemboli. The study group included 20 adult patients (9 men, 11 women, mean age 57.2 years) with ASD who had undergone...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2005.00392.x
更新日期:2005-02-01 00:00:00
abstract::In an effort to keep the interventional community up-to-date with the abundant amount of new data, we have selected what we believe to be the most important publications in percutaneous coronary intervention from January 1, 2017 to December 2017. ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/joic.12508
更新日期:2018-04-01 00:00:00
abstract::Transcatheter aortic valve replacement (TAVR) has emerged as an attractive option for patients with severe symptomatic aortic stenosis (AS) who are either at high risk or extreme risk for surgical aortic valve replacement (SAVR). This article summarizes the major advances in TAVR that were published or reported in 201...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/joic.12274
更新日期:2016-02-01 00:00:00
abstract::This case report documents the presentation of a disabling ionizing radiation (IR)-related illness (multiple basal cell carcinoma [BCC] syndrome) in a 50-year-old interventional cardiologist. This case emphasizes the need for interventionalists to: (1) understand the occupational hazards of IR; (2) recognize the failu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00610.x
更新日期:2011-02-01 00:00:00
abstract::Implantable cardioverter defibrillators are devices capable of detecting and terminating ventricular tachycardias or fibrillations. They are utilized in the treatment of severe ventricular tachyarrhythmias, and their efficacy in the prevention of sudden death is demonstrated. As a matter of fact, despite the new antia...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.1995.tb00931.x
更新日期:1995-12-01 00:00:00
abstract:AIMS:To evaluate the correlation between iFR and FFR in real-world clinical practice. METHODS AND RESULTS:Retrospective, single-centre study of 229 consecutive pressure-wire studies (np = 158). Real-time iFR and FFR measurements were performed for angiographically borderline stenoses. Functionally significant stenose...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12422
更新日期:2017-12-01 00:00:00
abstract:Background:Transcatheter aortic valve implantation (TAVI) is currently recommended for patients with severe aortic stenosis at intermediate or high surgical risk. The decision process during TAVI evaluation includes a thorough benefit-risk assessment, and knowledge about long-term benefits and outcomes may improve pati...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2019/4292987
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Stent thrombosis is a major complication after percutaneous coronary intervention (PCI) for ST-segment elevation acute myocardial infarction (AMI) and is associated with reinfarction and increased risk of death. METHODS:Patients treated with the turbostratic carbon-coated stent (CID, Saluggia, Italy) for AM...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00564.x
更新日期:2010-12-01 00:00:00
abstract:OBJECTIVES:The present study assesses clinical outcomes in patients from the Potential Angina Class Improvement From Intramyocardial Channels (PACIFIC) trial of percutaneous transmyocardial revascularization (PTMR) who had previously been considered "no-option," but who subsequently underwent percutaneous coronary inte...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2004.00325.x
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:Left main coronary artery (LMCA) disease is associated with significant cardiovascular mortality. The data on patient characteristics' predicting outcomes after LMCA revascularization is sparse. METHODS:A retrospective study of 227 patients with LMCA disease documented on coronary angiography from March 200...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2013.12012.x
更新日期:2013-02-01 00:00:00
abstract::Alcohol septal ablation is increasingly being offered as a therapy for patients with hypertrophic obstructive cardiomyopathy. The procedure is most often performed in stable patients with a history of increasing symptoms. We describe a patient with hypertrophic obstructive cardiomyopathy with an acute decompensation s...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2005.00069.x
更新日期:2005-10-01 00:00:00
abstract::A group of 312 patients who underwent percutaneous coronary intervention for bifurcation lesions at 12 centers in China, Singapore, Thailand, Israel, India, and Japan were enrolled in a prospective, randomized DKCRUSH-1 trial. The goal of the study was to compare the double kissing (DK) crush technique with the classi...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/j.1540-8183.2009.00440.x
更新日期:2009-04-01 00:00:00
abstract::Four different types of occluder systems were used to close a persistent foramen ovale (PFO) in 162 patients with paradoxical embolic events. Ninety-eight patients had ischemic stroke, 60 transient ischemic attacks (TIA) or prolonged reversible ischemic neurological deficit (PRIND), and 4 had peripheral arterial embol...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2001.tb00740.x
