Abstract:
OBJECTIVES:The authors investigated safety and efficacy of the MitraClip-System (MCS) using a systematic analysis. BACKGROUND:The safety and efficacy of the MCS continues to be debated, and randomized trials are still lacking. METHOD:A systematic literature search was conducted using common medical and scientific databases. The following kinds of data were obtained: at baseline, 30 days, 6 and 12 month post-procedure. For safety and efficacy mortality-rate (survival), mitral regurgitation <2+ (MR), adverse event rate (AE), NYHA class and reoperation-rate were documented. A meta-analysis with quantitative summary was performed. RESULTS:Twenty-six studies including 3821 patient's who were treated with MCS, were analyzed. Weighted mean age was 73.9 ± 2.3 years and LogEuroScore was 25.2 ± 6.0%. Post-procedural MR<2+ was achieved in 86.4% and 66.3% of the patients were in NYHA class I/II within 30 days, AE-rate was 18.3%, mortality-rate was 2.8% and reoperation-rate was 3.5%. Freedom from MR>3 + -4 was 80.2% (80.1%), from NYHA III/IV was 78.6% (66.1%) and freedom from death was 82.6% (87.8%) and from reoperation 95.6% (88.6%) at 6 and 12 month. CONCLUSION:Based on the analysis of the current literature treatment with MCS is associated with good short-term success and low mortality. MCS is safe and effective for patients with limited surgical options. The results are comparable with open mitral valve repair (oMVR) but patients are markedly older and have a higer risk profile than patients who undergo oMVR. Prospective randomized controlled trials are warranted to determine potential AEs, device durability and long-term follow-up.
journal_name
J Interv Cardioljournal_title
Journal of interventional cardiologyauthors
Bail DHdoi
10.1111/joic.12168subject
Has Abstractpub_date
2015-02-01 00:00:00pages
69-75issue
1eissn
0896-4327issn
1540-8183journal_volume
28pub_type
杂志文章,meta分析,评审abstract::This case report documents the presentation of a disabling ionizing radiation (IR)-related illness (multiple basal cell carcinoma [BCC] syndrome) in a 50-year-old interventional cardiologist. This case emphasizes the need for interventionalists to: (1) understand the occupational hazards of IR; (2) recognize the failu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00610.x
更新日期:2011-02-01 00:00:00
abstract::Local delivery of immunosuppressive or antiproliferative agents using a drug-eluting stent is a new technology that is supposed to inhibit in-stent restenosis, thus providing a biological and mechanical solution. This technique is a very promising. To date, several agents have been used, including paclitaxel, QP-2, ra...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01091.x
更新日期:2002-12-01 00:00:00
abstract:BACKGROUND:Multiple randomized trials and observational studies have shown drug-eluting stents (DES) to be safe and effective at 3-year follow-up in stent thrombosis (ST)-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI). However, outcomes data beyond 3-4 year...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00703.x
更新日期:2012-04-01 00:00:00
abstract::The consistent message that emerges from virtually every recent acute coronary syndrome (ACS) trial is that the old "standard" of using aspirin and unfractionated heparin (UFH) can be considerably improved upon. Low molecular weight heparins (LMWHs) (most notably enoxaparin) are emerging as a broad replacement for UFH...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2002.tb01047.x
更新日期:2002-04-01 00:00:00
abstract::Transradial coronary angiography (TRC) can be performed applying only one catheter fitting into the right and left coronary ostia (R/LCO). In this bicentric study (n = 2953), we analyzed the ostial performance of the Tiger_II_catheter widely used in TRC. Compared to Judkins catheters, the Tiger_II is frequently associ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12266
更新日期:2016-02-01 00:00:00
abstract:OBJECTIVE:Study the new Amplatzer Duct Occluder II (ADO II). Limitations were encountered with the preexisting devices in nonconical ducts, large ducts, or in small infants. These include failure, residual shunts, protrusion, migration, and vascular damage. METHODS:Between June 2008 and March 2009, 20 consecutive pati...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00504.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Drug-eluting stents showed a better angiographic and clinical outcome in comparison with bare metal stent in chronic total occlusions (CTOs) percutaneous revascularization, however, great concerns still remain regarding the rate of restenosis and reocclusion in comparison with nonocclusive lesions. AIM:To e...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00648.x
