Abstract：
:The purpose of this study was to evaluate morphologically the tongue of individuals with chronic Chagas disease (CD) in comparison to the non-chagasic ones. Twenty-four protocol cases of autopsies were selected. They were subdivided into CD patients (10 cases) and non-chagasic ones (14 cases). The morphometric analysis was accomplished for the tongue muscle and salivary glands duct lumen area. In three CD patients, perineuritis was found, and two of them showed megaesophagus and megacolon. The intensity of the inflammation in the von Ebner's glands, the tongue muscles, and the salivary glands duct lumen area was significantly higher in the CD patients. We concluded that the CD patients show salivary glands duct dilatation, which probably would have a relation with alterations in the autonomic nervous system. The inflammation found in CD patients is in accordance with that described in comparative studies on the digestive tract and heart. These morphological findings suggest that the histopathological analysis of the tongue associated with other organs, or even in an isolated manner, can add in the diagnosis and pathogenesis of the CD chronic phase.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
de Lima Pereira SA,Rodrigues DB,da Fonseca Ferraz ML,da Cunha Castro EC,dos Reis MA,de Paula Antunes Teixeira Vdoi
10.1007/s00436-005-0023-9subject
Has Abstractpub_date
2006-01-01 00:00:00pages
153-6issue
2eissn
0932-0113issn
1432-1955journal_volume
98pub_type
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