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:We investigated and compared the clinical outcomes between biodegradable polymer biolimus-eluting stents (BES) and durable polymer everolimus-eluting stents (EES) in a single-center prospective registry. BACKGROUND:There is limited data regarding the safety and efficacy of the biodegradable BES compared to ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12140
更新日期:2014-08-01 00:00:00
abstract::Forty patients undergoing percutaneous transluminal coronary angioplasty (PTCA) with severely impaired left ventricular ejection fraction (LVEF) < 30% were randomized between prophylactic intraaortic balloon pump (IABP) support (N = 20) and percutaneous cardiopulmonary bypass (PCPB) support (N = 20). The indications f...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1540-8183.1995.tb00532.x
更新日期:1995-04-01 00:00:00
abstract:Objective:The aim of this study was to compare feasibility, effectiveness, safety, and outcome of atrial septal defect (ASD) device closure in children with and without fluoroscopy guidance. Methods and Results:Children undergoing transcatheter ASD closure between 2002 and 2016 were included into this single center, r...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2019/6598637
更新日期:2019-04-07 00:00:00
abstract:OBJECTIVE:To compare the safety and efficacy of transcathether aortic valve-in-valve implantation (ViV-TAVI) in degenerated stentless bioprostheses with failed stented valves and degenerated native aortic valves. INTRODUCTION:Little is known about ViV-TAVI in degenerated stentless valves. METHODS:Out of 45 ViV-TAVI p...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12540
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:Study the new Amplatzer Duct Occluder II (ADO II). Limitations were encountered with the preexisting devices in nonconical ducts, large ducts, or in small infants. These include failure, residual shunts, protrusion, migration, and vascular damage. METHODS:Between June 2008 and March 2009, 20 consecutive pati...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00504.x
更新日期:2009-12-01 00:00:00
abstract::Drug-eluting stents have altered the practice of interventional cardiology by dramatically reducing the risk of angiographic and clinical restenosis following percutaneous coronary intervention. Based on extensive preclinical study and clinical trial data, the polymer-based, slow rate-release paclitaxel-eluting TAXUS ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2004.04040.x
更新日期:2004-10-01 00:00:00
abstract:OBJECTIVE:This study sought to identify patient and left atrial morphology specific factors associated with early complications for left atrial appendage occlusion with the Watchman™ (Boston Scientific, Natick, MA) device. BACKGROUND:Oral anticoagulation (OAC) is recommended for patients with atrial fibrillation, howe...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12374
更新日期:2017-04-01 00:00:00
abstract::The purpose of this study is to evaluate long-term clinical and angiographic follow-up results after placement of the Palmaz-Schatz stent and angiographic follow-up results of repeat interventions for stent restenosis. From June 1990 to September 1993, the Palmaz-Schatz stent was placed in 411 patients, 427 lesions. ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.1994.tb00896.x
更新日期:1994-04-01 00:00:00
abstract:Objectives:We aimed to identify mechanical and pharmacological revascularization strategies correlated with the index of microcirculatory resistance (IMR) in ST-elevation myocardial infarction (STEMI) patients. Background:Microvascular dysfunction (MVD) after STEMI is correlated with infarct size and poor long-term pr...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2020/5036396
更新日期:2020-07-09 00:00:00
abstract:BACKGROUND:Drug-eluting stents showed a better angiographic and clinical outcome in comparison with bare metal stent in chronic total occlusions (CTOs) percutaneous revascularization, however, great concerns still remain regarding the rate of restenosis and reocclusion in comparison with nonocclusive lesions. AIM:To e...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00648.x
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:These days no codified multidisciplinary protocol has been reported to manage all the different patent foramen ovale (PFO)-mediated syndromes. We sought to propose a multidisciplinary program of diagnosis, treatment, and follow-up of all PFO-mediated syndromes based on an in-hospital multidisciplinary task f...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00141.x
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:To compare the effectiveness and safety of balloon aortic valvuloplasty (BAV) performed with or without rapid ventricular pacing (RP). BACKGROUND:BAV technique is poorly standardized. METHODS:One hundred consecutive patients were randomly assigned 1:1 between BAV performed with or without RP. Exclusion cri...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1111/joic.12452
更新日期:2018-02-01 00:00:00
abstract:OBJECTIVES:To prospectively compare the impact of ultrathin-strut cobalt-chromium (Cro-Co) bare metal stent (BMS) versus thin-strut stainless steel (SS) BMS on clinically driven target lesion revascularization (TLR). BACKGROUND:Stent characteristics are an important determinant of restenosis. Thinner strut Cro-Co BMS ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12300
更新日期:2016-06-01 00:00:00