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Postdilatation (PD) with noncompliant balloon during elective percutaneous coronary intervention (PCI) is performed usually in clinical practice in order to optimize stent expansion. However, current knowledge about its use in patients undergoing primary PCI is controversial. This study aims to evaluate the ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12041
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:Our aim was to establish the frequency of arterial anatomic variations and its relation to coronary procedural outcome in patients undergoing a first transradial coronary procedure. METHODS:This was a single center prospective study. A total of 1,446 consecutive patients undergoing their first transradial c...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2012.00693.x
更新日期:2012-08-01 00:00:00
abstract::A 67-year-old male with prior history of myocardial infarction and coronary artery bypass grafting (individual vein grafts to the left anterior descending artery [LAD] and right coronary artery) presented with an acute anterior ST elevation myocardial infarction and cardiogenic shock. The vein graft to the LAD was occ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00129.x
更新日期:2006-04-01 00:00:00
abstract:Objectives:We aimed to identify mechanical and pharmacological revascularization strategies correlated with the index of microcirculatory resistance (IMR) in ST-elevation myocardial infarction (STEMI) patients. Background:Microvascular dysfunction (MVD) after STEMI is correlated with infarct size and poor long-term pr...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1155/2020/5036396
更新日期:2020-07-09 00:00:00
abstract:AIMS:To evaluate the correlation between iFR and FFR in real-world clinical practice. METHODS AND RESULTS:Retrospective, single-centre study of 229 consecutive pressure-wire studies (np = 158). Real-time iFR and FFR measurements were performed for angiographically borderline stenoses. Functionally significant stenose...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12422
更新日期:2017-12-01 00:00:00
abstract::The reliability, rapidity, and safety of nonsurgical, transatrial pericardial access for local cardiac therapy have been demonstrated in healthy animals. Since many patients take aspirin or have increased right-sided pressures, we evaluated the procedure's safety under these conditions. Transatrial pericardial access ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2001.tb00364.x
更新日期:2001-10-01 00:00:00
abstract::Excimer lasers are being extensively used for coronary angioplasty along with multifiber over-the-wire catheters. To determine whether another wavelength could be an alternative, the laser-tissue interaction and the clinical usefulness of an infrared laser were studied. The laser consisted of a Holmium YAG pulsed la...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.1991.tb00790.x
更新日期:1991-01-01 00:00:00
abstract::Direct stenting could potentially lead to a reduction in dissections, time, and restenosis at 6-month follow-up. Using the premounted Palmaz-Schatz Crown stent elective stenting was performed without predilatation in 61 consecutive patients who were compared with a control group of provisional stenting. All patients u...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2002.tb01101.x
更新日期:2002-08-01 00:00:00
abstract::Despite the growing use of drug-eluting stents, restenosis remains to occur especially in high risk subgroups like patients with diffuse in-stent restenosis. This observation is supporting the search for new and potentially even more effective drug eluting stent systems. Everolimus has been used in conjunction with a ...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1540-8183.2004.04080.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Ideally, percutaneous, mechanical closure of defects of the atrial septum should completely resolve shunt. To achieve this goal, more information is needed about the factors associated with device failure. METHODS:Consecutive patients with cryptogenic neurological events who had severe baseline Valsalva shu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2011.00644.x
更新日期:2011-08-01 00:00:00
abstract:OBJECTIVES:We derived a formula for maximal suggested door-in-door-out time (DIDO) for hospitals that do not perform primary percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI). BACKGROUND:Efforts to minimize DIDO at non-PCI hospitals can improve door-to-balloon time (D2B). Targetin...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12074
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to identify potential predictors, including clinical, procedural, angiographic, and intravascular ultrasound (IVUS) parameters, for recurrent in-stent restenosis (ISR) following beta-radiation 90Strontium/Yttrium (90Sr/Y) in a large multicenter trial. BACKGROUND:Although adjunct...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1540-8183.2006.00188.x
更新日期:2006-10-01 00:00:00
abstract::Results from clinical trials of glycoprotein IIb/IIIa(GPIIb/IIIa) inhibitors during the past decade have established their current role in the treatment of non-ST-segment elevation acute coronary syndrome and in percutaneous coronary interventions. However, there are still unanswered questions on optimal use of GPIIb/...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2006.00182.x
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:Hemostasis following transradial cardiac catheterization is achieved by external pressure application using various devices, TR Band being one. There is no standardized protocol for the application and removal of such devices. OBJECTIVE:To assess the safety and feasibility of a more rapid (1 hour) initiat...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1540-8183.2009.00501.x
更新日期:2009-12-01 00:00:00
abstract:OBJECTIVES:We sought to evaluate the patterns of use and outcomes associated with eptifibatide and abciximab administration among dialysis patients who underwent percutaneous coronary intervention (PCI). BACKGROUND:Contraindicated medications are frequently administered to dialysis patients undergoing PCI often result...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12388
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Prevalence of patent foramen ovale (PFO) with detectable right-to-left shunt is higher in young adults with transient ischemic attack (TIA) and stroke compared to the general population. So far, published series included different occluder systems, various indications and regimens of postprocedural anticoagu...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2010.00593.x
更新日期:2011-02-01 00:00:00
abstract::Achieving controlled flow between the systemic and pulmonary venous circulations is desirable in many complex congenital heart diseases. This includes the Fontan circulation, primary pulmonary hypertension, double inlet ventricles, or hypoplastic left heart with obstruction to the atrioventricular valve. As no specifi...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00155.x
更新日期:2006-08-01 00:00:00
abstract:INTRODUCTION:Sirolimus-eluting stents (SES) have demonstrated low target vessel revascularizations and low incidence of angiographic restenosis in several clinical scenarios. The aim of the present study was to assess the efficacy and safety of SES for the treatment of proximal left anterior descending coronary artery ...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2006.00119.x
更新日期:2006-04-01 00:00:00
abstract:INTRODUCTION:Nonsurgical closure of pathologic vascular communications can be achieved by coil embolization. Different systems used in patients with congenital heart disease (e.g., patent ductus arteriosus) allow controlled release of the devices. However, they are too stiff for coil occlusion of small or tortuous vess...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2001.tb00338.x
更新日期:2001-06-01 00:00:00
abstract::The incidence and morbidity associated with stent fracture are unknown. Recommendations and evidence-based treatment are lacking. We report a case of symptomatic fracture of a sirolimus-eluting stent advancing from the left main into the circumflex coronary artery, forming an acute angle with calcifications at the hin...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章,评审
doi:10.1111/j.1540-8183.2009.00484.x
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Intramyocardial injection of bone marrow cells (BMC) in refractory angina patients with chronic myocardial ischemia has shown to be safe and improve clinical status during short-term follow-up. However, scarce data are available on long-term (>12 months) safety and efficacy. Therefore, the occurrence of clin...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/joic.12408
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Drug-eluting stents have been shown to reduce the incidence of restenosis and target vessel revascularization (TVR) compared with bare metal stents (BMSs); however, the long-term efficacy of sirolimus-eluting stent (SES) implantation in patients with acute coronary syndrome (ACS) has not been w...
journal_title:Journal of interventional cardiology
pub_type: 杂志文章
doi:10.1111/j.1540-8183.2009.00446.x
更新日期:2009-06-01 00:00:00
abstract:PURPOSE:In patients on oral anticoagulation (OAC) undergoing coronary stenting (PCI-S), procedural management and in-hospital outcome have never been specifically and prospectively investigated. Also, the contribution of early bleeding to the relevant hemorrhagic rate reported at follow-up with triple therapy of OAC, a...
journal_title:Journal of interventional cardiology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1540-8183.2009.00468.x
更新日期:2009-08-01 00:00:00